Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rolf Hilfiker"'
Publikováno v:
CHIMIA, Vol 55, Iss 9 (2001)
The average molar mass of active substances in crop protection as well as in pharmaceuticals has grown almost tenfold in the last century. In general, large molar masses are a drawback when looking at bioavailability. There are several strategies to
Externí odkaz:
https://doaj.org/article/178544fe68484522a6542a156c1d8567
Publikováno v:
Crystal Growth & Design
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ccb21104756e7fd47a81ea2dbefadb71
Autor:
Rolf Hilfiker, Markus von Raumer
'Polymorphism in the Pharmaceutical Industry - Solid Form and Drug Development'highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus on quality by design (QbD) concepts. It covers all important issues by way of cas
Publikováno v:
Polymorphism in the Pharmaceutical Industry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a69aa1902f5b656eeaf060ba725595a
https://doi.org/10.1002/9783527697847.ch14
https://doi.org/10.1002/9783527697847.ch14
Autor:
Rolf Hilfiker, Markus Von Raumer
Publikováno v:
Polymorphism in the Pharmaceutical Industry
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5435c6a8779aa608632dffdc1a2b22d
https://doi.org/10.1002/9783527697847.ch1
https://doi.org/10.1002/9783527697847.ch1
Autor:
Rolf Hilfiker
Publikováno v:
Crystallization
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::38a66df9a7cc7bcc1ac47b19db19f35b
https://doi.org/10.1002/9783527650323.ch5
https://doi.org/10.1002/9783527650323.ch5
Autor:
Rolf Hilfiker
Publikováno v:
Crystallization: Basic Concepts and Industrial Applications
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07f5dcb1a2714a32f937d85b87931d0b
https://doi.org/10.1002/9783527650323.ch8
https://doi.org/10.1002/9783527650323.ch8
Autor:
Timo Rager, Rolf Hilfiker
Publikováno v:
Crystal Growth & Design. 10:3237-3241
Solvent mixtures can be used to thermodynamically suppress solvate formation as a competing reaction in solution-based cocrystallization experiments. This has been demonstrated successfully for the cocrystallization of carbamazepine and saccharin in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb676f2ab7700647e57de0d6473a44b7
https://doi.org/10.1021/cg100361y
https://doi.org/10.1021/cg100361y
Autor:
Rolf Hilfiker, Timo Rager
Publikováno v:
Zeitschrift für Physikalische Chemie. 223:793-813
The topology of ternary phase diagrams of systems that are forming salts, cocrystals, solvates, or hydrates is discussed based on a simple mathematical model. The considerations include the thermodynamic stability of the multi-component crystal relat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::870803812cf11028441b2a10848c6ab0
https://doi.org/10.1524/zpch.2009.5454
https://doi.org/10.1524/zpch.2009.5454
Publikováno v:
Crystal Growth & Design. 9:2220-2228
We report the synthesis, crystal structures, and basic physicochemical properties of six co-crystals of piracetam. Co-crystals of piracetam with l-tartaric acid, with citric acid in a 1:1 and 3:2 ratio, with racemic mandelic acid, and with l-mandelic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c7957fdbcd4c53b960593567abf0c20
https://doi.org/10.1021/cg800942n
https://doi.org/10.1021/cg800942n