Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Romain Paoli-Lombardo"'
Autor:
Nicolas Primas, Caroline Castera-Ducros, Romain Paoli-Lombardo, Christophe Curti, Fanny Mathias, Pascal Rathelot, Pascal Marchand, Patrice Vanelle
Publikováno v:
Drugs and Drug Candidates, Vol 3, Iss 1, Pp 209-243 (2024)
The Group for the Promotion of Pharmaceutical Chemistry in Academia (GP2A) held its 31st annual conference in August 2023 at the Faculty of Pharmacy of Aix-Marseille University, Marseille, France. There were 8 keynote presentations, 10 early career r
Externí odkaz:
https://doaj.org/article/31102bf7b86c4aaaa5206d2b658c0158
Autor:
Oscar Leonardo Avendaño Leon, Christophe Curti, Fabiana Maia Santos Urbancg Moncorvo, Youssef Kabri, Sébastien Redon, Eduardo Caio Torres-Santos, Romain Paoli-Lombardo, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 4, p M1736 (2023)
As part of our ongoing research into the antileishmanial properties of amidoxime derivatives, we report a preliminary assessment of the antiparasitic properties of a novel compound, diethyl (5-benzyl-2-(4-(N′-hydroxycarbamimidoyl)phenyl)-5-methyl-4
Externí odkaz:
https://doaj.org/article/e55fadfa457e490a80ac0f4274d10c39
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Caroline Castera-Ducros, Inès Jacquet, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1633 (2023)
In continuation of our research program to develop original synthetic methods using TDAE methodology on nitroheterocyclic substrates, we were able to generate for the first time a stable carbanion in position 2 of the 5-nitroimidazole scaffold. Start
Externí odkaz:
https://doaj.org/article/9f9158897187433290e0cbdaba25f26e
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 2, p M1613 (2023)
As part of our ongoing antikinetoplastid structure–activity relationship study focused on positions 2 and 8 of the 3-nitroimidazo[1,2-a]pyridine scaffold, we were able to introduce a phenylthioether moiety at both position 2 and position 8 in one s
Externí odkaz:
https://doaj.org/article/f58d35b14a0c426d88c30e519caa15b5
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sébastien Hutter, Sandra Bourgeade-Delmas, Clotilde Boudot, Caroline Castera-Ducros, Inès Jacquet, Bertrand Courtioux, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Molbank, Vol 2023, Iss 1, p M1573 (2023)
As part of our ongoing scaffold-hopping work on an antikinetoplastid 3-nitroimidazo[1,2-a]pyridine scaffold, we explored 3-nitroimidazo[1,2-b]pyridazine as a potential new antikinetoplastid series. Using conditions previously described by our lab, we
Externí odkaz:
https://doaj.org/article/0c445725dd5148d0b7e1e45358e35a5a
Autor:
Romain Paoli-Lombardo, Nicolas Primas, Sandra Bourgeade-Delmas, Sébastien Hutter, Alix Sournia-Saquet, Clotilde Boudot, Emilie Brenot, Caroline Castera-Ducros, Sophie Corvaisier, Marc Since, Aurélie Malzert-Fréon, Bertrand Courtioux, Alexis Valentin, Pierre Verhaeghe, Nadine Azas, Pascal Rathelot, Patrice Vanelle
Publikováno v:
Pharmaceuticals, Vol 15, Iss 8, p 998 (2022)
An antileishmanial structure–activity relationship (SAR) study focused on positions 2 and 8 of the imidazo[1,2-a]pyridine ring was conducted through the synthesis of 22 new derivatives. After being screened on the promatigote and axenic amastigote
Externí odkaz:
https://doaj.org/article/83013cdfb1b946f190f6b3a926203f86
Autor:
Alexis Valentin, Pierre Verhaeghe, Patrice Vanelle, Sophie Corvaisier, Damián Muruzabal, Caroline Castera-Ducros, Nadine Azas, Sébastien Hutter, Emilie Pinault, Alexandre Destere, Alan H. Fairlamb, Clotilde Boudot, Cyril Fersing, Pascal Rathelot, Susan Wyllie, Sandra Bourgeade-Delmas, Alix Sournia-Saquet, Aurélie Malzert-Fréon, Julien Pedron, Bertrand Courtioux, Amaya Azqueta, Marc Since, Jean Luc Stigliani, Nicolas Primas, Carole Di Giorgio, Youssef Kabri, Romain Paoli-Lombardo
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 206, pp.112668. ⟨10.1016/j.ejmech.2020.112668⟩
International audience; To study the antikinetoplastid 3-nitroimidazo[1,2-a]pyridine pharmacophore, a structure-activity relationship study was conducted through the synthesis of 26 original derivatives and their in vitro evaluation on both Leishmani
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8da65e5f41670c644ea019b322c91450
https://hal.archives-ouvertes.fr/hal-02920293
https://hal.archives-ouvertes.fr/hal-02920293
Autor:
Line Seguy, Cyril Fersing, Sébastien Hutter, Marc Since, Alexandre Destere, Bertrand Courtioux, Julien Pedron, Sophie Corvaisier, Elisa Boutet-Robinet, Pascal Rathelot, Alexis Valentin, Alix Sournia-Saquet, Jean Yves Brossas, Caroline Castera-Ducros, Dominique Mazier, Sandra Bourgeade-Delmas, Aurélie Malzert-Fréon, Susan Wyllie, Romain Paoli-Lombardo, Clotilde Boudot, Patrice Vanelle, Jean Luc Stigliani, Nicolas Primas, Luc Paris, Nadine Azas, Emilie Pinault, Pierre Verhaeghe, Alan H. Fairlamb
Publikováno v:
European Journal of Medicinal Chemistry
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, Elsevier, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
European Journal of Medicinal Chemistry, 2020, 202, pp.112558. ⟨10.1016/j.ejmech.2020.112558⟩
International audience; An antikinetoplastid pharmacomodulation study was done at position 8 of a previously identified pharmacophore in 3-nitroimidazo[1,2-a]pyridine series. Twenty original derivatives bearing an alkynyl moiety were synthesized via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b6cc3d229c60b69b5d7d326afce492d
https://hal.inrae.fr/hal-02899751
https://hal.inrae.fr/hal-02899751