Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Roma A. Armstrong"'
Autor:
Roma A. Armstrong
Publikováno v:
International Immunopharmacology. 1:1501-1512
There is contention over whether human neutrophils produce physiologically significant levels of nitric oxide (NO) during inflammatory reactions. Nevertheless, regardless of its cell source, NO does exert regulatory effects on neutrophil function. De
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fcb67aac6331db19749025656421e9df
https://doi.org/10.1016/s1567-5769(01)00094-7
https://doi.org/10.1016/s1567-5769(01)00094-7
Autor:
Jean Louis Sébédio, Bernard Beaufrère, Robert A. Elton, Jean Michel Chardigny, Susan H.F Vermunt, Lionel Bretillon, Rudolph A. Riemersma, Ronald P. Mensink, Roma A. Armstrong, Alison Macvean
Publikováno v:
Thrombosis Research. 100:133-141
The aim of this study was to investigate the effect of trans α-linolenic acid on platelet aggregation and blood haemostasis. A randomized, double blind dietary intervention trial was carried out with healthy male volunteers (n=88) in three European
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e24d45a8d2879f6d457abef03205f449
https://doi.org/10.1016/s0049-3848(00)00309-1
https://doi.org/10.1016/s0049-3848(00)00309-1
Autor:
Roma A. Armstrong
Publikováno v:
Pharmacology & Therapeutics. 72:171-191
Prostaglandins (PGs) and thromboxanes are important modulators of platelet activation, and there is strong evidence to support the existence of distinct thromboxane, prostacyclin, PGD 2 and PGE 2 receptors on the platelet plasma membrane. In this rev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b586b0922d50d20d679a3ce3876ef10d
https://doi.org/10.1016/s0163-7258(96)00103-9
https://doi.org/10.1016/s0163-7258(96)00103-9
Autor:
Roma A. Armstrong
Publikováno v:
British Journal of Pharmacology. 116:2903-2908
1. The aims of this study were to investigate the inhibitory effects of prostaglandin E2 (PGE2) on chemotaxis of N-formyl-methionyl-leucine-phenylalanine (FMLP)-stimulated human neutrophils, and to test the hypothesis that cyclic AMP is the second me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e0d8cac84d6248ba456ba8319370f0e6
https://doi.org/10.1111/j.1476-5381.1995.tb15943.x
https://doi.org/10.1111/j.1476-5381.1995.tb15943.x
Autor:
Roma A. Armstrong, N. H. Wilson
Publikováno v:
General Pharmacology: The Vascular System. 26:463-472
1. The aim of this review is to establish what is known about the thromboxane (TP) receptor, and to identify where future research is headed. In addition, the impact of the recent advances at the molecular level on resolving pharmacological controver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8225fe33db70989ebc2e9f3f9fc106f
https://doi.org/10.1016/0306-3623(94)00183-n
https://doi.org/10.1016/0306-3623(94)00183-n
Publikováno v:
Prostaglandins. 49:225-237
A fourth PGE receptor subtype, the EP4 receptor, has recently been described in the pig saphenous vein (PSV). Similar to the EP2 receptor, it mediates relaxation and is linked to stimulation of adenylate cyclase. The aim of this study was to determin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73868da743c899a1299ac34f695b625f
https://doi.org/10.1016/0090-6980(95)00018-6
https://doi.org/10.1016/0090-6980(95)00018-6
Publikováno v:
Prostaglandins. 49:205-224
The interactions of bradykinin (BK) and FMLP (a leukocyte-dependent mediator of inflammation) with thirteen prostaglandin E analogs have been investigated in a rabbit skin model of inflammation. The PGE analogs were chosen with a view to defining the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dfcd3f86148e2860370d62696eb027e
https://doi.org/10.1016/0090-6980(95)00015-3
https://doi.org/10.1016/0090-6980(95)00015-3
Publikováno v:
British Journal of Pharmacology. 114:1459-1465
1. The aims of this study were to characterize the EP receptor subtype mediating the inhibition of superoxide anion generation by formyl methionyl leucine phenylalanine (FMLP)-stimulated human neutrophils, and to test the hypothesis that adenosine 3'
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44eb1cb3364f457c9262365f4c07e10b
https://doi.org/10.1111/j.1476-5381.1995.tb13370.x
https://doi.org/10.1111/j.1476-5381.1995.tb13370.x
Publikováno v:
British Journal of Pharmacology. 110:539-547
1 The interaction of the specific thromboxane (TP-) receptor blocking drug, [3H]-GR32191 with human intact platelets and platelet membranes has been investigated in vitro. 2 On intact platelets, association of specific [3H]-GR32191 binding at 37°C w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7824369be81769a1e40d6c57ba3575ab
https://doi.org/10.1111/j.1476-5381.1993.tb13844.x
https://doi.org/10.1111/j.1476-5381.1993.tb13844.x
Publikováno v:
British Journal of Pharmacology. 110:548-552
1. Exposure of human resuspended platelets in vitro for 30 min to the potent thromboxane A2 (TP)-receptor blocking drug GR32191, followed by its removal by dilution-dissociation, reduced the degree of subsequent binding to 2 nM [3H]-GR32191 by almost
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214fad1d7fcc695316a374d432ccb72e
https://doi.org/10.1111/j.1476-5381.1993.tb13845.x
https://doi.org/10.1111/j.1476-5381.1993.tb13845.x