Zobrazeno 1 - 10
of 619
pro vyhledávání: '"Rolf W, Hartmann"'
Autor:
Jelena Konstantinović, Andreas M. Kany, Alaa Alhayek, Ahmed S. Abdelsamie, Asfandyar Sikandar, Katrin Voos, Yiwen Yao, Anastasia Andreas, Roya Shafiei, Brigitta Loretz, Esther Schönauer, Robert Bals, Hans Brandstetter, Rolf W. Hartmann, Christian Ducho, Claus-Michael Lehr, Christoph Beisswenger, Rolf Müller, Katharina Rox, Jörg Haupenthal, Anna K.H. Hirsch
Publikováno v:
ACS Central Science, Vol 9, Iss 12, Pp 2205-2215 (2023)
Externí odkaz:
https://doaj.org/article/ea30f522c5d744fdb5b1cfb4ff499d72
Autor:
Robert Richter, Mohamed.A.M. Kamal, Mariel A. García-Rivera, Jerome Kaspar, Maximilian Junk, Walid A.M. Elgaher, Sanjay Kumar Srikakulam, Alexander Gress, Anja Beckmann, Alexander Grißmer, Carola Meier, Michael Vielhaber, Olga Kalinina, Anna K.H. Hirsch, Rolf W. Hartmann, Mark Brönstrup, Nicole Schneider-Daum, Claus-Michael Lehr
Publikováno v:
Materials Today Bio, Vol 8, Iss , Pp 100084- (2020)
The pipeline of antibiotics has been for decades on an alarmingly low level. Considering the steadily emerging antibiotic resistance, novel tools are needed for early and easy identification of effective anti-infective compounds. In Gram-negative bac
Externí odkaz:
https://doaj.org/article/abcd928f0e8c4f0e83637af5a24dae36
Autor:
Cansu Kaya, Isabell Walter, Alaa Alhayek, Roya Shafiei, Gwenaëlle Jézéquel, Anastasia Andreas, Jelena Konstantinović, Esther Schönauer, Asfandyar Sikandar, Jörg Haupenthal, Rolf Müller, Hans Brandstetter, Rolf W. Hartmann, Anna K.H. Hirsch
Publikováno v:
ACS Infectious Diseases. 8:1010-1021
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e0cc9f4ee20ede994b9052aeda07de0
https://doi.org/10.1021/acsinfecdis.1c00628
https://doi.org/10.1021/acsinfecdis.1c00628
Autor:
Cansu Kaya, Jelena Konstantinović, Andreas M. Kany, Anastasia Andreas, Jan S. Kramer, Steffen Brunst, Lilia Weizel, Marco J. Rotter, Denia Frank, Samir Yahiaoui, Rolf Müller, Rolf W. Hartmann, Jörg Haupenthal, Ewgenij Proschak, Thomas A. Wichelhaus, Anna K. H. Hirsch
Publikováno v:
Journal of Medicinal Chemistry. 65:3913-3922
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ba2b5b359b69016b19595f2e0d6c1f7
https://doi.org/10.1021/acs.jmedchem.1c01755
https://doi.org/10.1021/acs.jmedchem.1c01755
Autor:
Giuseppe Allegretta, Christine K. Maurer, Jens Eberhard, Damien Maura, Rolf W. Hartmann, Laurence Rahme, Martin Empting
Publikováno v:
Frontiers in Microbiology, Vol 8 (2017)
Pseudomonas aeruginosa is a Gram-negative bacterium, which causes opportunistic infections in immuno-compromised individuals. Due to its multiple resistances toward antibiotics, the development of new drugs is required. Interfering with Quorum Sensin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::889c055998baaafeddfda59200ee919a
Autor:
Anne Imberty, Katharina Rox, Thomas Brunner, Stefanie Wagner, Janine Schreiber, Rolf W. Hartmann, Alexander Titz, Annabelle Varrot, Mark Brönstrup, Dirk Hauck, Thomas Ryckmans, Eike-Christian Wamhoff, Roman Sommer, Christoph Rademacher
Publikováno v:
Journal of the American Chemical Society
Journal of the American Chemical Society, American Chemical Society, 2018, 140 (7), pp.2537-2545. ⟨10.1021/jacs.7b11133⟩
'Journal of the American Chemical Society ', vol: 140, pages: 2537-2545 (2018)
Journal of the American Chemical Society, American Chemical Society, 2018, 140 (7), pp.2537-2545. ⟨10.1021/jacs.7b11133⟩
'Journal of the American Chemical Society ', vol: 140, pages: 2537-2545 (2018)
International audience; The opportunistic Gram-negative bacterium Pseudomonas aeruginosa is a leading pathogen for infections of immuno-compromised patients and those suffering from cystic fibrosis. Its ability to switch from planktonic life to aggre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::943a314ab2eb4ed671d42eb281329c9b
Autor:
Katrin Georgi, Rolf W. Hartmann, Anupam Khutia, Lara Rosenberger, Carolina von Essen, Lassina Badolo, Anna K. H. Hirsch, Clemens Kühn
Structural elucidation of small molecules only available in low quantity (nanogram) is one of the big advantages of the crystalline sponge method. The optimization of various soaking parameters is crucial for effective analyte absorption and repetiti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0811d46c86ea01c3d4738290f46dc084
Autor:
Marc Stadler, Fabienne Hennessen, Rolf W. Hartmann, Mark Brönstrup, Samir Yahiaoui, Anna K. H. Hirsch, Rolf Müller, Jennifer Herrmann, Charlotte Grandclaudon, Ravindra P. Jumde, Walid A. M. Elgaher, Stephan Hüttel, N.V. Suryanarayana Birudukota, Marcus Miethke, Nanaji Arisetti
Publikováno v:
European journal of medicinal chemistry
To address the global challenge of emerging antimicrobial resistance, the hitherto most successful strategy to new antibiotics has been the optimization of validated natural products; most of these efforts rely on semisynthesis. Herein, we report the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ec1c596f7ce687e7ef4e22222da110a
Autor:
Nicolas Lebouvier, Fabrice Pagniez, Young Min Na, Da Shi, Patricia Pinson, Mathieu Marchivie, Jean Guillon, Tarek Hakki, Rita Bernhardt, Sook Wah Yee, Claire Simons, Marie-Pierre Lézé, Rolf W. Hartmann, Angélique Mularoni, Guillaume Le Baut, Isabelle Krimm, Ruben Abagyan, Patrice Le Pape, Marc Le Borgne
Publikováno v:
Pharmaceuticals, Vol 13, Iss 8, p 186 (2020)
A series of 2-aryl-3-azolyl-1-indolyl-propan-2-ols was designed as new analogs of fluconazole (FLC) by replacing one of its two triazole moieties by an indole scaffold. Two different chemical approaches were then developed. The first one, in seven st
Externí odkaz:
https://doaj.org/article/63c78164cef14a8ebc00f90e1b524bc6
Autor:
Carla F. Sousa, Mohamed A.M. Kamal, Robert Richter, Kalanika Elamaldeniya, Rolf W. Hartmann, Martin Empting, Claus-Michael Lehr, Olga V. Kalinina
Publikováno v:
Journal of chemical information and modeling. 62(20)
Passive diffusion across biomembranes is an important mechanism of permeation for multiple drugs, including antibiotics. However, this process is frequently neglected while studying drug uptake and, in our view, warrants further investigation. Here,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d6d3d6869117b96ca92190c0b39ed5e
https://pubmed.ncbi.nlm.nih.gov/36214845
https://pubmed.ncbi.nlm.nih.gov/36214845