Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Romain Sube"'
Autor:
Romain Sube, Eric A. Ertel
Publikováno v:
Journal of Biomedical Science and Engineering. 10:527-549
Introduction: Cardiomyocytes derived from human induced pluripotent stem cells (hiPSC-CM) form spontaneously beating syncytia in-vitro. We evaluated whether hiPSC-CM are a compelling model of human cardiac pharmacology useful for early drug developme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05b711ee41ca118a9a522c7c3b92361
https://doi.org/10.4236/jbise.2017.1011040
https://doi.org/10.4236/jbise.2017.1011040
Publikováno v:
Journal of Visualized Experiments : JoVE
Spontaneously contracting syncytia of cardiomyocytes derived from human-induced pluripotent stem cells (hiPSC-CM) are a useful model of human cardiac physiology and pharmacology. Various methods have been proposed to record this spontaneous activity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cfbb80eb078d56ef4ce24bf4a2d9473
https://doi.org/10.3791/58290
https://doi.org/10.3791/58290
Publikováno v:
Journal of Bacteriology. 191:2985-2992
The proteinVirB8 plays a critical role in the assembly and function of the Agrobacterium tumefaciens virB type IV secretion system (T4SS). The structure of the periplasmic domain of both A . tumefaciens and Brucella suis VirB8 has been determined, an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d52c7eb48782716e08e45b8292e1cf9
https://doi.org/10.1128/jb.01426-08
https://doi.org/10.1128/jb.01426-08
Autor:
Marina Dos Santos, Daniel Ritz, Verena Kaegi, Azely Mirre, Maria Weiss, Stéphanie Kraemer, Daniel Bur, Michel Enderlin-Paput, Jean-Christophe Gauvin, Hakim Hadana, Georg Rueedi, Thierry Bruyère, Christian Hubschwerlen, Peter Seiler, Mika Gaertner, Jonathan Delers, Christopher Kohl, Wolfgang Keck, Jean-Philippe Surivet, Hans H. Locher, Patrick Hess, Eric A. Ertel, Cornelia Zumbrunn, Romain Sube
Publikováno v:
Journal of medicinal chemistry. 58(2)
Novel antibacterial drugs that are effective against infections caused by multidrug resistant pathogens are urgently needed. In a previous report, we have shown that tetrahydropyran-based inhibitors of bacterial type II topoisomerases (DNA gyrase and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e943cd2f129c2bf098a7a5867bb79e41
https://pubmed.ncbi.nlm.nih.gov/25494934
https://pubmed.ncbi.nlm.nih.gov/25494934
Autor:
Mathias Hafner, Jasmin Giller, Jörg Huwyler, Stephan Krähenbühl, Swen Seeland, Alexander Treiber, Helene Kettiger, Andrea Kiss, Romain Sube, Mark Murphy
Publikováno v:
Pharmacology Research & Perspectives
Under pathological conditions, the purinergic P2X7 receptor is activated by elevated concentrations of extracellular ATP. Thereby, the receptor forms a slowly dilating pore, allowing cations and, upon prolonged stimulation, large molecules to enter t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22fabde18cadbd0c1e679530ad48b7fd
https://doi.org/10.1002/prp2.123
https://doi.org/10.1002/prp2.123