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Autor:
Hiskias G. Keizer, Chris G. Kruse, and Arnoud H. J. Herremans, Janpeter de Moes, Herman H. van Stuivenberg, Hein K. A. C. Coolen, Arnold P. den Hartog, Martin Tulp, Rolf van Hes, Leonarda C. Niemann, Andrew C. McCreary, Rob H. Plekkenpol, Mayke B. Hesselink, Cees N. J. Stroomer, Bob Stork, Pieter Smid
Publikováno v:
Journal of medicinal chemistry. 48(22)
A series of novel bicyclic 1-heteroaryl-4-[omega-(1H-indol-3-yl)alkyl]piperazines was synthesized and evaluated on binding to dopamine D(2) receptors and serotonin reuptake sites. This class of compounds proved to be potent in vitro dopamine D(2) rec