Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Rolf-Peter Scholz"'
Autor:
Boris Macek, Katharina Schulenburg, Armelle Natsuo Takeda, Attila Reményi, Tripat Kaur Oberoi-Khanuja, Krishnaraj Rajalingam, Alejandro Carpy, Gábor Glatz, Rolf Peter Scholz
Publikováno v:
The EMBO Journal. 33:1784-1801
Mitogen-activated protein kinases (MAPKs) are highly conserved protein kinase modules, and they control fundamental cellular processes. While the activation of MAPKs has been well studied, little is known on the mechanisms driving their inactivation.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::26fa17105ec9acd0f57b276b5ff3d09b
https://doi.org/10.15252/embj.201487808
https://doi.org/10.15252/embj.201487808
Autor:
Carrie L Anderson, Tripat Kaur Oberoi, Kazuhiko Namikawa, Dagmar Meyer zu Heringdorf, Jennifer C. Hocking, Rolf-Peter Scholz, Boris Macek, Gregory S. Harms, Reinhard W. Köster, Alejandro Carpy, Gudula Schmidt, Juliane Mooz, Mika O. Ruonala, Taner Dogan, Christiaan Karreman, Krishnaraj Rajalingam
Publikováno v:
The EMBO Journal. 31:14-28
Inhibitors of apoptosis proteins (IAPs) are a highly conserved class of multifunctional proteins. Rac1 is a well-studied Rho GTPase that controls numerous basic cellular processes. While the regulation of nucleotide binding to Rac1 is well understood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d7fcf104f031b24fdbd22cef044a344a
https://doi.org/10.1038/emboj.2011.423
https://doi.org/10.1038/emboj.2011.423
Autor:
Susanne Ziegler, Rolf-Peter Scholz, Angelika Hausser, Tim Eiseler, Gisela Link, Alexander Beck
Publikováno v:
Molecular Biology of the Cell
RIN1 is a regulator of epithelial cell migration. We identify serine 292 as a novel phosphorylation site for PKD in RIN1. Phosphorylation at this site controls RIN1-mediated inhibition of cell migration by modulating the direct activation of Abl kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ff9710e9a1bb01ee1ed81892468982
https://doi.org/10.1091/mbc.e10-05-0427
https://doi.org/10.1091/mbc.e10-05-0427
DLC1 interacts with 14-3-3 proteins to inhibit RhoGAP activity and block nucleocytoplasmic shuttling
Autor:
Angelika Hausser, Patrik Erlmann, Gerlinde Holeiter, Simone Schmid, Anke Theil, Rolf-Peter Scholz, Monilola A. Olayioye, Jennifer Regner, Ruth Jähne
Publikováno v:
Journal of Cell Science. 122:92-102
Deleted in liver cancer 1 (DLC1) is a Rho-GTPase-activating protein (GAP) that is downregulated in various tumor types. In vitro, DLC1 specifically inactivates the small GTPases RhoA, RhoB and RhoC through its GAP domain and this appears to contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98d559593de766c3091cb10a75c76b48
https://doi.org/10.1242/jcs.036251
https://doi.org/10.1242/jcs.036251
Autor:
Stephan A. Eisler, Monilola A. Olayioye, Simone Schmid, Patrik Erlmann, Mamta Jaiswal, Angelika Hausser, Peter Hoffmann, Rolf-Peter Scholz, Mohammed Reza Ahmadian, Johan O. R. Gustafsson
Deleted in liver cancer 1 (DLC1) is a tumor suppressor protein that is frequently down regulated in various tumor types. DLC1 contains a Rho GTPase activating protein (GAP) domain that appears tobe required for its tumor suppressive functions. Little
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44bba0d7598f9df555844eab3d1f17eb
https://hdl.handle.net/1959.8/162865
https://hdl.handle.net/1959.8/162865
Publikováno v:
Molecular and cellular biology. 25(17)
Dbf4/Cdc7 is required for DNA replication in Saccharomyces cerevisiae and appears to be a target in the S-phase checkpoint. Previously, a 186-amino-acid Dbf4 region that mediates interactions with both the origin recognition complex and Rad53 was ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c12b4df4169c36ee958531b65723fda
https://pubmed.ncbi.nlm.nih.gov/16107698
https://pubmed.ncbi.nlm.nih.gov/16107698
Autor:
Frederic J. de Sauvage, Steffen Durinck, Mark X. Sliwkowski, Kyle A. Edgar, Howard M. Stern, Chaitali Parikh, Zhengyan Kan, Krista K. Bowman, Rolf-Peter Scholz, Somasekar Seshagiri, Jeremy Stinson, Wenlin Yuan, Vasantharajan Janakiraman, Maria N. Lorenzo, Subhra Chaudhuri, Ron Firestein, Jiansheng Wu, Michelle Mak, Emily Chan, Mark Merchant, Charles Eigenbrot, Bijay S. Jaiswal, Zora Modrusan, Joseph Guillory, Brock A. Peters, Kanan Pujara, Eric Stawiski, Hong Li, Gabriele Schaefer, Krishnaraj Rajalingam, Noelyn M. Kljavin
Publikováno v:
Cancer Cell. (4):543-544
SummaryThe human epidermal growth factor receptor (HER) family of tyrosine kinases is deregulated in multiple cancers either through amplification, overexpression, or mutation. ERBB3/HER3, the only member with an impaired kinase domain, although ampl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5201da8376aa97bd311be6169033087