Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Rolf Vajna"'
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 446:633-640
The HCN4 gene encodes a hyperpolarization-activated cation current contributing to the slow components of the pacemaking currents I(f) in the sinoatrial node and I(h) or I(q) in the thalamus. Heterologous expression studies of individual HCN channels
Autor:
Jürgen Hescheler, Toni Schneider, Udo Klöckner, Alexey Pereverzev, Gabriele Pfitzer, Rolf Vajna
Publikováno v:
European Journal of Endocrinology. :881-889
OBJECTIVE: Multiple types of voltage-activated Ca(2+) channels (T, L, N, P, Q and R type) coordinate a variety of Ca(2+)-dependent processes in neurons and neuroendocrine cells. In insulinoma cell lines as well as in endocrine tissues, the non-L-type
Autor:
Rolf Vajna, Cornelia Gissel, Neil Smyth, Jürgen Hescheler, Margit Henry, Toni Schneider, Marina Mikhna, Marco Weiergräber, Alexey Pereverzev
Publikováno v:
Molecular Endocrinology. 16:884-895
Multiple types of voltage-activated Ca(2+) channels (T, L, N, P, Q, R type) coordinate Ca(2+)-dependent processes in neurons and neuroendocrine cells. Expressional and functional data have suggested a role for Ca(v)2.3 Ca(2+) channels in endocrine pr
Autor:
Xiao-hua Chen, Rolf Vajna, Toni Schneider, Marco Weiergräber, Norbert Klugbauer, Udo Klöckner, George Miljanich, Edward Perez-Reyes, Alexey Pereverzev, Jürgen Hescheler
Publikováno v:
European Journal of Biochemistry. 268:1066-1075
Among voltage-gated Ca2+ channels the non-dihydropyridine-sensitive alpha1E subunit is functionally less well characterized than the structurally related alpha1A (omega-agatoxin-IVA sensitive, P- /Q-type) and alpha1B (omega-conotoxin-GVIA sensitive,
Autor:
Rolf Vajna, Margit Henry, Toni Schneider, Wolfgang Nastainczyk, Marco Weiergräber, Martin Schramm, Alexey Pereverzev, Heike Grabsch
Publikováno v:
Journal of Histochemistry & Cytochemistry. 48:807-819
The calcium channel α1E subunit was originally cloned from mammalian brain. A new splice variant was recently identified in rat islets of Langerhans and in human kidney by the polymerase chain reaction. The same isoform of α1E was detected in rat a
Autor:
Alexey Pereverzev, Daniela Pietrobon, Toni Schneider, Udo Klöckner, Juergen Hescheler, A. Tottene, Rolf Vajna, Martin Schramm
Publikováno v:
Neuroscience. 92:565-575
In primary cultures of rat cerebellar granule cells, transcripts of voltage-gated Ca 2+ channels have been amplified by reverse transcription–polymerase chain reaction and identified by sequencing of subcloned polymerase chain reaction products. In
Autor:
Udo Klöckner, Edward Perez-Reyes, Stefan Arnhold, Toni Schneider, Heike Grabsch, Jürgen Hescheler, Rolf Vajna, Martin Schramm, Alexei Pereverzev
Publikováno v:
European Journal of Biochemistry. 257:274-285
The expression of Ca2+ channel alpha1E isoforms has been analyzed in different cell lines, embryoid bodies and tissues. The comparison of the different cloned alpha1E cDNA sequences led to the prediction of alpha1E splice variants. Transcripts of two
Autor:
S. Olyschläger, Toni Schneider, Heike Grabsch, Rolf Vajna, Juergen Hescheler, Alexey Pereverzev, S. Viatchenko‐Karpinski, R. Schröder, M. Henry, Udo Klöckner
Publikováno v:
European Journal of Neuroscience. 10:916-925
Voltage-operated Ca2+ channels are heteromultimeric proteins. Their structural diversity is caused by several genes encoding homologous subunits and by alternative splicing of single transcripts. Isoforms of alpha1 subunits, which contain the ion con
Autor:
Jürgen Hescheler, Claire O. Malécot, Udo Klöckner, Andreas Krieger, Gabriele Pfitzer, Jérôme Leroy, Alexey Pereverzev, Rolf Vajna, Toni Schneider
Publikováno v:
The European journal of neuroscience. 19(10)
There is growing evidence that E-type voltage dependent Ca 2 + channels (Ca v 2.3) are involved in triggering and controlling pivotal cellular processes like neurosecretion and long-term potentiation. The mechanism underlying a novel Ca 2 + dependent
Autor:
Udo Klöckner, Jérôme Leroy, Toni Schneider, Ning Qin, Alexey Pereverzev, Claire O. Malécot, Jürgen Hescheler, Gabriele Pfitzer, Rolf Vajna
Publikováno v:
The European journal of neuroscience. 18(4)
Ca2+-dependent regulation of L-type and P/Q-type Ca2+ channel activity is an important mechanism to control Ca2+ entry into excitable cells. Here we addressed the question whether the activity of E-type Ca2+ channels can also be controlled by Ca2+. S