Zobrazeno 1 - 10
of 33
pro vyhledávání: '"Romain Valabrègue"'
Autor:
Julien Lagarde, Pauline Olivieri, Matteo Tonietto, Camille Noiray, Stéphane Lehericy, Romain Valabrègue, Fabien Caillé, Philippe Gervais, Martin Moussion, Michel Bottlaender, Marie Sarazin
Publikováno v:
Alzheimer’s Research & Therapy, Vol 16, Iss 1, Pp 1-11 (2024)
Abstract Background The locus coeruleus (LC) and the nucleus basalis of Meynert (NBM) are altered in early stages of Alzheimer’s disease (AD). Little is known about LC and NBM alteration in limbic-predominant age-related TDP-43 encephalopathy (LATE
Externí odkaz:
https://doaj.org/article/283489cd1ad14008b765a46806349f86
Autor:
Rahul Gaurav, Romain Valabrègue, Lydia Yahia-Chérif, Graziella Mangone, Sridar Narayanan, Isabelle Arnulf, Marie Vidailhet, Jean-Christophe Corvol, Stéphane Lehéricy
Publikováno v:
NeuroImage: Clinical, Vol 36, Iss , Pp 103250- (2022)
Background: Parkinson’s disease (PD) demonstrates neurodegenerative changes in the substantia nigra pars compacta (SNc) using neuromelanin-sensitive (NM)-MRI. As SNc manual segmentation is prone to substantial inter-individual variability across ra
Externí odkaz:
https://doaj.org/article/8cc340beba6a4e0996942050384bf3f2
Autor:
Pauline Olivieri, Julien Lagarde, Stéphane Lehericy, Romain Valabrègue, Adeline Michel, Pierre Macé, Fabien Caillé, Philippe Gervais, Michel Bottlaender, Marie Sarazin
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 6, Iss 7, Pp 1345-1351 (2019)
Abstract Neuropathological studies showed early locus coeruleus (LC) neuronal loss associated with tauopathy in Alzheimer’s Disease (AD). We used the LC signal intensity (LC‐I) on 3T MRI to assess the LC integrity in AD (n = 37) and controls (n =
Externí odkaz:
https://doaj.org/article/328f34bba83f41298c1e5b801b8158db
Autor:
Valéry Ozenne, Charlotte Constans, Pierre Bour, Mathieu D. Santin, Romain Valabrègue, Harry Ahnine, Pierre Pouget, Stephane Lehéricy, Jean-François Aubry, Bruno Quesson
Publikováno v:
NeuroImage, Vol 204, Iss , Pp 116236- (2020)
Background: Transcranial focus ultrasound applications applied under MRI-guidance benefit from unrivaled monitoring capabilities, allowing the recording of real-time anatomical information and biomarkers like the temperature rise and/or displacement
Externí odkaz:
https://doaj.org/article/ffffc0c5b77944f3b5b0d4dc431bf703
Autor:
Véronique Marchal, Jason Sellers, Mélanie Pélégrini-Issac, Cécile Galléa, Eric Bertasi, Romain Valabrègue, Brian Lau, Pierre Leboucher, Eric Bardinet, Marie-Laure Welter, Carine Karachi
Publikováno v:
PLoS ONE, Vol 14, Iss 10, p e0223494 (2019)
The human gait program involves many brain areas such as motor cortices, cerebellum, basal ganglia, brainstem, and spinal cord. The mesencephalic locomotor region (MLR), which contains the pedunculopontine (PPN) and cuneiform (CN) nuclei, is thought
Externí odkaz:
https://doaj.org/article/133695c93132475c90ba6528610e1f81
Autor:
Vincent Perlbarg, Justine Lambert, Benjamin Butler, Mehdi Felfli, Romain Valabrègue, Anne-Laure Privat, Stéphane Lehéricy, Alexandra Petiet
Publikováno v:
PLoS ONE, Vol 13, Iss 9, p e0202597 (2018)
Parkinson's disease is characterized by neurodegeneration of the dopaminergic neurons in the substantia nigra pars compacta. The 6-hydroxydopamine (6-OHDA) rat model has been used to study neurodegeneration in the nigro-striatal dopaminergic system.
Externí odkaz:
https://doaj.org/article/4cce726a860549d6a48a03490f3dee5f
Autor:
Julien Lagarde, Romain Valabrègue, Jean-Christophe Corvol, Fanny Pineau, Isabelle Le Ber, Marie Vidailhet, Bruno Dubois, Richard Levy
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e80353 (2013)
Progressive supranuclear palsy (PSP) and frontotemporal lobar degeneration (FTD) are two clinicohistological entities that share a severe prefrontal syndrome. To what extent do the cognitive syndrome and the location of the underlying brain atrophy u
Externí odkaz:
https://doaj.org/article/41974ac391f04ff29f5805581911a162
Autor:
Alexis Nobileau, Rahul Gaurav, Lydia Chougar, Alice Faucher, Romain Valabrègue, Graziella Mangone, Smaranda Leu‐Semenescu, François‐Xavier Lejeune, Jean‐Christophe Corvol, Isabelle Arnulf, Marie Vidailhet, David Grabli, Bertrand Degos, Stéphane Lehéricy
Publikováno v:
Movement disorders : official journal of the Movement Disorder SocietyReferences.
The locus coeruleus/subcoeruleus complex (LC/LsC) is a structure comprising melanized noradrenergic neurons.To study the LC/LsC damage across Parkinson's disease (PD) and atypical parkinsonism in a large group of subjects.We studied 98 healthy contro
Autor:
Rahul Gaurav, Nadya Pyatigorskaya, Emma Biondetti, Romain Valabrègue, Lydia Yahia‐Cherif, Graziella Mangone, Smaranda Leu‐Semenescu, Jean‐Christophe Corvol, Marie Vidailhet, Isabelle Arnulf, Stéphane Lehéricy
Publikováno v:
Movement Disorders
Movement Disorders, 2022, ⟨10.1002/mds.28933⟩
Movement Disorders, 2022, ⟨10.1002/mds.28933⟩
Isolated REM sleep behavior disorder (iRBD) is considered a prodromal stage of parkinsonism. Neurodegenerative changes in the substantia nigra pars compacta (SNc) in parkinsonism can be detected using neuromelanin-sensitive MRI.To investigate SNc neu
Autor:
Lydia Chougar, Emina Arsovic, Rahul Gaurav, Emma Biondetti, Alice Faucher, Romain Valabrègue, Nadya Pyatigorskaya, Gwendoline Dupont, François‐Xavier Lejeune, Florence Cormier, Jean‐Christophe Corvol, Marie Vidailhet, Bertrand Degos, David Grabli, Stéphane Lehéricy
Publikováno v:
Movement Disorders
Movement Disorders, In press, ⟨10.1002/mds.28988⟩
Movement Disorders, In press, ⟨10.1002/mds.28988⟩
International audience; Background: Neurodegeneration in the substantia nigra pars compacta (SNc) in parkinsonian syndromes may affect the nigral territories differently.Objective: The objective of this study was to investigate the regional selectivi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05ab7858919eb10bcb780bb93b69f998
https://hal.sorbonne-universite.fr/hal-03644235/document
https://hal.sorbonne-universite.fr/hal-03644235/document