Zobrazeno 1 - 10 of 89 pro vyhledávání: '"Rolf Jaggi"'
1
Akademický článek
Molecular characterization of breast cancer cell pools with normal or reduced ability to respond to progesterone: a study based on RNA-seq
Autor: Mariana Bustamante Eduardo, Irene Keller, Nathalie Schuster, Stefan Aebi, Rolf Jaggi
Publikováno v: Journal of Genetic Engineering and Biotechnology, Vol 21, Iss 1, Pp 1-12 (2023)
Abstract Background About one-third of patients with estrogen receptor alpha (ERα)-positive breast cancer have tumors which are progesterone receptor (PR) negative. PR is an important prognostic factor in breast cancer. Patients with ERα-positive/P
Externí odkaz: https://doaj.org/article/6e39a48d35504bc79ba51ef2d9ae9919
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2
Akademický článek
Characterization of molecular scores and gene expression signatures in primary breast cancer, local recurrences and brain metastases
Autor: Mariana Bustamante Eduardo, Vlad Popovici, Sara Imboden, Stefan Aebi, Nadja Ballabio, Hans Jörg Altermatt, Andreas Günthert, Rolf Jaggi
Publikováno v: BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Abstract Background Breast cancer is a leading cause of cancer-related death in women worldwide. Despite extensive studies in all areas of basic, clinical and applied research, accurate prognosis remains elusive, thus leading to overtreatment of many
Externí odkaz: https://doaj.org/article/06e512fcaf37410a8cb7a4f963a11cc2
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5
Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre- and post-treatment biopsies in the multi-center SAKK19/09 study
Autor: M L Amrein, S Savic-Prince, Adrian F. Ochsenbein, Michael A. Amrein, Elias D. Bührer, Rolf Jaggi, Sacha I. Rothschild, Lukas Bubendorf, Qiyu Li, Carsten Riether, O. Gautschi
Publikováno v: Amrein, M. A.; Bührer, E. D.; Amrein, M. L.; Li, Q.; Rothschild, S.; Riether, C.; Jaggi, R.; Savic-Prince, S.; Bubendorf, L.; Gautschi, O.; Ochsenbein, A. (2021). Chemotherapy negatively impacts the tumor immune microenvironment in NSCLC: an analysis of pre-and post-treatment biopsies in the multi-center SAKK19/09 study. Cancer immunology, immunotherapy : CII, 70(2), pp. 405-415. Springer 10.1007/s00262-020-02688-4
Cancer Immunology, Immunotherapy
Background Over the past few years, immune checkpoint inhibitors have changed the therapeutic landscape of non-small-cell lung cancer (NSCLC). Response to immune checkpoint inhibitors correlates with a pre-existing anti-tumoral immune response. Check
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c2a4c07e703a7e94e7638a8c438fa03
https://doi.org/10.1007/s00262-020-02688-4
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6
Akademický článek
Hepatic gene expression profile in mice perorally infected with Echinococcus multilocularis eggs.
Autor: Bruno Gottstein, Matthias Wittwer, Marc Schild, Michael Merli, Stephen L Leib, Norbert Müller, Joachim Müller, Rolf Jaggi
Publikováno v: PLoS ONE, Vol 5, Iss 4, p e9779 (2010)
BACKGROUND: Alveolar echinococcosis (AE) is a severe chronic hepatic parasitic disease currently emerging in central and eastern Europe. Untreated AE presents a high mortality (>90%) due to a severe hepatic destruction as a result of parasitic metace
Externí odkaz: https://doaj.org/article/ee40756742bd49be95fce0e47440f68c
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7
Characterization of molecular scores and gene expression signatures in primary breast cancer, local recurrences and brain metastases
Autor: Andreas R. Günthert, Rolf Jaggi, Mariana Bustamante Eduardo, Hans Jörg Altermatt, Nadja Ballabio, Sara Imboden, Stefan Aebi, Vlad Popovici
Publikováno v: BMC Cancer
Bustamante Eduardo, Mariana; Popovici, Vlad; Imboden, Sara; Aebi, Stefan; Ballabio, Nadja; Altermatt, Hans Jörg; Günthert, Andreas; Jaggi, Rolf (2019). Characterization of molecular scores and gene expression signatures in primary breast cancer, local recurrences and brain metastases. BMC cancer, 19(1), p. 549. BioMed Central 10.1186/s12885-019-5752-8
BMC Cancer, Vol 19, Iss 1, Pp 1-14 (2019)
Background Breast cancer is a leading cause of cancer-related death in women worldwide. Despite extensive studies in all areas of basic, clinical and applied research, accurate prognosis remains elusive, thus leading to overtreatment of many patients
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c210cb1ea79f457d2c497fe1647a024
http://europepmc.org/articles/PMC6556009
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8
Joint analysis of histopathology image features and gene expression in breast cancer
Autor: Daniel Schwarz, Josef Feit, Vlad Popovici, Lenka Čápková, Ladislav Dušek, Rolf Jaggi, Eva Budinská
Publikováno v: BMC Bioinformatics
Popovici, Vlad; Budinská, Eva; Čápková, Lenka; Schwarz, Daniel; Dušek, Ladislav; Feit, Josef; Jaggi, Rolf (2016). Joint analysis of histopathology image features and gene expression in breast cancer. BMC bioinformatics, 17(1), p. 209. BioMed Central 10.1186/s12859-016-1072-z
Background Genomics and proteomics are nowadays the dominant techniques for novel biomarker discovery. However, histopathology images contain a wealth of information related to the tumor histology, morphology and tumor-host interactions that is not a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::47b4808fe10531f063fde856ddf57b6f
http://europepmc.org/articles/PMC4864935
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9
MicroRNA-381 Represses ID1 and is Deregulated in Lung Adenocarcinoma
Autor: Mathias Gugger, Sacha I. Rothschild, Rolf Jaggi, Oliver Gautschi, Mario P. Tschan, Martin F. Fey
Publikováno v: Journal of Thoracic Oncology. 7:1069-1077
Introduction: MicroRNAs are small, noncoding RNAs that suppress gene expression by binding to the 3' untranslated region (UTR) and thereby repress translation or decrease messenger RNA stability. Inhibitor of differentiation 1 (ID1) is a putative ste
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73747652eccaf4d0e998c70a119dbcf7
https://doi.org/10.1097/jto.0b013e31824fe976
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10
MicroRNA-29b is involved in the Src-ID1 signaling pathway and is dysregulated in human lung adenocarcinoma
Autor: Oliver Gautschi, Mario P. Tschan, Elena A. Federzoni, Rolf Jaggi, Martin F. Fey, Matthias Gugger, Sacha I. Rothschild
Publikováno v: Oncogene. 31:4221-4232
The c-Src kinase regulates cancer cell invasion through inhibitor of DNA binding/differentiation 1 (ID1). Src and ID1 are frequently overexpressed in human lung adenocarcinoma. The current study aimed at identifying microRNAs (miRNAs) involved in the
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e114c7e3690e078a7f05ffdf1c9a8f
https://doi.org/10.1038/onc.2011.578
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