The Effects of pH and PEG 400–Water Cosolvents on Oxytetracycline–Magnesium Complex Formation and Stability

Autor: Rolland I. Poust, Douglas R. Flanagan, Alan M. Goldberg, Sauwaluxana Tongaree

Publikováno v: Pharmaceutical Development and Technology. 5:189-199

The effects of pH and PEG 400 on the stoichiometry, conformation, and stability of the magnesium-oxytetracycline (Mg+2-OTC) complex were evaluated. Circular dichroism (CD) and HPLC were used to investigate Mg+2-OTC complex formation and determine the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67f404e34caa9ba8ca3359001bd81010
https://doi.org/10.1081/pdt-100100534

Recruitment of Participants in the Childhood Asthma Management Program (CAMP). I. Description of Methods

Autor: Suzanne S. Hurd, Harold S. Nelson, Clarence E. Davis, Babi Hammond, Brian Lopez, Diane Becker, Renee Sananes, C. Warren Bierman, Virginia S. Taggart, Betsy Leritz, Bruce G. Bender, Brian Watson, Diana S. Richardson, Colleen Lum Lung, Jennifer Chay, Gail G. Shapiro, Reuben M. Cherniack, N. Franklin Adkinson, Margaret Higham, Ann Whitman, Melody Miki, Yola Benedet, Curtis L. Meinert, Henry Levison, Carolyn Wells, Rosetta Jackson, Sai R. Nimmagadda, Michael P. White, Kenneth Gore, Noah J. Friedman, Bennie McWilliams, Grace Strodtbeck, Selda Bereket, Catherine A. Nelle, Leonard C. Altman, Stephen J. Gaioni, Robert Rice, Stephanie Philips, Mary Caesar, Claire Lawhon, June Traylor, Dirk K. Greineder, Ellen Albers, F. Estelle R. Simons, Frank S. Virant, Marian Sharpe, Jessica Sheridan, Howard Eigen, Elaine M. Jenson, Sydney R. Parker, Cathy Herman, Michael S. Kennedy, Cathleen Ewing, Mary Grace, Jean McAuliffe, James G. Easton, Anne Walker, Ellen Hanson, Jeffrey Jacobs, W. Patrick Buchanan, Paola Pacella, Robert A. Wise, Marcia Hefner, Heather Eliassen, Jeryl Feeley, David Herold, Peter Barrant, Denise Rodgers, Shannon C. Bush, Rhonda Emerick, Walter Torda, Leona Cuttler, Jack Wisenauer, Martha Tata, Janice Ware, Michael W. Smith, Carl Turner, Alan J. Lincoln, Clifton T. Furukawa, Dennis Elbert, Ian MacLusky, Chris Reagan, Mildred Pessaro, Joseph Hassell, Jody Ciacco, Barbara Ortega, Margaret Moreshead, R. Menendez, Dawn Dawson, Anita Hall, Robert G. Hamilton, Kay Seligsohn, John E. Connett, Ann Mullen, Melanie Gleason, Susan Kelleher, Eva Rodriquez, Emily Glynn, Cynthia S. Rand, Mary Spicher, Nancy Boilers, Linda L. Galbreath, Robert Huffman, Michele Donithan, H. William Kelly, Karen Huss, Tina Oliver-Welker, Edwin B. Fisher, Eric Willcutt, Paul S. Albert, Alice L. Sternberg, Michael Flynn, James P. Kiley, Judith Harle, James Tonascia, Cindi Culkin, Barbara Wheeler, Jill Meinert, Dan Crawford, Avraham Moscona, David Evans, Nancy Madden, Jonathan W. Becker, Jessyca Bridges, Tom Lynch, Cynthia Moseid, Sarah Oliver, David Hunt, Gordon R. Bloomberg, Sanford Leikin, Sarma Vadlamani, Arlin Lehman, Gregg Belle, Marisa Dolinsky, Leslie P. Plotnick, Michael Schatz, Marisa Braun, Stephanie Haynes, Nevin W. Wilson, Thomas F. Smith, Michelle Collinson, Senia Pizzo, Pat Belt, D.A. Sundstrom, Christopher Dawson, Joe Reisman, Melissa Van Horn, Trella Washington, Anthony A. Horner, Margaret Wu, Sharon Sagel, Timothy G. Wighton, Carol Schatz, Agnes Martinez, Tamara Chinn, Robert S. Zeiger, Caroline Hendrickson, Paula Parks, Karen Sandoval, A.H. Liu, Margaret B. Pulsifer, Joseph D. Spahn, Ronald J. Harbeck, Meyer Kattan, Michael Mellon, Robert D. Annett, Debra Amend-Libercci, Jane Finlayson-Kulchin, Bernadette D. Heckman, Peyton A. Eggleston, James M. Corry, Vera Edmonds, Pamela Randall, Paul V. Wil-Hams, Kimberly Hyatt, Deborah Nowakowski, Michael Eltz, Daniel Hettleman, Anthony De Filippo, Betty Collison, Kristin Brelsford, John Dodge, Thomas R. DuHamel, Kung Yee Liang, Stanley J. Szefler, Bob Hughes, Kathleen Mostafa, Karen Collins, Rolland I. Poust, Elizabeth P. Ryan, Kendra Sandoval, Dominick A. Minotti, Debra Kemp, Michaela Magiari, Deborah K. White, Anne Plunkett, Dana Mandel, Al Jalowayski, Leonard B. Bacharier, Robert C. Strunk, Mark L. Van Natta, Susan C. Sylvia, Jay Koslof, Charles G. Irvin, Scott T. Weiss, Tara Junk, Kathleen Harden, Alan K. Kamada, Shirley King, Michelle M. Cloutier, Michael H. Clayton

Publikováno v: Scopus-Elsevier

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39eb9fe06f4893890fae2c0b9cec0bd5
https://doi.org/10.3109/02770909909075406

OK-432 Therapy for Lymphangiomas

Autor: Ken Kimura, Richard J.H. Smith, Yutaka Sato, Diane K. Burke, Rolland I. Poust, Nancy M. Bauman

Publikováno v: Archives of Otolaryngology - Head and Neck Surgery. 122:1195-1199

Objective: To assess the efficacy of OK-432 sclerotherapy in the treatment of lymphangiomas. Design: Nonrandomized trial; follow-up, 4 to 29 months. Setting: Academic tertiary referral medical center. Patients: Six children with presumed lymphangioma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df356166ba197966bfa5989039fd8d2a
https://doi.org/10.1001/archotol.1996.01890230041009

Chemical Kinetics and Drug Stability

Autor: J. Keith Guillory, Rolland I. Poust

Publikováno v: Modern Pharmaceutics Volume 1 ISBN: 9780429148286

In the rational design and evaluation of dosage forms for drugs, the stability of the activecomponents must be a major criterion in determining their suitability. Several forms ofinstability can lead to the rejection of a drug product. First, there m

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4a282ac1a6e049a355f44b8c973a9897
https://doi.org/10.3109/9781420065657-10

Influence of Repetitive Dosing and Altered Urinary pH on Doxycycline Excretion in Humans

Autor: Stephen L. Feld, Rolland I. Poust, John L. Colaizzi, James M. Jaffe

Publikováno v: Journal of Pharmaceutical Sciences. 63:1256-1260

The effect of altered urinary pH on the renal excretion of doxycycline, with both single- and multiple-dose regimens, was studied in humans. Alkalinization of the urine resulted in higher cumulative amounts of doxycycline excreted during both single

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99b59565cf7b630a5c219b631d77cff3
https://doi.org/10.1002/jps.2600630819