Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Romain Guilhaumou"'
Autor:
Romain Guilhaumou, Constance Chevrier, Jean Loup Setti, Elisabeth Jouve, Amélie Marsot, Nathan Julian, Olivier Blin, Pierre Simeone, David Lagier, Djamel Mokart, Nicolas Bruder, Marc Garnier, Lionel Velly
Publikováno v:
Antibiotics, Vol 12, Iss 8, p 1289 (2023)
Background: The aims of this study were to describe pharmacokinetic/pharmacodynamic target attainment in intensive care unit (ICU) patients treated with continuously infused ß-lactam antibiotics, their associated covariates, and the impact of dosage
Externí odkaz:
https://doaj.org/article/1d9e600d3eef492694e7a261a461c810
Autor:
Jenny Becam, Edouard Martin, Gildas Pouradier, Natalia Doudka, Caroline Solas, Romain Guilhaumou, Nicolas Fabresse
Publikováno v:
Toxics, Vol 11, Iss 5, p 464 (2023)
We report a case of accidental nicotine intoxication following transdermal exposure in a 22-year-old man with no medical history, who worked in a company manufacturing e-liquids for electronic cigarettes. He accidentally spilled 300 mL of pure nicoti
Externí odkaz:
https://doaj.org/article/8ddf01db86114fa598f0314b48f3a722
Autor:
Peggy Gandia, Sarah Decheiver, Manon Picard, Romain Guilhaumou, Sarah Baklouti, Didier Concordet
Publikováno v:
Antibiotics, Vol 12, Iss 3, p 515 (2023)
Surprisingly, misinterpretation of the influence of hypoalbuminemia on pharmacokinetics and the clinical effects of drugs seems to be a current problem, even though hypoalbuminemia has no impact on the pharmacologically active exposure. Exceptions to
Externí odkaz:
https://doaj.org/article/2f18c3a0c345439c8e1a4b43d29016a0
Autor:
Clémence Lacroix, Isabelle Alleman-Brimault, Arnaud Zalta, Frank Rouby, Catherine Cassé-Perrot, Elisabeth Jouve, Laurence Attolini, Romain Guilhaumou, Joëlle Micallef, Olivier Blin
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Medical use of cannabis has been receiving growing attention over the last few decades in modern medicine. As we know that the endocannabinoid system is largely involved in neurological disorders, we focused on the scientific rationale of medical can
Externí odkaz:
https://doaj.org/article/96c809222cca4072b1cc51e970df6c3b
Autor:
Romain Guilhaumou, Sihem Benaboud, Youssef Bennis, Claire Dahyot-Fizelier, Eric Dailly, Peggy Gandia, Sylvain Goutelle, Sandrine Lefeuvre, Nicolas Mongardon, Claire Roger, Julien Scala-Bertola, Florian Lemaitre, Marc Garnier
Publikováno v:
Critical Care, Vol 23, Iss 1, Pp 1-20 (2019)
Abstract Background Beta-lactam antibiotics (βLA) are the most commonly used antibiotics in the intensive care unit (ICU). ICU patients present many pathophysiological features that cause pharmacokinetic (PK) and pharmacodynamic (PD) specificities,
Externí odkaz:
https://doaj.org/article/a95e4bbf19074fbd8efce22c8038c53a
Autor:
Camille Riff, Axel Le Caloch, Julien Dupouey, Laurent Allanioux, Marc Leone, Olivier Blin, Aurélie Bourgoin, Romain Guilhaumou
Publikováno v:
Pharmaceutics, Vol 14, Iss 4, p 708 (2022)
Background: Local anesthetic systemic toxicity (LAST) has been reported as a serious complication of local anesthetic (LA) peripheral injection. The signs and symptoms of LAST are highly variable, and the challenge remains to confirm its diagnosis. I
Externí odkaz:
https://doaj.org/article/293d79b4a5204d7aa73bec25d620c81b
Autor:
Clémence Lacroix, Annie-Pierre Bera-Jonville, François Montastruc, Lionel Velly, Joëlle Micallef, Romain Guilhaumou
Publikováno v:
Antibiotics, Vol 10, Iss 5, p 540 (2021)
We described ceftriaxone-induced CNS adverse events through the largest case series of Adverse Drug Reactions (ADRs) reports, from 1995 to 2017, using the French Pharmacovigilance Database. In total, 152 cases of serious CNS ADRs were analyzed; 112 p
Externí odkaz:
https://doaj.org/article/64ef58b9bd244d3a98cd0275badc02d2
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 20 (2017)
Background: Parkinson’s disease is the second most common neurodegenerative disorder after Alzheimer’s disease. Although levodopa remains the single effective agent in the management of Parkinson’s disease, the accurate determination of this op
Externí odkaz:
https://doaj.org/article/27137a12a5664b3295df3fe04395a22f
Akademický článek
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Autor:
Hugo Alarcan, Pauline Cannet, Vincent Camus, Guillaume Fond, Xavier Zendjidjian, Romain Guilhaumou, Sylvie Quaranta
Publikováno v:
British Journal of Clinical Pharmacology. 89:1665-1671
Cytochrome P450 1A2 (CYP1A2) is involved in the metabolism of antipsychotic drugs such as clozapine and olanzapine. Personalization of these treatments requires an accurate estimation of CYP1A2 activity. In this study, we aimed (1) to evaluate the co