Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Romain Vuillefroy de Silly"'
Autor:
Elisabetta Cribioli, Greta Maria Paola Giordano Attianese, Pierpaolo Ginefra, Amandine Signorino-Gelo, Romain Vuillefroy de Silly, Nicola Vannini, Christoph Hess, Melita Irving, George Coukos
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Despite the tremendous success of adoptive T-cell therapies (ACT) in fighting certain hematologic malignancies, not all patients respond, a proportion experience relapse, and effective ACT of most solid tumors remains elusive. In order to improve res
Externí odkaz:
https://doaj.org/article/4281944bf7cc4a21b14d4315acba88d6
Autor:
Gaël Boivin, Pierre-Benoit Ancey, Romain Vuillefroy de Silly, Pradeep Kalambaden, Caroline Contat, Benoit Petit, Jonathan Ollivier, Jean Bourhis, Etienne Meylan, Marie-Catherine Vozenin
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
The anti-Ly6G antibody is used to deplete Ly6Gpos neutrophils and study their role in diverse pathologies. However, depletion is never absolute, as Ly6Glow neutrophils resistant to depletion rapidly emerge. Studying the functionality of these residua
Externí odkaz:
https://doaj.org/article/d859437683ad47369e5adee3a49c5195
Autor:
Cristina Riccadonna, Céline Yacoub Maroun, Romain Vuillefroy de Silly, Margaux Boehler, Marta Calvo Tardón, Simone Jueliger, Pietro Taverna, Leticia Barba, Eliana Marinari, Serena Pellegatta, Esen Yonca Bassoy, Denis Martinvalet, Pierre-Yves Dietrich, Paul R Walker
Publikováno v:
PLoS ONE, Vol 11, Iss 8, p e0162105 (2016)
Malignant gliomas are aggressive brain tumours with very poor prognosis. The majority of glioma cells are differentiated (glioma-differentiated cells: GDCs), whereas the smaller population (glioma-initiating cells, GICs) is undifferentiated and resis
Externí odkaz:
https://doaj.org/article/72e60fa9bc9e436c83a4f1a186e53b28
Autor:
Yaquelin Ortiz-Miranda, Maria Masid, Cristina Jiménez-Luna, Galia Magela Montalvo Bereau, Tania Muller, Nicolas Rayroux, Elisabetta Cribioli, Jesús Corría-Osorio, Helen Carrasco Hope, Romain Vuillefroy de Silly, Bili Seijo, Pierpaolo Ginefra, Kalet León, Nicola Vannini, Ping-Chih Ho, Isaac Crespo, Vassily Hatzimanikatis, Melita Irving, George Coukos
SummaryInterleukin-2 receptor (IL-2R)-mediated intracellular signaling is a key regulator of T-cell fate decisions. While the potent signals generated by IL-2 engagement execute effector differentiation, elevated metabolic activities and rapid cellul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a54cc544864cfa0ccfa381ec77d49301
https://doi.org/10.1101/2023.05.24.541283
https://doi.org/10.1101/2023.05.24.541283
Autor:
Madiha Derouazi, Céline Yacoub Maroun, Laura Ducimetiere, Romain Vuillefroy De Silly, Paul R. Walker, Pierre-Yves Dietrich
Publikováno v:
European Journal of Immunology. 45:2263-2275
CD8(+) T cells controlling pathogens or tumors must function at sites where oxygen tension is frequently low, and never as high as under atmospheric culture conditions. However, T-cell function in vivo is generally analyzed indirectly, or is extrapol
Publikováno v:
Frontiers in Immunology
T-cells play a critical role in tumor immunity. Indeed, the presence of tumor-infiltrating lymphocytes is a predictor of favorable patient prognosis for many indications and is a requirement for responsiveness to immune checkpoint blockade therapy ta
Publikováno v:
Oncoimmunology
T Lymphocytes face pathologically low O2 tensions within the tumor bed at which they will have to function in order to impact on the malignancy. Recent studies highlighting the importance of O2 and hypoxia-inducible factors for CD8+ T-cell function a
Autor:
Esen Yonca Bassoy, Margaux Boehler, Marta Calvo Tardón, Céline Yacoub Maroun, Pietro Taverna, Pierre-Yves Dietrich, Cristina Riccadonna, Romain Vuillefroy De Silly, Simone Jueliger, Denis Martinvalet, Leticia Barba, Paul R. Walker, Serena Pellegatta, Eliana Marinari
Publikováno v:
PLOS ONE, Vol. 11, No 8 (2016) P. e0162105
PLoS ONE, Vol 11, Iss 8, p e0162105 (2016)
PLoS ONE
PLoS ONE, Vol 11, Iss 8, p e0162105 (2016)
PLoS ONE
Malignant gliomas are aggressive brain tumours with very poor prognosis. The majority of glioma cells are differentiated (glioma-differentiated cells: GDCs), whereas the smaller population (glioma-initiating cells, GICs) is undifferentiated and resis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb7c3cdccaf74938b3b574dfc2bbf304
https://archive-ouverte.unige.ch/unige:89480
https://archive-ouverte.unige.ch/unige:89480
BACKGROUND: (blind field) METHODS: We studied a clonal population of gp100 antigen-specific CD8+ T cells from pmel-1 mice and the assays were performed in vitro in a hypoxia work station. 5% O2 corresponds to the expected oxygen fraction in lymph nod
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87491c0f5161462b72435abf7abae9ae
https://europepmc.org/articles/PMC4144613/
https://europepmc.org/articles/PMC4144613/
Autor:
Claire Usal, Anne-Sophie Dugast, Romain Vuillefroy de Silly, Bernard Martinet, Pamela Thebault, Karine Renaudin, Nicolas Poirier, Michèle Heslan, Fabienne Haspot, Flora Coulon, Thomas Haudebourg, Helga Smit, Bernard Vanhove
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(12)
The immune tolerance to rat kidney allografts induced by a perioperative treatment with anti-CD28 Abs is associated with a severe unresponsiveness of peripheral blood cells to donor Ags. In this model, we identified an accumulation in the blood of CD