BiœmuS: A new tool for neurological disorders studies through real-time emulation and hybridization using biomimetic Spiking Neural Network

Autor: Romain Beaubois, Jérémy Cheslet, Tomoya Duenki, Giuseppe De Venuto, Marta Carè, Farad Khoyratee, Michela Chiappalone, Pascal Branchereau, Yoshiho Ikeuchi, Timothée Levi

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)

Abstract Characterization and modeling of biological neural networks has emerged as a field driving significant advancements in our understanding of brain function and related pathologies. As of today, pharmacological treatments for neurological diso

Externí odkaz: https://doaj.org/article/8d9e6586800b4af9ae46bbd8e06dcf9a

Complex activity and short-term plasticity of human cerebral organoids reciprocally connected with axons

Autor: Tatsuya Osaki, Tomoya Duenki, Siu Yu A. Chow, Yasuhiro Ikegami, Romain Beaubois, Timothée Levi, Nao Nakagawa-Tamagawa, Yoji Hirano, Yoshiho Ikeuchi

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)

Abstract An inter-regional cortical tract is one of the most fundamental architectural motifs that integrates neural circuits to orchestrate and generate complex functions of the human brain. To understand the mechanistic significance of inter-region

Externí odkaz: https://doaj.org/article/8eab1ffaee0b4b20bfe8d8d28e28b874

From real-time single to multicompartmental Hodgkin-Huxley neurons on FPGA for bio-hybrid systems

Autor: Romain Beaubois, Farad Khoyratee, Pascal Branchereau, Yoshiho Ikeuchi, Timothee Levi

Publikováno v: 2022 44th Annual International Conference of the IEEE Engineering in Medicine & Biology Society (EMBC).

Modeling biological neural networks has been a field opening to major advances in our understanding of the mechanisms governing the functioning of the brain in normal and pathological conditions. The emergence of real-time neuromorphic platforms has

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::49f0ed65fdc4835ccf2985066e6481fc
https://doi.org/10.1109/embc48229.2022.9871176

Low power and massively parallel simulation of oscillatory biochemical networks on FPGA

Autor: Serge Le Thanh, Romain Beaubois, Teruo Fujii, Anthony J. Genot, Nicolas Lobato-Dauzier, Timothée Levi, Farad Khoyratee

Publikováno v: 2019 IEEE Biomedical Circuits and Systems Conference (BioCAS)
2019 IEEE Biomedical Circuits and Systems Conference (BioCAS), Oct 2019, Nara, Japan. pp.1-4, ⟨10.1109/BIOCAS.2019.8919020⟩
BioCAS

International audience; Biological functions emerge from a multitude of chemical species woven into intricate biochemical networks. It is crucial to compute the dynamics of a biochemical network from its kinetics and topology. In order to reverse eng

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf10d1298741c751670b5132a508ca8a
https://hal.archives-ouvertes.fr/hal-02406013