Design of ATP Competitive Specific Inhibitors of Protein Kinases Using Template Modeling

Autor: Madhusudan, Charles A. Ellis, Janusz M. Sowadski, Rolf Karlsson

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::dbbc68e477f242bbabfd8c733ab4bfdf
https://doi.org/10.1201/9780203738023-8

Heterozygous carriers in the relatives of a case of phenylketonuria

Autor: Risto Kääriäinen, Rolf Karlsson

Publikováno v: Hereditas. 75:109-118

The 10 adult relatives of a known case of phenylketonuria (PKU) were analysed with the criterion groups of normal controls (N = 24) and heterozygotes (N = 16), with values of fasting and loading phenylalanine (100 mg/kg of body weight) and tyrosine t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::648ea622476606ae7ee4dda7d00d0ddf
https://doi.org/10.1111/j.1601-5223.1973.tb01147.x

Evaluation of computational fluid dynamic methods for reactor safety analysis (ECORA)

Autor: D. Bestion, Yury Egorov, H. Paillere, S. Willemsen, S. Pigny, M. Heitsch, M. Scheuerer, B. Hemström, Rolf Karlsson, Brian L. Smith, Michele Andreani, A. Martin, Eckhard Krepper, Florian R. Menter, G. Kimber, Mats Henriksson, Ismo Karppinen, I. Toth, M. Boucker, P. Muhlbauer

Publikováno v: Scheuerer, M, Heitsch, M, Menter, F, Egorov, Y, Toth, I, Bestion, D, Pigny, S, Paillere, H, Martin, A, Boucker, M, Krepper, E, Willemsen, S, Muhlbauer, P, Andreani, M, Smith, B, Karlsson, R, Henriksson, M, Hemstrom, B, Karppinen, I & Kimber, G 2005, ' Evaluation of computational fluid dynamic methods for reactor safety analysis (ECORA) ', Nuclear Engineering and Design, vol. 235, no. 2-4, pp. 359-368 . https://doi.org/10.1016/j.nucengdes.2004.08.049
Nuclear Engineering and Design 235(2005)2-4, 359-368

The objective of the ECORA project is the evaluation of computational fluid dynamics (CFD) software for reactor safety applications, resulting in best practice guidelines (BPG) for an efficient use of CFD for reactor safety problems. The project sche

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf793aa37b22de9bd93ba99fb9fe69e8
https://doi.org/10.1016/j.nucengdes.2004.08.049

An experimental study of a two-dimensional plane turbulent wall jet

Autor: J. G. Eriksson, Persson Johan, Rolf Karlsson

Publikováno v: Experiments in Fluids. 25:50-60

Laser-Doppler measurements were conducted in a plane turbulent wall jet at a Reynolds number based on inlet velocity, Re 0, of 9600. The initial development as well as the fully developed flow was studied. Special attention was given to the near-wall

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9395da36f1b65228724f527be97c70c0
https://doi.org/10.1007/s003480050207

Structure of the mammalian catalytic subunit of cAMP-dependent protein kinase and an inhibitor peptide displays an open conformation

Autor: Susan S. Taylor, Rolf Karlsson, Janusz M. Sowadski, Jianhua Zheng, Nguyen-Huu Xuong

Publikováno v: Acta Crystallographica Section D Biological Crystallography. 49:381-388

The crystal structure of a binary complex of the porcine heart catalytic (C) subunit of cAMP-dependent protein kinase (space group P4(1)32; a = 171.5 A) complexed with a di-iodinated peptide inhibitor, PKI(5-24), has been solved and refined to 2.9 A

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d8242454d042a4c08f3adff95120a9
https://doi.org/10.1107/s0907444993002306