Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Romain, Gioia"'
Autor:
Rachid Abaji, Vincent Roux, Ismahène Reguieg Yssaad, Paloma Kalegari, Vincent Gagné, Romain Gioia, Gerardo Ferbeyre, Christian Beauséjour, Maja Krajinovic
Publikováno v:
Pharmacogenomics. 23:415-430
Aims: To investigate the role of MYBBP1A gene and rs3809849 in pancreatic cancer (PANC1) and lymphoblastic leukemia (NALM6) cell lines and their response to asparaginase treatment. Materials & methods: The authors applied CRISPR-Cas9 to produce MYBBP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5e1b1abcb177afcce1e14e70f3517c58
https://doi.org/10.2217/pgs-2022-0010
https://doi.org/10.2217/pgs-2022-0010
Autor:
Mathieu Lajoie, Simon Drouin, Maxime Caron, Pascal St-Onge, Manon Ouimet, Romain Gioia, Marie-Hélène Lafond, Ramon Vidal, Chantal Richer, Karim Oualkacha, Arnaud Droit, Daniel Sinnett
Publikováno v:
PLoS ONE, Vol 12, Iss 3, p e0174124 (2017)
Pre-B cell childhood acute lymphoblastic leukemia (pre-B cALL) is a heterogeneous disease involving many subtypes typically stratified using a combination of cytogenetic and molecular-based assays. These methods, although widely used, rely on the pre
Externí odkaz:
https://doaj.org/article/2690801a4bc448c4b2f7b9b7b846221b
Autor:
Simon Drouin, Manon Ouimet, Pascal St-Onge, Chantal Richer, Romain Gioia, Maxime Caron, Daniel Sinnett
Publikováno v:
Oncotarget
// Romain Gioia 1 , Simon Drouin 1 , Manon Ouimet 1 , Maxime Caron 1 , Pascal St-Onge 1 , Chantal Richer 1 and Daniel Sinnett 1, 2 1 Division of Hematology-Oncology, Research Center, Sainte-Justine University Health Center, Montreal, QC, Canada 2 Dep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fc39be5eecaf200751841967436fa171
https://pubmed.ncbi.nlm.nih.gov/29113332
https://pubmed.ncbi.nlm.nih.gov/29113332
Autor:
Bruno Robert, Isabelle Vigon, Pierre-Yves Dumas, Vanessa Desplat, Serge Roche, Francois-Xavier Mahon, Valérie Prouzet-Mauléon, Wilhem Leconet, Romain Gioia, Claire Trégoat, Jean-Max Pasquet, Audrey Sirvent, Vincent Praloran, Arnaud Villacreces, Valérie Lagarde, Eric Lippert
Publikováno v:
Journal of Pathology
Journal of Pathology, Wiley, 2015, 237 (1), pp.14--24. ⟨10.1002/path.4561⟩
Journal of Pathology, Wiley, 2015, 237 (1), pp.14--24. ⟨10.1002/path.4561⟩
A tyrosine kinase network composed of the TAM receptor AXL and the cytoplasmic kinases LYN and SYK is involved in nilotinib-resistance of chronic myeloid leukaemia (CML) cells. Here, we show that the E3-ubiquitin ligase CBL down-regulation occurring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d7911566a574940ec8d36d1c06e4d511
https://doi.org/10.1002/path.4561
https://doi.org/10.1002/path.4561
Autor:
Manon Ouimet, Chantal Richer, Daniel Sinnett, Maxime Caron, Simon Drouin, Mathieu Lajoie, Pascal St-Onge, Romain Gioia
Publikováno v:
Oncotarget
// Manon Ouimet 1 , Simon Drouin 1 , Mathieu Lajoie 1 , Maxime Caron 1 , Pascal St-Onge 1 , Romain Gioia 1 , Chantal Richer 1 and Daniel Sinnett 1,2 1 Division of Hematology-Oncology, Research Center, Sainte-Justine University Health Center, Montreal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99e46e758ce809394a67e12558646420
https://pubmed.ncbi.nlm.nih.gov/27980230
https://pubmed.ncbi.nlm.nih.gov/27980230
Autor:
Bruno Cardinaud, Patrick Legembre, Valérie Lagarde, Muriel Priault, Claire Drullion, Eric Lippert, Francois-Xavier Mahon, Romain Gioia, Jean-Max Pasquet
Publikováno v:
Leukemia Research and Treatment
Leukemia Research and Treatment, 2012, 2012, pp.861301. ⟨10.1155/2012/861301⟩
Leukemia Research and Treatment, 2012, 2012, pp.861301. ⟨10.1155/2012/861301⟩
We used K562 cells sensitive or generated resistant to imatinib or nilotinib to investigate their response to mycophenolic acid (MPA). MPA induced DNA damage leading to cell death with a minor contribution of apoptosis, as revealed by annexin V label
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c96a1847f3363664977be262b09737f
https://doi.org/10.1155/2012/861301
https://doi.org/10.1155/2012/861301
Autor:
Jean-Stéphane Gatot, Jacques Piette, Rudi Beyaert, Jean-Paul Chapelle, Alain Chariot, Romain Gioia, Felicia Alina Patrascu, Luke A. J. O'Neill, Tieu-Lan Chau, Isabelle Carpentier
Publikováno v:
Trends in Biochemical Sciences. 33:171-180
The IkappaB kinases (IKKs) IKK-alpha and IKK-beta, and the IKK-related kinases TBK1 and IKK-epsilon, have essential roles in innate immunity through signal-induced activation of NF-kappaB, IRF3 and IRF7, respectively. Although the signaling events wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6644a85658e3d258bee13f932efcdf8
https://doi.org/10.1016/j.tibs.2008.01.002
https://doi.org/10.1016/j.tibs.2008.01.002
Autor:
Eric Muraille, Pierre Close, Jean-Paul Chapelle, Alain Chariot, Jacques Piette, Keith Brown, Emmanuel Dejardin, Felicia Alina Patrascu, Tieu-Lan Chau, Romain Gioia, Jean-Stéphane Gatot, Michael Warnier, Ulrich Siebenlist
Publikováno v:
Journal of Biological Chemistry. 282:31131-31146
Type I interferon gene induction relies on IKK-related kinase TBK1 and IKKepsilon-mediated phosphorylations of IRF3/7 through the Toll-like receptor-dependent signaling pathways. The scaffold proteins that assemble these kinase complexes are poorly c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4919bdd23db6028103385f9e9e3bb08
https://doi.org/10.1074/jbc.m701690200
https://doi.org/10.1074/jbc.m701690200
Autor:
Simon Drouin, Arnaud Droit, Maxime Caron, Karim Oualkacha, Pascal St-Onge, Manon Ouimet, Chantal Richer, Marie-Hélène Lafond, Romain Gioia, Daniel Sinnett, Ramon O. Vidal, Mathieu Lajoie
Publikováno v:
PLoS ONE
PLoS ONE, Vol 12, Iss 3, p e0174124 (2017)
PLoS ONE, Vol 12, Iss 3, p e0174124 (2017)
Pre-B cell childhood acute lymphoblastic leukemia (pre-B cALL) is a heterogeneous disease involving many subtypes typically stratified using a combination of cytogenetic and molecular-based assays. These methods, although widely used, rely on the pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fdd7a329d9c611677cb8d7485f9180c
https://doi.org/10.1371/journal.pone.0174124
https://doi.org/10.1371/journal.pone.0174124
Autor:
Romain, Gioia, Claire, Trégoat, Pierre-Yves, Dumas, Valérie, Lagarde, Valérie, Prouzet-Mauléon, Vanessa, Desplat, Audrey, Sirvent, Vincent, Praloran, Eric, Lippert, Arnaud, Villacreces, Wilhem, Leconet, Bruno, Robert, Isabelle, Vigon, Serge, Roche, François-Xavier, Mahon, Jean-Max, Pasquet
Publikováno v:
The Journal of pathology. 237(1)
A tyrosine kinase network composed of the TAM receptor AXL and the cytoplasmic kinases LYN and SYK is involved in nilotinib-resistance of chronic myeloid leukaemia (CML) cells. Here, we show that the E3-ubiquitin ligase CBL down-regulation occurring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1ff004dcbaeca53a7dd32fe5305b3712
https://pubmed.ncbi.nlm.nih.gov/25965880
https://pubmed.ncbi.nlm.nih.gov/25965880