Zobrazeno 1 - 10
of 47
pro vyhledávání: '"Rolf O. Karlstrom"'
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract Techniques used to clear biological tissue for fluorescence microscopy are essential to connect anatomical principles at levels ranging from subcellular to the whole animal. Here we report a simple and straightforward approach to efficiently
Externí odkaz:
https://doaj.org/article/c1b507e37c8446c3b4426afebbbe9637
Autor:
Ira Male, Dina Navon, Benjamin Aaronson, Rolf O. Karlstrom, R. Craig Albertson, Emily R. Tetrault
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance Phenotypic plasticity has emerged as an important concept in evolutionary biology. It is thought to contribute to an organism’s ability to adapt to environmental change within a single generation, which may facilitate survival and incr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::984787c77e5a3041f0f3c7bc1f6b0706
http://europepmc.org/articles/PMC7431006
http://europepmc.org/articles/PMC7431006
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Techniques used to clear biological tissue for fluorescence microscopy are essential to connect anatomical principles at levels ranging from subcellular to the whole animal. Here we report a simple and straightforward approach to efficiently render o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c4a2792f36e7aaf321636ab45024414
https://doi.org/10.21203/rs.3.rs-213122/v1
https://doi.org/10.21203/rs.3.rs-213122/v1
Publikováno v:
Endocrinology. 158:2774-2782
Low thyroid hormone (TH) conditions caused by a variety of prenatal and perinatal problems have been shown to alter postnatal regulatory thyrotropin (TSH) responsiveness to TH in humans and rodents. The mechanisms underlying this pituitary TH resista
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cc9c2f0b6447209921652adce2541ec
https://doi.org/10.1210/en.2016-1935
https://doi.org/10.1210/en.2016-1935
Here we report a strategy to efficiently render opaque biological tissues transparent and demonstrate that this approach can be modified to rapidly label intact samples with antibodies for large volume fluorescence microscopy. This strategy applies a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fb8ae9aad193f68e1fbc96e7424fa09
https://doi.org/10.1101/819292
https://doi.org/10.1101/819292
Autor:
Rolf O. Karlstrom, Matthew D. Loring, Ira Male, Rita R. Fagan, Alyssa Lutservitz, A. Tuba Ozacar, Veronica A. Pace, Meng-Chieh Shen, Christine Devine
While neurogenesis in the adult hypothalamus is now known to be essential for proper function, the cell-cell signaling events that regulate neurogenesis in this evolutionarily conserved brain region remain poorly understood. Here we show that Hedgeho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bbd2380edacf4cdffbcd4353e927d49
https://doi.org/10.1101/740613
https://doi.org/10.1101/740613
Autor:
Rita R. Fagan, Christine A. Devine, A. Tuba Ozacar, Matthew D. Loring, Alyssa Lutservitz, Ira Male, Veronica A. Pace, Rolf O. Karlstrom, Grace E. Lawson, Meng-Chieh Shen
Publikováno v:
eNeuro
Visual Abstract
Neurogenesis is now known to play a role in adult hypothalamic function, yet the cell-cell mechanisms regulating this neurogenesis remain poorly understood. Here, we show that Hedgehog (Hh)/Gli signaling positively regulates hypo
Neurogenesis is now known to play a role in adult hypothalamic function, yet the cell-cell mechanisms regulating this neurogenesis remain poorly understood. Here, we show that Hedgehog (Hh)/Gli signaling positively regulates hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d49a2aaed40a0d721a9e95e4aa69ff
https://doi.org/10.1523/eneuro.0226-20.2020
https://doi.org/10.1523/eneuro.0226-20.2020
Publikováno v:
Molecular and Cellular Endocrinology. 369:98-106
Prolactin (PRL) is a well-known regulator of ion and water transport within osmoregulatory tissues across vertebrate species, yet how PRL acts on some of its target tissues remains poorly understood. Using zebrafish as a model, we show that ionocytes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b4050084024380c476350252c76bd54
https://doi.org/10.1016/j.mce.2013.01.021
https://doi.org/10.1016/j.mce.2013.01.021
Autor:
Rolf O. Karlstrom, Jhumku D. Kohtz, Marcey Osgood, A. Tuba Ozacar, Jochebed Pink, Crina Boeras, Jeanne E. Thomas, Meng Chieh Shen
Publikováno v:
Developmental Dynamics. 242:539-549
Background: Hedgehog (Hh) signaling is required for embryogenesis and continues to play key roles postembryonically in many tissues, influencing growth, stem cell proliferation, and tumorigenesis. Systems for conditional regulation of Hh signaling fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f3c36ab2a599d9d5bdf3d4beddb60f94
https://doi.org/10.1002/dvdy.23955
https://doi.org/10.1002/dvdy.23955
Autor:
Kenneth D. Poss, Matthew Gemberling, Wen-Yee Choi, Jennifer E. Holdway, Rolf O. Karlstrom, Jinhu Wang, Meng-Chieh Shen
Publikováno v:
Development. 140:660-666
Adult mammalian cardiomyocytes have little capacity to proliferate in response to injury, a deficiency that underlies the poor regenerative ability of human hearts after myocardial infarction. By contrast, zebrafish regenerate heart muscle after trau
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd6a2b2ba53fe36713437ea496f92bff
https://doi.org/10.1242/dev.088526
https://doi.org/10.1242/dev.088526