Proximity Interactome Analysis of Super Conserved Receptors Expressed in the Brain Identifies EPB41L2, SLC3A2, and LRBA as Main Partners

Autor: Abeer Kaafarani, Romain Darche-Gabinaud, Xavier Bisteau, Virginie Imbault, Valérie Wittamer, Marc Parmentier, Isabelle Pirson

Publikováno v: Cells, Vol 12, Iss 22, p 2625 (2023)

The Super-Conserved Receptors Expressed in the Brain (SREBs) form a subfamily of orphan G protein-coupled receptors, highly conserved in evolution and characterized by a predominant expression in the brain. The signaling pathways activated by these r

Externí odkaz: https://doaj.org/article/75110abea3fc4ec1b16687b41b3633fa

Sulf2a controls Shh-dependent neural fate specification in the developing spinal cord

Autor: Amir Al Oustah, Cathy Danesin, Philippe Cochard, Nathalie Escalas, David Ohayon, Bruno Glise, Cathy Soula, Vanessa Bouguetoch, Romain Darche-Gabinaud

Publikováno v: Scientific Reports
Scientific Reports, Nature Publishing Group, 2021, 11 (1), ⟨10.1038/s41598-020-80455-2⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-17 (2021)

Sulf2a belongs to the Sulf family of extracellular sulfatases which selectively remove 6-O-sulfate groups from heparan sulfates, a critical regulation level for their role in modulating the activity of signalling molecules. Data presented here define

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0d009e97c22451e57fa9340f49bbc35
https://hal.archives-ouvertes.fr/hal-03366122