Výsledky vyhledávání - "Rolf U, Halden"

Akademický článek

Seasonality of respiratory, enteric, and urinary viruses revealed by wastewater genomic surveillance

Autor: Matthew F. Smith, Rabia Maqsood, Regan A. Sullins, Erin M. Driver, Rolf U. Halden, Efrem S. Lim

Publikováno v: mSphere, Vol 9, Iss 5 (2024)

ABSTRACT Wastewater surveillance can reveal population-level infectious disease burden and emergent public health threats can be reliably assessed through wastewater surveillance. While molecular methods for wastewater monitoring of microorganisms ha

Externí odkaz: https://doaj.org/article/e4a88469d48b4ebc80235f034d04ef65

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Akademický článek

Exploring Canine Picornavirus Diversity in the USA Using Wastewater Surveillance: From High-Throughput Genomic Sequencing to Immuno-Informatics and Capsid Structure Modeling

Autor: Temitope O. C. Faleye, Peter Skidmore, Amir Elyaderani, Sangeet Adhikari, Nicole Kaiser, Abriana Smith, Allan Yanez, Tyler Perleberg, Erin M. Driver, Rolf U. Halden, Arvind Varsani, Matthew Scotch

Publikováno v: Viruses, Vol 16, Iss 8, p 1188 (2024)

The SARS-CoV-2 pandemic resulted in a scale-up of viral genomic surveillance globally. However, the wet lab constraints (economic, infrastructural, and personnel) of translating novel virus variant sequence information to meaningful immunological and

Externí odkaz: https://doaj.org/article/8220dd43d53e495094c7bd57428abd45

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Akademický článek

Detection of human, porcine and canine picornaviruses in municipal sewage sludge using pan-enterovirus amplicon-based long-read Illumina sequencing

Autor: Temitope O. C. Faleye, Erin M. Driver, Devin A. Bowes, Rochelle H. Holm, Daymond Talley, Ray Yeager, Aruni Bhatnagar, Ted Smith, Arvind Varsani, Rolf U. Halden, Matthew Scotch

Publikováno v: Emerging Microbes and Infections, Vol 11, Iss 1, Pp 1339-1342 (2022)

We describe the successful detection of human, porcine and canine picornaviruses (CanPV) in sewage sludge (at each stage of treatment) from Louisville, Kentucky, USA, using Pan-enterovirus amplicon-based long-read Illumina sequencing. Based on public

Externí odkaz: https://doaj.org/article/43700121a2c7440ba24b5302ead0a76a

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Akademický článek

Three years of wastewater surveillance for new psychoactive substances from 16 countries

Publikováno v: Water Research X, Vol 19, Iss , Pp 100179- (2023)

The proliferation of new psychoactive substances (NPS) over recent years has made their surveillance complex. The analysis of raw municipal influent wastewater can allow a broader insight into community consumption patterns of NPS. This study examine

Externí odkaz: https://doaj.org/article/9e1d9456c558413aad9017bb26905ea4

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Akademický článek

Baseline Sequencing Surveillance of Public Clinical Testing, Hospitals, and Community Wastewater Reveals Rapid Emergence of SARS-CoV-2 Omicron Variant of Concern in Arizona, USA

Publikováno v: mBio, Vol 14, Iss 1 (2023)

ABSTRACT The adaptive evolution of SARS-CoV-2 variants is driven by selection for increased viral fitness in transmissibility and immune evasion. Understanding the dynamics of how an emergent variant sweeps across populations can better inform public

Externí odkaz: https://doaj.org/article/d5fa78427a654239b49a1e06001b5a60

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Akademický článek

Use of hemagglutinin and neuraminidase amplicon-based high-throughput sequencing with variant analysis to detect co-infection and resolve identical consensus sequences of seasonal influenza in a university setting

Autor: Temitope O. C. Faleye, Deborah Adams, Sangeet Adhikari, Helen Sandrolini, Rolf U. Halden, Arvind Varsani, Matthew Scotch

Publikováno v: BMC Infectious Diseases, Vol 21, Iss 1, Pp 1-12 (2021)

Abstract Background Local transmission of seasonal influenza viruses (IVs) can be difficult to resolve. Here, we study if coupling high-throughput sequencing (HTS) of hemagglutinin (HA) and neuraminidase (NA) genes with variant analysis can resolve s

Externí odkaz: https://doaj.org/article/b0b8fb68ac544fd484c26e431852059c

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Akademický článek

Evaluating the effect of spaceflight on the host–pathogen interaction between human intestinal epithelial cells and Salmonella Typhimurium

Publikováno v: npj Microgravity, Vol 7, Iss 1, Pp 1-10 (2021)

Abstract Spaceflight uniquely alters the physiology of both human cells and microbial pathogens, stimulating cellular and molecular changes directly relevant to infectious disease. However, the influence of this environment on host–pathogen interac

Externí odkaz: https://doaj.org/article/0a444f5908f9404283b41f24e25ddf2d

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Akademický článek

Opportunities and limits of wastewater-based epidemiology for tracking global health and attainment of UN sustainable development goals

Autor: Sangeet Adhikari, Rolf U. Halden

Publikováno v: Environment International, Vol 163, Iss , Pp 107217- (2022)

Wastewater-based epidemiology (WBE) emerged as a powerful, actionable health management tool during the COVID-19 pandemic. Hypothesizing future uses, we explored its potential for real-time, tracking of progress in attaining United Nations Sustainabl

Externí odkaz: https://doaj.org/article/2b72eeec71d84d71a5971c9cf5eaad76

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