Zobrazeno 1 - 10
of 44
pro vyhledávání: '"Rom Langerak"'
Autor:
Sakshi Khurana, Stefano Schivo, Jacqueline R. M. Plass, Nikolas Mersinis, Jetse Scholma, Johan Kerkhofs, Leilei Zhong, Jaco van de Pol, Rom Langerak, Liesbet Geris, Marcel Karperien, Janine N. Post
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 9 (2021)
A fundamental question in cartilage biology is: what determines the switch between permanent cartilage found in the articular joints and transient hypertrophic cartilage that functions as a template for bone? This switch is observed both in a subset
Externí odkaz:
https://doaj.org/article/7987b8cda5b64370984e24d6236274bd
Autor:
Stefano Schivo, Jetse Scholma, Marcel Karperien, Janine N. Post, Jaco van de Pol, Rom Langerak
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 145, Iss Proc. SynCoP 2014, Pp 35-47 (2014)
ANIMO (Analysis of Networks with Interactive MOdeling) is a software for modeling biological networks, such as e.g. signaling, metabolic or gene networks. An ANIMO model is essentially the sum of a network topology and a number of interaction paramet
Externí odkaz:
https://doaj.org/article/da95cd0e91104b5d887cbfbee9a024ba
Publikováno v:
Electronic Proceedings in Theoretical Computer Science, Vol 20, Iss Proc. FMA 2009, Pp 49-62 (2010)
The timed automata formalism is an important model for specifying and analysing real-time systems. Robustness is the correctness of the model in the presence of small drifts on clocks or imprecision in testing guards. A symbolic algorithm for the ana
Externí odkaz:
https://doaj.org/article/8eb4ae1b4be8408e8b996477696b6bb9
Autor:
Jetse Scholma, Liesbet Geris, Janine N. Post, Jaco van de Pol, Sakshi Khurana, Rom Langerak, Stefano Schivo, Kannan Govindaraj, Johan Kerkhofs, Marcel Karperien, Xiaobin Huang, Andre J. van Wijnen, Leilei Zhong
Publikováno v:
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, van de Pol, J, Langerak, R, van Wijnen, A J, Geris, L, Karperien, M & Post, J N 2020, ' ECHO, the executable CHOndrocyte : A computational model to study articular chondrocytes in health and disease ', Cellular Signalling, vol. 68, 109471 . https://doi.org/10.1016/j.cellsig.2019.109471
Cellular Signalling, 68:109471. Elsevier Inc.
Cellular Signalling, 68:109471. Elsevier
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, Pol, J V D, Langerak, R, Wijnen, A J V, Geris, L, Karperien, M & Post, J N 2019, ' ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in healthy and disease ', Cellular Signalling . https://doi.org/10.1016/j.cellsig.2019.109471
Cellular Signalling, 68:109471. Elsevier Inc.
Cellular Signalling, 68:109471. Elsevier
Schivo, S, Khurana, S, Govindaraj, K, Scholma, J, Kerkhofs, J, Zhong, L, Huang, X, Pol, J V D, Langerak, R, Wijnen, A J V, Geris, L, Karperien, M & Post, J N 2019, ' ECHO, the executable CHOndrocyte: A computational model to study articular chondrocytes in healthy and disease ', Cellular Signalling . https://doi.org/10.1016/j.cellsig.2019.109471
Computational modeling can be used to investigate complex signaling networks in biology. However, most modeling tools are not suitable for molecular cell biologists with little background in mathematics. We have built a visual-based modeling tool for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18dd3e18d306a6fd950ea89a5e3420b0
https://hdl.handle.net/1820/c8afbf16-bbcd-4716-a850-c0f96f5f0326
https://hdl.handle.net/1820/c8afbf16-bbcd-4716-a850-c0f96f5f0326
Autor:
Frank Lobbezoo, Umarah Choudry, Peter Wetselaar, Pepijn de Jong, Rom Langerak, Jasper van Rooijen
Publikováno v:
Wetselaar, P, Lobbezoo, F, de Jong, P, Choudry, U, van Rooijen, J & Langerak, R 2020, ' A methodology for evaluating tooth wear monitoring using timed automata modelling ', Journal of Oral Rehabilitation, vol. 47, no. 3, pp. 353-360 . https://doi.org/10.1111/joor.12908
Journal of Oral Rehabilitation
Journal of Oral Rehabilitation, 47(3), 353-360. Wiley-Blackwell
Journal of Oral Rehabilitation
Journal of Oral Rehabilitation, 47(3), 353-360. Wiley-Blackwell
Objectives: Tooth wear is a multifactorial condition leading to the loss of dental hard tissues. A counselling/monitoring protocol is of importance in order to keep that loss as limited as possible. Since many factors are involved and a time span of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d027c024d513ffedbeca7d117f8289f9
https://hdl.handle.net/1871.1/4e493456-8ca5-4ac2-9912-73ec055578d4
https://hdl.handle.net/1871.1/4e493456-8ca5-4ac2-9912-73ec055578d4
This Festschrift volume has been published in honor of Ed Brinksma, on the occasion of his 60th birthday.The contributions in this Festschrift are written by a number of Ed's former Ph.D. students and collaborators. The papers are a reflection on his
Autor:
Schivo, Stefano, Scholma, Jetse, Vet, Paul Van Der, Karperien, Marcel, Post, Janine, Pol, Jaco Van De, Rom Langerak
Additional material on ANIMO and Timed Automata, Notes on the models presented in the Results section, Naming conventions used in the paper, Supplementary figures. (PDF 7270 kb)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5509ea4b937f3fe769c7db8b19e857f7
Autor:
Rom Langerak, Jan Willem Polderman
Publikováno v:
Systems and control letters, 61(9), 904-910. Elsevier
This paper presents a decision algorithm for the analysis of the stability of a class of planar switched linear systems, modeled by hybrid automata. The dynamics in each location of the hybrid automaton is assumed to be linear and asymptotically stab
Autor:
Jaco van de Pol, Stefano Schivo, Marcel Karperien, Paul van der Vet, Jetse Scholma, Janine N. Post, Rom Langerak
Publikováno v:
BMC Systems Biology
BMC systems biology, 10. BioMed Central
BMC systems biology, 10. BioMed Central
Background Computational support is essential in order to reason on the dynamics of biological systems. We have developed the software tool ANIMO (Analysis of Networks with Interactive MOdeling) to provide such computational support and allow insight
Autor:
Paul van der Vet, Marcel Karperien, Stefano Schivo, Brend Wanders, Jetse Scholma, Ricardo A. Urquidi Camacho, Jaco van de Pol, Rom Langerak, Janine N. Post
Publikováno v:
IEEE journal of biomedical and health informatics, 18(3), 832-839. IEEE
Living cells are constantly subjected to a plethora of environmental stimuli that require integration into an appropriate cellular response. This integration takes place through signal transduction events that form tightly interconnected networks. Th