Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Romain Cayrol"'
Autor:
Jie Pan, Jaume Fores-Martos, Claire Delpirou Nouh, Tanner D. Jensen, Kristen Vallejo, Romain Cayrol, Saman Ahmadian, Euan A. Ashley, Michael D. Greicius, Inma Cobos
Publikováno v:
Acta Neuropathologica Communications, Vol 12, Iss 1, Pp 1-21 (2024)
Abstract CSF1R-related disorder (CSF1R-RD) is a neurodegenerative condition that predominantly affects white matter due to genetic alterations in the CSF1R gene, which is expressed by microglia. We studied an elderly man with a hereditary, progressiv
Externí odkaz:
https://doaj.org/article/274c1c8cf2c746b398593b20211d6b78
Autor:
Jean-Frederic Olivier, David Langlais, Thiviya Jeyakumar, Maria J. Polyak, Luc Galarneau, Romain Cayrol, Hua Jiang, Kelly R. Molloy, Guoyue Xu, Harumi Suzuki, John LaCava, Philippe Gros, Nassima Fodil
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-19 (2024)
Abstract CCDC88B is a risk factor for several chronic inflammatory diseases in humans and its inactivation causes a migratory defect in DCs in mice. CCDC88B belongs to a family of cytoskeleton-associated scaffold proteins that feature protein:protein
Externí odkaz:
https://doaj.org/article/d603e15e96f84a3bbb6cf6e92186e573
Autor:
Quan Zhou, Johana C. M. Vega Leonel, Michelle Rai Santoso, Christy Wilson, Nynke S. van den Berg, Carmel T. Chan, Muna Aryal, Hannes Vogel, Romain Cayrol, Michael J. Mandella, Frank Schonig, Guolan Lu, Sanjiv S. Gambhir, Michael E. Moseley, Eben L. Rosenthal, Gerald A. Grant
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract The prognosis for high-grade glioma (HGG) remains dismal and the extent of resection correlates with overall survival and progression free disease. Epidermal growth factor receptor (EGFR) is a biomarker heterogeneously expressed in HGG. We a
Externí odkaz:
https://doaj.org/article/221b0fd8becb4a9a9cf3556f71c46c2e
Autor:
Typhaine Gris, Patrick Laplante, Paméla Thebault, Romain Cayrol, Ahmed Najjar, Benjamin Joannette-Pilon, Frédéric Brillant-Marquis, Elsa Magro, Shane W. English, Réjean Lapointe, Michel Bojanowski, Charles L. Francoeur, Jean-François Cailhier, on behalf of the Canadian Critical Care Translational Biology Group
Publikováno v:
Journal of Neuroinflammation, Vol 16, Iss 1, Pp 1-16 (2019)
Abstract Background Aneurysmal subarachnoid hemorrhage (SAH) is a catastrophic disease with devastating consequences, including a high mortality rate and severe disabilities among survivors. Inflammation is induced following SAH, but the exact role a
Externí odkaz:
https://doaj.org/article/cf807618ddec4f168a80da39fe6b4434
Publikováno v:
Human Pathology: Case Reports, Vol 20, Iss , Pp 200377- (2020)
Segmental arterial mediolysis (SAM) is a non-inflammatory, non-atherosclerotic arteriopathy of unknown etiology mostly described in adults and involving abdominal arteries. Pathologically a non-inflammatory degeneration of the media of muscular arter
Externí odkaz:
https://doaj.org/article/4114e581899a468bb86b7559b074e4ea
Autor:
Ning Wu, Vitalij Cernysiov, Dominique Davidson, Hua Song, Jianlong Tang, Shanshan Luo, Yan Lu, Jin Qian, Ivayla E. Gyurova, Stephen N. Waggoner, Vincent Quoc-Huy Trinh, Romain Cayrol, Ayumu Sugiura, Heidi M. McBride, Jean-François Daudelin, Nathalie Labrecque, André Veillette
Publikováno v:
Cell Reports, Vol 30, Iss 4, Pp 1129-1140.e5 (2020)
Summary: Plasma membrane damage and cell death during processes such as necroptosis and apoptosis result from cues originating intracellularly. However, death caused by pore-forming agents, like bacterial toxins or complement, is due to direct extern
Externí odkaz:
https://doaj.org/article/b902e275039c4186ad6fa875592cf5d5
Autor:
Nassima Fodil, Neda Moradin, Vicki Leung, Jean-Frederic Olivier, Irena Radovanovic, Thiviya Jeyakumar, Manuel Flores Molina, Ashley McFarquhar, Romain Cayrol, Dominique Bozec, Naglaa H. Shoukry, Michiaki Kubo, Julia Dimitrieva, Edouard Louis, Emilie Theatre, Stephanie Dahan, Yukihide Momozawa, Michel Georges, Garabet Yeretssian, Philippe Gros
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
Hook-related protein family member CCDC88b is encoded by a locus that has been associated with inflammatory bowel disease. Here the authors show that Ccdc88b inactivation in T cells prevents colitis in a transfer model, and detect high colonic levels
Externí odkaz:
https://doaj.org/article/1ef769869ff946e8995e6d2e8381e531
Autor:
Marc Charabati, Stephanie Zandee, Antoine P Fournier, Olivier Tastet, Karine Thai, Roxaneh Zaminpeyma, Marc-André Lécuyer, Lyne Bourbonnière, Sandra Larouche, Wendy Klement, Camille Grasmuck, Fiona Tea, Bettina Zierfuss, Ali Filali-Mouhim, Robert Moumdjian, Alain Bouthillier, Romain Cayrol, Evelyn Peelen, Nathalie Arbour, Catherine Larochelle, Alexandre Prat
Publikováno v:
Brain. 146:1483-1495
The trafficking of autoreactive leucocytes across the blood–brain barrier endothelium is a hallmark of multiple sclerosis pathogenesis. Although the blood–brain barrier endothelium represents one of the main CNS borders to interact with the infil
Autor:
Gabrielle Arbour, Benjamin Ellezam, Alexander G Weil, Romain Cayrol, Magimairajan Issai Vanan, Hallie Coltin, Valérie Larouche, Craig Erker, Nada Jabado, Sébastien Perreault
Publikováno v:
Neuro-oncology advances. 4(1)
Background High-grade gliomas (HGG) with BRAFV600E mutation represent a unique subset of central nervous system tumors. Targeted therapies including BRAF and MEK inhibitors are now being explored as possible new treatment options. Methods We report a
Autor:
Romain Cayrol, Eben L. Rosenthal, Christy Wilson, Gerald A. Grant, Michael E. Moseley, Hannes Vogel, Michael J. Mandella, Muna Aryal, Johana C. M. Vega Leonel, Sanjiv S. Gambhir, Carmel T. Chan, Quan Zhou, Nynke S. van den Berg, Frank Schonig, Michelle R. Santoso, Guolan Lu
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
The prognosis for high-grade glioma (HGG) remains dismal and the extent of resection correlates with overall survival and progression free disease. Epidermal growth factor receptor (EGFR) is a biomarker heterogeneously expressed in HGG. We assessed t