Zirconium-Catalyzed Hydroalumination of C═O Bonds: Site-Selective De-O-acetylation of Peracetylated Compounds and Mechanistic Insights

Autor: Romain M. Q. Renard, Thomas Lecourt, Vincent Gandon, Thibaut Courant, Marine Gavel, Antoine Joosten

Publikováno v: The Journal of Organic Chemistry. 86:9280-9288

An unprecedented hydroalumination of C ═ O bonds catalyzed by zirconocene dichloride is reported herein and applied to the site-selective deprotection of peracetylated functional substrates. A mixed metal hydride, with 1:1 zirconium/aluminum stoich

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ebe8d4b229f8c131490842634c87b76d
https://doi.org/10.1021/acs.joc.1c00060

Regioselective Pd-Catalyzed Carbopalladation/Decarboxylative Allylic Alkynylation of ortho -Iodoallenamides with Alkynyl Carboxylic Acids

Autor: Romain M. Q. Renard, Christophe Hoarau, Jonathan Hédouin, Isabelle Gillaizeau, Cédric Schneider, Vincent Carpentier

Publikováno v: Journal of Organic Chemistry
Journal of Organic Chemistry, American Chemical Society, 2019, 84 (16), pp.10535-10545. ⟨10.1021/acs.joc.9b01408⟩
Journal of Organic Chemistry, 2019, 84 (16), pp.10535-10545. ⟨10.1021/acs.joc.9b01408⟩

International audience; A regioselective Pd-catalyzed domino carbopalladation/decarboxylative allylic alkynylation of ortho-iodoallenamides with alkynyl carboxylic acids was studied. This domino process, based on the consecutive formation of C(sp2)�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::516cb095ee1e1928407e3e57bf9cc978
https://hal-normandie-univ.archives-ouvertes.fr/hal-02282525