Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Rolf Horlein"'
Autor:
Norbert Krass, Dieter Isert, Rolf Horlein, Fischer Gerd, Theo Wollmann, Uwe Gerlach, Ulrich Stache, Elisabeth Defoßa, Rudolf Lattrell
Publikováno v:
Liebigs Annalen. 1996:1743-1749
HR 916 K (5), the 1-(S)-(pivaloyloxy)ethyl prodrug ester of the cephalosporin cefdaloxime, exhibits a significantly higher oral bioavailability than the 1-(R) diastereomer HR 916 J. An efficient synthesis of HR 916 K was developed. The separation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7ced9b6c375c1c441b4b7c9c015448a6
https://doi.org/10.1002/jlac.199619961107
https://doi.org/10.1002/jlac.199619961107
Autor:
Klaus Fleischmann, H. Jendralla, Christian Lefebvre, Theo Wollmann, Walter Dr. Dürckheimer, Winfried Hertzsch, Rolf Horlein, Friedhelm Adam, Jean-Michel Roul, Philippe Mackiewicz
Publikováno v:
Liebigs Annalen. 1996:1735-1741
An efficient synthesis of HR 916 B (4), the orally active 1-(RS)-(pivaloyloxy)ethyl prodrug ester of the cephalosporin cefdaloxime, was developed and applied on a multi-kg scale. AMCA (8) was prepared by exchange of the acetoxy group of fermentation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b82029316690f1ae31dbfd54778344a5
https://doi.org/10.1002/jlac.199619961106
https://doi.org/10.1002/jlac.199619961106