Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Romain, Cohen"'
Autor:
Vincent Jonchère, Hugo Montémont, Enora Le Scanf, Aurélie Siret, Quentin Letourneur, Emmanuel Tubacher, Christophe Battail, Assane Fall, Karim Labreche, Victor Renault, Toky Ratovomanana, Olivier Buhard, Ariane Jolly, Philippe Le Rouzic, Cody Feys, Emmanuelle Despras, Habib Zouali, Rémy Nicolle, Pascale Cervera, Magali Svrcek, Pierre Bourgoin, Hélène Blanché, Anne Boland, Jérémie Lefèvre, Yann Parc, Mehdi Touat, Franck Bielle, Danielle Arzur, Gwennina Cueff, Catherine Le Jossic-Corcos, Gaël Quéré, Gwendal Dujardin, Marc Blondel, Cédric Le Maréchal, Romain Cohen, Thierry André, Florence Coulet, Pierre de la Grange, Aurélien de Reyniès, Jean-François Fléjou, Florence Renaud, Agusti Alentorn, Laurent Corcos, Jean-François Deleuze, Ada Collura, Alex Duval
Publikováno v:
Genome Biology, Vol 25, Iss 1, Pp 1-26 (2024)
Abstract Background Microsatellite instability (MSI) due to mismatch repair deficiency (dMMR) is common in colorectal cancer (CRC). These cancers are associated with somatic coding events, but the noncoding pathophysiological impact of this genomic i
Externí odkaz:
https://doaj.org/article/87efc7be65b6480c8bf4509103a6aab4
Autor:
Koen Zwart, Frederieke H. van derBaan, Romain Cohen, Thomas Aparicio, Christelle de laFouchardiére, Thierry Lecomte, Cornelis J. A. Punt, David Sefrioui, Rik J. Verheijden, Geraldine R. Vink, G. Emerens Wensink, Aziz Zaanan, Miriam Koopman, David Tougeron, Jeanine M. L. Roodhart
Publikováno v:
Cancer Medicine, Vol 12, Iss 15, Pp 15841-15853 (2023)
Abstract Background Current knowledge on prognostic biomarkers (especially BRAFV600E/RAS mutations) in metastatic colorectal cancer (mCRC) is mainly based on mCRC patients with proficient mismatch repair (pMMR) tumors. It is uncertain whether these b
Externí odkaz:
https://doaj.org/article/78172ed8afd94d10ab4cb901ea49fe41
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 16 (2024)
The microsatellite instability (MSI) phenotype is related to a deficiency of the DNA mismatch repair (dMMR) system and is observed in 5% of metastatic colorectal cancers (mCRCs). MSI/dMMR phenotype testing should be routine for all CRCs regardless of
Externí odkaz:
https://doaj.org/article/0d92af267dc34047ae21eb865d70f084
Autor:
Akihito Kawazoe, Kohei Shitara, Sara Lonardi, Filippo Pietrantonio, Samuel J Klempner, Thierry André, Massimiliano Salati, Margherita Ambrosini, Giovanni Randon, Romain Cohen, Paolo Manca, Vincenzo Nasca, Joseph Chao, Leonardo Provenzano, Yu Aoki, Steven B Maron, Riccardo Cerantola, Lorenzo Fornaro, Walter Ferrari Bravo, Filippo Ghelardi, Valerie Zhu, Darren Cowzer, Virginia Genovesi
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 6 (2023)
Background Subgroup analyses of randomized trials suggest the superiority of immune checkpoint inhibitor-based therapy over chemotherapy in patients with mismatch-repair deficient (dMMR) and/or microsatellite instability-high (MSI-high) advanced gast
Externí odkaz:
https://doaj.org/article/f743b9a859bf4ca78c1d5072f84a6e85
Autor:
Marine Jary, Wen‐Wei Liu, Dongyao Yan, Isaac Bai, Andrea Muranyi, Elise Colle, Isabelle Brocheriou, Anthony Turpin, Nina Radosevic‐Robin, Pierre Bourgoin, Frédérique Penault‐Llorca, Romain Cohen, Dewi Vernerey, Thierry André, Christophe Borg, Kandavel Shanmugam, Magali Svrcek
Publikováno v:
Molecular Oncology, Vol 16, Iss 11, Pp 2260-2273 (2022)
In the era of immune checkpoint inhibitors, understanding the metastatic microenvironment of proficient mismatch repair/microsatellite stable (pMMR/MSS) colorectal cancer (CRC) is of paramount importance to both prognostication and the development of
Externí odkaz:
https://doaj.org/article/528753a036b940b0a01d68a276c317a4
Autor:
Sahir Javed, Stéphane Benoist, Patrick Devos, Stéphanie Truant, Rosine Guimbaud, Astrid Lièvre, David Sefrioui, Romain Cohen, Pascal Artru, Aurélien Dupré, Jean-Baptiste Bachet, Christelle de la Fouchardière, Anne Ploquin, Anthony Turpin
Publikováno v:
World Journal of Surgical Oncology, Vol 20, Iss 1, Pp 1-10 (2022)
Abstract Background BRAF V600E-mutant colorectal cancers (CRCs) are associated with shorter survival than BRAF wild-type tumors. Therapeutic decision-making for colorectal liver metastases (CRLM) harboring this mutation remains difficult due to the s
Externí odkaz:
https://doaj.org/article/396f97762c6d4546b3a537ee0d4435cb
Autor:
Akihito Kawazoe, Kohei Shitara, Chiara Cremolini, Giovanni Fucà, Sara Lonardi, Filippo Pietrantonio, Francesca Corti, Samuel J Klempner, Magali Svrcek, Thierry André, Giuseppe Curigliano, Michael Overman, Francesca Bergamo, Elisabetta Fenocchio, Massimiliano Salati, Margherita Ambrosini, Giovanni Randon, Lisa Salvatore, Romain Cohen, Raphael Colle, Maria Elena Elez, Marwan Fakih, Aakash Tushar Shah, Joseph Chao, Matthew Emmett, Marc Díez García, Giacomo Mazzoli, Leonardo Provenzano, Keigo Chida, Veronica Conca
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 10, Iss 2 (2022)
Background Despite unprecedented benefit from immune checkpoint inhibitors (ICIs) in patients with mismatch repair deficient (dMMR)/microsatellite instability high (MSI-H) advanced gastrointestinal cancers, a relevant proportion of patients shows pri
Externí odkaz:
https://doaj.org/article/0a3c47b59e654946a72b34ac617e8c57
Autor:
Olivier Lucidarme, Mathilde Wagner, Paul Gillard, Stefano Kim, Jean-Baptiste Bachet, Benoit Rousseau, Thibault Mazard, Christophe Louvet, Benoist Chibaudel, Romain Cohen, Marie-Line Garcia-Larnicol, Aurelien Gobert, Julie Henriques, Thierry André
Publikováno v:
Cancer Imaging, Vol 19, Iss 1, Pp 1-8 (2019)
Abstract Background To evaluate the objective response rate (ORR) at 2 months of treatment with regorafenib according to RECIST 1.1, Choi, and modified Choi (mChoi) criteria in patients with metastatic colorectal cancer (mCRC). Methods Baseline and 2
Externí odkaz:
https://doaj.org/article/973c8ae8421d499f81e57995cfc895d0
Autor:
Jun Yin, Shaheenah Dawood, Romain Cohen, Jeff Meyers, John Zalcberg, Takayuki Yoshino, Matthew Seymour, Tim Maughan, Leonard Saltz, Eric Van Cutsem, Alan Venook, Hans-Joachim Schmoll, Richard Goldberg, Paulo Hoff, J. Randolph Hecht, Herbert Hurwitz, Cornelis Punt, Eduard Diaz Rubio, Miriam Koopman, Chiara Cremolini, Volker Heinemann, Christophe Tournigard, Carsten Bokemeyer, Charles Fuchs, Niall Tebbutt, John Souglakos, Jean-Yves Doulliard, Fairooz Kabbinavar, Benoist Chibaudel, Aimery de Gramont, Qian Shi, Axel Grothey, Richard Adams
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 13 (2021)
Background: Benchmarking international cancer survival differences is necessary to evaluate and improve healthcare systems. Our aim was to assess the potential regional differences in outcomes among patients with metastatic colorectal cancer (mCRC) p
Externí odkaz:
https://doaj.org/article/bf4aa20a3f6a47ca83257f0396cc016f
Autor:
Emilie Charton, Jean‐Baptiste Bachet, Pascal Hammel, Jérôme Desramé, Benoist Chibaudel, Romain Cohen, Philippe Debourdeau, Jérome Dauba, Thierry Lecomte, Jean‐François Seitz, Christophe Tournigand, Thomas Aparicio, Véronique Guerin‐Meyer, Julien Taieb, Julien Volet, Christophe Louvet, Amélie Anota, Franck Bonnetain
Publikováno v:
Cancer Medicine, Vol 8, Iss 11, Pp 5079-5088 (2019)
Abstract Background The phase II AFUGEM GERCOR trial aimed to assess the efficacy of a first‐line therapy combining nab‐paclitaxel plus either gemcitabine (gemcitabine group) or simplified leucovorin and fluorouracil (sLV5FU2 group) in patients w
Externí odkaz:
https://doaj.org/article/ea9e9d8aac3c4e91a964a297380cb6f7