Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Romain Guerillot"'
Autor:
Liam K. R. Sharkey, Romain Guerillot, Calum J. Walsh, Adrianna M. Turner, Jean Y. H. Lee, Stephanie L. Neville, Stephan Klatt, Sarah L. Baines, Sacha J. Pidot, Fernando J. Rossello, Torsten Seemann, Hamish E. G. McWilliam, Ellie Cho, Glen P. Carter, Benjamin P. Howden, Christopher A. McDevitt, Abderrahman Hachani, Timothy P. Stinear, Ian R. Monk
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTAmong the 16 two-component systems in the opportunistic human pathogen Staphylococcus aureus, only WalKR is essential. Like the orthologous systems in other Bacillota, S. aureus WalKR controls autolysins involved in peptidoglycan remodeling a
Externí odkaz:
https://doaj.org/article/b925679724c74489887fb31d58cddb66
Autor:
Stefano G. Giulieri, Sarah L. Baines, Romain Guerillot, Torsten Seemann, Anders Gonçalves da Silva, Mark Schultz, Ruth C. Massey, Natasha E. Holmes, Timothy P. Stinear, Benjamin P. Howden
Publikováno v:
Genome Medicine, Vol 10, Iss 1, Pp 1-17 (2018)
Abstract Background Large-scale genomic studies of within-host diversity in Staphylococcus aureus bacteraemia (SAB) are needed to understanding bacterial adaptation underlying persistence and thus refining the role of genomics in management of SAB. H
Externí odkaz:
https://doaj.org/article/4c4c8a7aa28747b592555343cf708772
Autor:
Marion Herisse, Jessica L. Porter, Romain Guerillot, Takehiro Tomita, Anders Goncalves Da Silva, Torsten Seemann, Benjamin P. Howden, Timothy P. Stinear, Sacha J. Pidot
Publikováno v:
PeerJ, Vol 6, p e4784 (2018)
Plasmid vectors based on bacteriophage integrases are important tools in molecular microbiology for the introduction of foreign DNA, especially into bacterial species where other systems for genetic manipulation are limited. Site specific integrases
Externí odkaz:
https://doaj.org/article/9b154ccf7fbb4358ac7ea90e94069f39
Autor:
Abdoulie Bojang, Matthew Chung, Bully Camara, Isatou Jagne, Romain Guérillot, Ebrahim Ndure, Benjamin P Howden, Anna Roca, Elodie Ghedin
Publikováno v:
BMC Infectious Diseases, Vol 24, Iss 1, Pp 1-10 (2024)
Abstract Staphylococcus aureus is a major cause of neonatal infections in various anatomical sites, resulting in high morbidity and mortality in The Gambia. These clinical infections are often preceded by nasal carriage of S. aureus, a known risk fac
Externí odkaz:
https://doaj.org/article/0b50949c957148b8a0b6006b808e3907
Autor:
Sacha J, Pidot, Wei, Gao, Andrew H, Buultjens, Ian R, Monk, Romain, Guerillot, Glen P, Carter, Jean Y H, Lee, Margaret M C, Lam, M Lindsay, Grayson, Susan A, Ballard, Andrew A, Mahony, Elizabeth A, Grabsch, Despina, Kotsanas, Tony M, Korman, Geoffrey W, Coombs, J Owen, Robinson, Anders, Gonçalves da Silva, Torsten, Seemann, Benjamin P, Howden, Paul D R, Johnson, Timothy P, Stinear
Publikováno v:
Science translational medicine. 10(452)
Alcohol-based disinfectants and particularly hand rubs are a key way to control hospital infections worldwide. Such disinfectants restrict transmission of pathogens, such as multidrug-resistant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9b3d34975eeb81fd66962342dd5fcf6
https://pubmed.ncbi.nlm.nih.gov/30273640
https://pubmed.ncbi.nlm.nih.gov/30273640
Autor:
Andre Mu, William P. Klare, Sarah L. Baines, C. N. Ignatius Pang, Romain Guérillot, Nichaela Harbison-Price, Nadia Keller, Jonathan Wilksch, Nguyen Thi Khanh Nhu, Minh-Duy Phan, Bernhard Keller, Brunda Nijagal, Dedreia Tull, Saravanan Dayalan, Hwa Huat Charlie Chua, Dominik Skoneczny, Jason Koval, Abderrahman Hachani, Anup D. Shah, Nitika Neha, Snehal Jadhav, Sally R. Partridge, Amanda J. Cork, Kate Peters, Olivia Bertolla, Stephan Brouwer, Steven J. Hancock, Laura Álvarez-Fraga, David M. P. De Oliveira, Brian Forde, Ashleigh Dale, Warasinee Mujchariyakul, Calum J. Walsh, Ian Monk, Anna Fitzgerald, Mabel Lum, Carolina Correa-Ospina, Piklu Roy Chowdhury, Robert G. Parton, James De Voss, James Beckett, Francois Monty, Jessica McKinnon, Xiaomin Song, John R. Stephen, Marie Everest, Matt I. Bellgard, Matthew Tinning, Michael Leeming, Dianna Hocking, Leila Jebeli, Nancy Wang, Nouri Ben Zakour, Serhat A. Yasar, Stefano Vecchiarelli, Tonia Russell, Thiri Zaw, Tyrone Chen, Don Teng, Zena Kassir, Trevor Lithgow, Adam Jenney, Jason N. Cole, Victor Nizet, Tania C. Sorrell, Anton Y. Peleg, David L. Paterson, Scott A. Beatson, Jemma Wu, Mark P. Molloy, Anna E. Syme, Robert J. A. Goode, Adam A. Hunter, Grahame Bowland, Nicholas P. West, Marc R. Wilkins, Steven P. Djordjevic, Mark R. Davies, Torsten Seemann, Benjamin P. Howden, Dana Pascovici, Sonika Tyagi, Ralf B. Schittenhelm, David P. De Souza, Malcolm J. McConville, Jonathan R. Iredell, Stuart J. Cordwell, Richard A. Strugnell, Timothy P. Stinear, Mark A. Schembri, Mark J. Walker
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-21 (2023)
Severe sepsis has a high mortality rate. Here, the authors provide genomic, transcriptomic, proteomic and metabolomic data across four sepsis-causing pathogens and identify a signature of global increase in fatty acid and lipid biosynthesis as well a
Externí odkaz:
https://doaj.org/article/6d65b18b91de403488fe5eca204df6be
Autor:
Maiken Mellergaard, Sarah Line Skovbakke, Stine Dam Jepsen, Nafsika Panagiotopoulou, Amalie Bøge Rud Hansen, Weihua Tian, Astrid Lund, Rikke Illum Høgh, Sofie Hedlund Møller, Romain Guérillot, Ashleigh S. Hayes, Lise Tornvig Erikstrup, Lars Andresen, Anton Y. Peleg, Anders Rhod Larsen, Timothy P. Stinear, Aase Handberg, Christian Erikstrup, Benjamin P. Howden, Steffen Goletz, Dorte Frees, Søren Skov
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT Staphylococcus aureus (S. aureus) represents a major clinical challenge due to its explicit capacity to select mutations that increase antibiotic resistance and immune evasion. However, the molecular mechanisms are poorly defined, especially
Externí odkaz:
https://doaj.org/article/817c94db797b4d7f9d66769bae0854a0
Autor:
Abderrahman Hachani, Stefano G Giulieri, Romain Guérillot, Calum J Walsh, Marion Herisse, Ye Mon Soe, Sarah L Baines, David R Thomas, Shane Doris Cheung, Ashleigh S Hayes, Ellie Cho, Hayley J Newton, Sacha Pidot, Ruth C Massey, Benjamin P Howden, Timothy P Stinear
Publikováno v:
eLife, Vol 12 (2023)
Staphylococcus aureus infections are associated with high mortality rates. Often considered an extracellular pathogen, S. aureus can persist and replicate within host cells, evading immune responses, and causing host cell death. Classical methods for
Externí odkaz:
https://doaj.org/article/e82ea6004aa84c7a85147fb813e13a3a
Autor:
Stefano G Giulieri, Romain Guérillot, Sebastian Duchene, Abderrahman Hachani, Diane Daniel, Torsten Seemann, Joshua S Davis, Steven YC Tong, Bernadette C Young, Daniel J Wilson, Timothy P Stinear, Benjamin P Howden
Publikováno v:
eLife, Vol 11 (2022)
During severe infections, Staphylococcus aureus moves from its colonising sites to blood and tissues and is exposed to new selective pressures, thus, potentially driving adaptive evolution. Previous studies have shown the key role of the agr locus in
Externí odkaz:
https://doaj.org/article/d46656b345a048bf8feb6be3f7d1c714
Autor:
Stefano G. Giulieri, Romain Guérillot, Jason C. Kwong, Ian R. Monk, Ashleigh S. Hayes, Diane Daniel, Sarah Baines, Norelle L. Sherry, Natasha E. Holmes, Peter Ward, Wei Gao, Torsten Seemann, Timothy P. Stinear, Benjamin P. Howden
Publikováno v:
mBio, Vol 11, Iss 6 (2020)
ABSTRACT Antistaphylococcal penicillins such as oxacillin are the key antibiotics in the treatment of invasive methicillin-susceptible Staphylococcus aureus (MSSA) infections; however, mec gene-independent resistance adaptation can cause treatment fa
Externí odkaz:
https://doaj.org/article/16e4fb535fb74b31acb798bc483a9ccc