Zobrazeno 1 - 10
of 48
pro vyhledávání: '"Rolf Jakobi"'
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 11, Iss 3, Pp 286-297 (2009)
p21-Activated kinase 2 (PAK-2) seems to be a regulatory switch between cell survival and cell death signaling. We have shown previously that activation of full-length PAK-2 by Rac or Cdc42 stimulates cell survival, whereas caspase activation of PAK-2
Externí odkaz:
https://doaj.org/article/1c39801514ec4dcbaa5e31ccc2c898e9
Publikováno v:
BioTechniques, Vol 33, Iss 6, Pp 1218-1222 (2002)
Externí odkaz:
https://doaj.org/article/e734ac23800f40b0abc106782cac1f49
Publikováno v:
BioTechniques, Vol 30, Iss 3, Pp 476-482 (2001)
Externí odkaz:
https://doaj.org/article/a3671a2b93a5432f83f4fd5de031eaab
Publikováno v:
BioPhysical Economics and Resource Quality. 1
The gradual depletion of low cost (or “high grade”) mineral ores is generating increasing extractive costs and diminishing economic returns. The market reacts to this situation either with high prices, which depress demand, or with very low price
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8464507df9bbc33811eaab6a4e96a852
https://doi.org/10.1007/s41247-016-0004-x
https://doi.org/10.1007/s41247-016-0004-x
Publikováno v:
Journal of Cell Death, Vol 2010, Iss 3, Pp 23-32 (2010)
p21-activated kinase 2 (PAK-2) appears to have a dual function in the regulation of cell survival and cell death. Activation of full-length PAK-2 by the p21 G-proteins Rac or Cdc42 stimulates cell survival. However, PAK-2 is unique among the PAK fami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::d47a4497fb22409c16818c73fa4f2378
http://la-press.com/caspase-activation-of-p21-activated-kinase-2-occurs-during--cisplatin--a2021
http://la-press.com/caspase-activation-of-p21-activated-kinase-2-occurs-during--cisplatin--a2021
Autor:
Jolinda A. Traugh, Rolf Jakobi
Publikováno v:
European Journal of Biochemistry. 230:1111-1117
Casein kinase II exists in vivo as an active holoenzyme consisting of catalytic alpha and/or alpha' and regulatory beta subunits, which form a tetrameric structure of alpha 2 beta 2. Unlike most other protein kinases, casein kinase II uses both ATP a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::85b129a65fa590a2fe58982f96b38aaf
https://doi.org/10.1111/j.1432-1033.1995.1111g.x
https://doi.org/10.1111/j.1432-1033.1995.1111g.x
Publikováno v:
Cancer Research. 66:11700-11708
Cyclooxygenase-2 (COX-2) represents an important target for treatment and prevention of colorectal cancer. Although COX-2 signaling is implicated in promoting tumor cell growth and invasion, the molecular mechanisms that mediate these processes are l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cd0bb13966eedbc6fff7056602f01d9
https://doi.org/10.1158/0008-5472.can-06-1818
https://doi.org/10.1158/0008-5472.can-06-1818
Autor:
Rolf Jakobi
Publikováno v:
Drug Resistance Updates. 7:11-17
Subcellular localization and targeting of proteins play important roles in signal transduction pathways that regulate cell survival and programmed cell death. The regulation of cell survival and cell death requires translocation of many anti- and pro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ed32be89e37dee3567caddec916c526
https://doi.org/10.1016/j.drup.2004.01.001
https://doi.org/10.1016/j.drup.2004.01.001
Publikováno v:
Journal of Biological Chemistry. 278:38675-38685
p21-activated protein kinases (PAKs) are a family of serine/threonine protein kinases that are activated by binding of the p21 G proteins Cdc42 or Rac. The ubiquitous PAK-2 (gamma-PAK) is unique among the PAK isoforms because it is also activated thr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::784db4f197fe2c5993de75c9f20fb55a
https://doi.org/10.1074/jbc.m306494200
https://doi.org/10.1074/jbc.m306494200