Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Romain, Loyon"'
Autor:
Angélique Vienot, Franck Monnien, Caroline Truntzer, Virginie Mougey, Adeline Bouard, Jean‐René Pallandre, Chloé Molimard, Romain Loyon, Kamal Asgarov, Gerlinde Averous, François Ghiringhelli, Frédéric Bibeau, Paul Peixoto, Christophe Borg
Publikováno v:
Molecular Oncology, Vol 17, Iss 7, Pp 1356-1378 (2023)
Pancreatic ductal adenocarcinoma (PDAC) is marked by molecular heterogeneity and poor prognosis. Among the stemness‐related transcription factors, Spalt‐like Transcription Factor 4 (SALL4) is correlated with unfavorable outcomes; however, its rol
Externí odkaz:
https://doaj.org/article/ea9d65ce32e541b799510c0589dc9be3
Autor:
Laura Mansi, Olivier Adotevi, Marie Kroemer, Laurie Spehner, Adeline Bouard, Marine Jary, Romain Loyon, Christophe Borg, Dewi Vernerey, Syrine Abdeljaoued, Myriam Ben Khelil, Quentin Lepiller, Emeline Orillard, Antoine Falcoz, Hamadi Almotlak, Stefano Kim, Elsa Curtit, Guillaume Meynard, Charlee Nardin, Kamal Asgarov, Ugo Chartral, Virginie Mougey, Morgane Lopez
Publikováno v:
BMJ Oncology, Vol 2, Iss 1 (2023)
Objective Vaccinated patients with cancer in follow-up studies showed a high seropositivity rate but impaired antibody titres and T cell responses following mRNA vaccine against COVID-19. Besides clinical characteristics and the type of anticancer tr
Externí odkaz:
https://doaj.org/article/663b163dc2b0462e8a3aaeff70cda4cf
Autor:
Myriam Ben Khelil, Luc Aeberli, Marie Perchaud, Raphael Genolet, Syrine Abdeljaoued, Christophe Borg, Delphine Binda, Alexandre Harari, Camilla Jandus, Georges Muller, Romain Loyon
Publikováno v:
SLAS Technology, Vol 27, Iss 2, Pp 130-134 (2022)
Reverse immunology has open the door to innovative cancer immunotherapy strategies such as immunogenic antigen-based vaccination and transgenic T cell receptor (TCR)-based adoptive cell transfer. This approach enables the identification of immunogeni
Externí odkaz:
https://doaj.org/article/6792cbf0a52247d1985e803f652cbf23
Autor:
Angélique Vienot, Jean-René Pallandre, Elodie Renaude, Julien Viot, Adeline Bouard, Laurie Spehner, Marie Kroemer, Syrine Abdeljaoued, Bas van der Woning, Hans de Haard, Romain Loyon, Eric Hervouet, Paul Peixoto, Christophe Borg
Publikováno v:
OncoImmunology, Vol 11, Iss 1 (2022)
Combining immunogenic cell death-inducing chemotherapies and PD-1 blockade can generate remarkable tumor responses. It is now well established that TGF-β1 signaling is a major component of treatment resistance and contributes to the cancer-related i
Externí odkaz:
https://doaj.org/article/baa9317abb2648f583e8924e70d7f5b7
Autor:
Giuseppe Ercolano, Alejandra Gomez-Cadena, Nina Dumauthioz, Giulia Vanoni, Mario Kreutzfeldt, Tania Wyss, Liliane Michalik, Romain Loyon, Angela Ianaro, Ping-Chih Ho, Christophe Borg, Manfred Kopf, Doron Merkler, Philippe Krebs, Pedro Romero, Sara Trabanelli, Camilla Jandus
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Group 2 innate lymphoid cells (ILC2s) are a component of type 2 immune response recently described to be involved in the regulation of anti-tumor immune responses. Here, the authors show that the expression of the peroxisome proliferator-activated re
Externí odkaz:
https://doaj.org/article/b884462c3efa444ba2a11976dff87142
Autor:
Marie Kroemer, Bruno Heyd, Romain Loyon, Christophe Borg, Syrine Abdeljaoued, Sara Arfa, Myriam Ben Khelil, Angélique Vienot, Alexandre Doussot
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 4 (2022)
Externí odkaz:
https://doaj.org/article/64bcf2df5a3a43199722e8978ee7209a
Autor:
Elodie Renaude, Marie Kroemer, Christophe Borg, Paul Peixoto, Eric Hervouet, Romain Loyon, Olivier Adotévi
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Evidences highlight the role of various CD4+ helper T cells (CD4+ Th) subpopulations in orchestrating the immune responses against cancers. Epigenetics takes an important part in the regulation of CD4+ Th polarization and plasticity. In this review,
Externí odkaz:
https://doaj.org/article/291928e2de864f3b876293c40387eabb
Autor:
Bérengère Salomé, Alejandra Gomez-Cadena, Romain Loyon, Madeleine Suffiotti, Valentina Salvestrini, Tania Wyss, Giulia Vanoni, Dan Fu Ruan, Marianna Rossi, Alessandra Tozzo, Paolo Tentorio, Elena Bruni, Carsten Riether, Eva-Maria Jacobsen, Peter Jandus, Curdin Conrad, Manfred Hoenig, Ansgar Schulz, Katarzyna Michaud, Matteo Giovanni Della Porta, Silvia Salvatore, Ping-Chih Ho, David Gfeller, Adrian Ochsenbein, Domenico Mavilio, Antonio Curti, Emanuela Marcenaro, Alexander Steinle, Amir Horowitz, Pedro Romero, Sara Trabanelli, Camilla Jandus
Publikováno v:
Blood Advances, Vol 3, Iss 22, Pp 3674-3687 (2019)
Abstract: An understanding of natural killer (NK) cell physiology in acute myeloid leukemia (AML) has led to the use of NK cell transfer in patients, demonstrating promising clinical results. However, AML is still characterized by a high relapse rate
Externí odkaz:
https://doaj.org/article/a58692079466456d94844157879e3e54
Autor:
Julien Viot, Syrine Abdeljaoued, Angélique Vienot, Evan Seffar, Laurie Spehner, Adeline Bouard, Kamal Asgarov, Jean-René Pallandre, Elodie Renaude, Elodie Klajer, Chloé Molimard, Franck Monnien, Frederic Bibeau, Celia Turco, Bruno Heyd, Paul Peixoto, Eric Hervouet, Romain Loyon, Alexandre Doussot, Christophe Borg, Marie Kroemer
Publikováno v:
Cellular & Molecular Immunology. 20:365-378
CD226 has been reported to participate in the rescue of CD8+ T cell dysfunction. In this study, we aimed to assess the prognostic value of CD226 in tumor-infiltrating lymphocytes (TILs) derived from colorectal cancer (CRC) liver metastases treated wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43e5acb702eee444ab0df17345a1ff36
https://doi.org/10.1038/s41423-023-00978-2
https://doi.org/10.1038/s41423-023-00978-2
Autor:
Olivier Adotevi, Marie Kroemer, Celia Turco, Laurie Spehner, Julien Viot, Idir Idirène, Adeline Bouard, Elodie Renaude, Marina Deschamps, Yann Godet, Samuel Limat, Bruno Heyd, Marine Jary, Romain Loyon, Christophe Borg
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 8, Iss 2 (2020)
Background The positive role of CD8+ tumor-infiltrating lymphocytes (TIL) in patients with colorectal cancer (CRC) has been well described but the prognostic value of CD4 T cell subsets remained to be investigated. In this study, we expanded TIL from
Externí odkaz:
https://doaj.org/article/7bebc9c3f3704540a3a717f1f980b649