Zobrazeno 1 - 10
of 132
pro vyhledávání: '"Rolf T Urbanus"'
Autor:
Marjon H Cnossen, Karin Fijnvandraat, Ron Mathot, Antoine C G Egberts, Rolf T Urbanus, Anouk Donners, Konrad van der Zwet, Ilmar Kruis, Roger Schutgens, Kathelijn Fischer
Publikováno v:
BMJ Open, Vol 13, Iss 6 (2023)
Introduction Emicizumab effectively prevents bleeding in people with haemophilia A (PwHA), but is a burden for national healthcare budgets and consequently may limit access. According to the drug label, dosing of emicizumab is based on body weight wi
Externí odkaz:
https://doaj.org/article/f47c9a04101c40b8914e5a78633418b0
Autor:
Carolina De Marco Verissimo, Heather L Jewhurst, Irina G Tikhonova, Rolf T Urbanus, Aaron G Maule, John P Dalton, Krystyna Cwiklinski
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 8, p e0008510 (2020)
Serine protease inhibitors (serpins) regulate proteolytic events within diverse biological processes, including digestion, coagulation, inflammation and immune responses. The presence of serpins in Fasciola hepatica excretory-secretory products indic
Externí odkaz:
https://doaj.org/article/889313ea57b844b6a4f283fbc357103b
Autor:
Silvita Fitri Riswari, Rahajeng N Tunjungputri, Vesla Kullaya, Fadel M Garishah, Gloria S R Utari, Nur Farhanah, Gijs J Overheul, Bachti Alisjahbana, M Hussein Gasem, Rolf T Urbanus, Philip G de Groot, Dirk J Lefeber, Ronald P van Rij, Andre van der Ven, Quirijn de Mast
Publikováno v:
PLoS Pathogens, Vol 15, Iss 3, p e1007500 (2019)
Thrombocytopenia and platelet dysfunction are commonly observed in patients with dengue virus (DENV) infection and may contribute to complications such as bleeding and plasma leakage. The etiology of dengue-associated thrombocytopenia is multifactori
Externí odkaz:
https://doaj.org/article/4d880d6ee6de4d999d6e2391022c7045
Autor:
Rahajeng N Tunjungputri, Muhammad Hussein Gasem, Willemijn van der Does, Pandu H Sasongko, Bambang Isbandrio, Rolf T Urbanus, Philip G de Groot, Andre van der Ven, Quirijn de Mast
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005915 (2017)
Severe leptospirosis is frequently complicated by a hemorrhagic diathesis, of which the pathogenesis is still largely unknown. Thrombocytopenia is common, but often not to the degree that spontaneous bleeding is expected. We hypothesized that the hem
Externí odkaz:
https://doaj.org/article/3aabf7a21cb841d8ac44c277f4ce3165
Autor:
Minka Zivkovic, Elisabeth Pols - van Veen, Vossa van der Vegte, Silvie A.E. Sebastian, Annick S. de Moor, Suzanne J.A. Korporaal, Roger E.G. Schutgens, Rolf T. Urbanus, Erik Beckers, Michiel Coppens, Jeroen Eikenboom, Louise Hooimeijer, Gerard Jansen, Roger Schutgens, Rolf Urbanus, Emile van den Akker, Wala Al Arashi, Ryanne Arisz, Lieke Baas, Ruben Bierings, Maartje van den Biggelaar, Johan Boender, Anske van der Bom, Mettine Bos, Martijn Brands, Annelien Bredenoord, Laura Bukkems, Lex Burdorf, Jessica Del Castillo Alferez, Michael Cloesmeijer, Marjon Cnossen, Mariëtte Driessens, Karin Fijnvandraat, Kathelijn Fischer, Geertje Goedhart, Tine Goedhart, Samantha Gouw, Rieke van der Graaf, Masja de Haas, Lotte Haverman, Jan Hazelzet, Shannon van Hoorn, Elise Huisman, Nathalie Jansen, Alexander Janssen, Sean de Jong, Sjoerd Koopman, Marieke Kruip, Sebastiaan Laan, Frank Leebeek, Nikki van Leeuwen, Hester Lingsma, Moniek de Maat, Ron Mathôt, Felix van der Meer, Karina Meijer, Sander Meijer, Stephan Meijer, Iris van Moort, Caroline Mussert, Hans Kristian Ploos van Amstel, Suzanne Polinder, Diaz Prameyllawati, Simone Reitsma, Eliza Roest, Lorenzo Romano, Saskia Schols, Carin Uyl, Jan Voorberg, Huan Zhang
Publikováno v:
Research and Practice in Thrombosis and Haemostasis, Vol 8, Iss 7, Pp 102582- (2024)
Background: Glycoprotein (GP)VI is a platelet-specific collagen receptor required for platelet activation during hemostasis. Platelet reactivity toward collagen is routinely assessed during diagnostic workup of platelet disorders. GPVI can be activat
Externí odkaz:
https://doaj.org/article/0ff9e6640dac449daeff9b624d1422ef
Autor:
Mirjam M Mebius, Perry J J van Genderen, Rolf T Urbanus, Aloysius G M Tielens, Philip G de Groot, Jaap J van Hellemond
Publikováno v:
PLoS Pathogens, Vol 9, Iss 12, p e1003781 (2013)
Schistosomes, parasitic flatworms that cause the tropical disease schistosomiasis, are still a threat. They are responsible for 200 million infections worldwide and an estimated 280,000 deaths annually in sub-Saharan Africa alone. The adult parasites
Externí odkaz:
https://doaj.org/article/a3cdc26c3e0b4867a5cfd9d1b54fd5eb
Autor:
Wobke E.M. van Dijk, Geke C. Poolen, Albert Huisman, Harry R. Koene, Rob Fijnheer, Noortje Thielen, Esther R. van Bladel, Karin P.M. van Galen, Roger E.G. Schutgens, Rolf T. Urbanus
Publikováno v:
Journal of Thrombosis and Haemostasis. 21:1020-1031
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7398de9807c825546ec867d7512115f
https://doi.org/10.1016/j.jtha.2022.11.039
https://doi.org/10.1016/j.jtha.2022.11.039
Autor:
Omayra C.D. Liesdek, Rolf T. Urbanus, Steven de Maat, Linda M. de Heer, Faiz Z. Ramjankhan, Silvie A.E. Sebastian, Albert Huisman, Nicolaas de Jonge, Aryan Vink, Kathelijn Fischer, Coen Maas, Willem J.L. Suyker, Roger E.G. Schutgens
Publikováno v:
ASAIO Journal. 69:438-444
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::96e13caeb58b1c0233b89efc370d505c
https://doi.org/10.1097/mat.0000000000001855
https://doi.org/10.1097/mat.0000000000001855
Autor:
Awital Bar Barroeta, J. Arnoud Marquart, Kamran Bakhtiari, Alexander B. Meijer, Rolf T. Urbanus, Joost C.M. Meijers
Publikováno v:
Journal of thrombosis and haemostasis, 20(11), 2538-2549. Wiley-Blackwell
Background: Factor XI (FXI) is a promising target for novel anticoagulants because it shows a strong relation to thromboembolic diseases, while fulfilling a mostly supportive role in hemostasis. Anticoagulants targeting FXI could therefore reduce the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::710c11d4770cac1322b4a020446d47e3
https://doi.org/10.1111/jth.15815
https://doi.org/10.1111/jth.15815
Autor:
Tessa Noordermeer, Ivar van Asten, Roger E. G. Schutgens, Anke J. Lakerveld, Cornelis A. Koekman, Kay Y. Hage, Silvie A. E. Sebastian, Albert Huisman, Dave J. van den Heuvel, Hans C. Gerritsen, Suzanne J. A. Korporaal, Marc Bierings, Jasper J. van der Smagt, Mariëlle E. van Gijn, Rolf T. Urbanus
Publikováno v:
Blood Advances. 6:3347-3351
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bba843e5a94fe64ea785e2cad1bad002
https://doi.org/10.1182/bloodadvances.2021006830
https://doi.org/10.1182/bloodadvances.2021006830