Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Rolf Harkes"'
Autor:
Rolf Harkes, Olga Kukk, Sravasti Mukherjee, Jeffrey Klarenbeek, Bram van den Broek, Kees Jalink
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Fluorescence Lifetime Imaging (FLIM) is an intrinsically quantitative method to screen for protein–protein interactions and is frequently used to record the outcome of signal transduction events. With new highly sensitive and photon effici
Externí odkaz:
https://doaj.org/article/fb0e1af6ef0d4af28dabea59f40f525b
Autor:
Stacey E. P. Joosten, Marius Wellenstein, Rutger Koornstra, Annelot van Rossum, Joyce Sanders, Vincent van der Noort, Maria C. Ferrandez, Rolf Harkes, Ingrid A. M. Mandjes, Hilde Rosing, Alwin Huitema, Jos H. Beijnen, Jelle Wesseling, Paul J. van Diest, Hugo M. Horlings, Sabine C. Linn, Wilbert Zwart
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
Abstract Window studies are gaining traction to assess (molecular) changes in short timeframes. Decreased tumor cell positivity for the proliferation marker Ki67 is often used as a proxy for treatment response. Immunohistochemistry (IHC)-based Ki67 o
Externí odkaz:
https://doaj.org/article/d14fa82c2abe4ab4ace6a27f694de818
Autor:
Mihaela M Apetri, Rolf Harkes, Vinod Subramaniam, Gerard W Canters, Thomas Schmidt, Thijs J Aartsma
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153020 (2016)
Aggregation of α-synuclein has been linked to both familial and sporadic Parkinson's disease. Recent studies suggest that α-synuclein aggregates may spread from cell to cell and raise questions about the propagation of neurodegeneration. While cont
Externí odkaz:
https://doaj.org/article/1a54ddfcb0ec41d7888d3f41e5d88474
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0141080 (2015)
Single-molecule imaging of proteins in a 2D environment like membranes has been frequently used to extract diffusive properties of multiple fractions of receptors. In a 3D environment the apparent fractions however change with observation time due to
Externí odkaz:
https://doaj.org/article/1b3e82b5401f4da58ca8aeb770bf4edb
Publikováno v:
Journal of Chemical Physics, 156(8), 1-13
In cell–matrix adhesions, integrin receptors and associated proteins provide a dynamic coupling of the extracellular matrix (ECM) to the cytoskeleton. This allows bidirectional transmission of forces between the ECM and the cytoskeleton, which tune
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::214293a0a132c8962d87e2f5584590cd
https://hdl.handle.net/1887/3279368
https://hdl.handle.net/1887/3279368
Autor:
Rutger H. T. Koornstra, Alwin D. R. Huitema, Marius Wellenstein, Maria C. Ferrandez, Rolf Harkes, Jos H. Beijnen, Vincent van der Noort, Stacey E. P. Joosten, Paul J. van Diest, Hugo M. Horlings, Joyce Sanders, Sabine C. Linn, I.A.M. Mandjes, Hilde Rosing, Jelle Wesseling, Wilbert Zwart, Annelot van Rossum
Publikováno v:
npj Breast Cancer, Vol 7, Iss 1, Pp 1-8 (2021)
npj Breast Cancer, 7:138. Nature Publishing Group
NPJ Breast Cancer
npj Breast Cancer, 7:138. Nature Publishing Group
NPJ Breast Cancer
Window studies are gaining traction to assess (molecular) changes in short timeframes. Decreased tumor cell positivity for the proliferation marker Ki67 is often used as a proxy for treatment response. Immunohistochemistry (IHC)-based Ki67 on tissue
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d92f9621dffaa40da5e9118d7ace117d
https://doi.org/10.1038/s41523-021-00344-3
https://doi.org/10.1038/s41523-021-00344-3
In cell matrix adhesions, integrin receptors and associated proteins provide a dynamic coupling of the extracellular matrix (ECM) to the cytoskeleton. This allows bidirectional transmission of forces between the ECM and the cytoskeleton, which tunes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a185e03e2876a796171eb88001a3bb1
https://doi.org/10.1101/2021.10.29.466476
https://doi.org/10.1101/2021.10.29.466476
Autor:
Leila, Nahidiazar, Rolf, Harkes
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2350
Super Resolution (SR) microscopy has become a powerful tool to study cellular architecture at the nanometer scale. Single molecule localization microscopy (SMLM) is a method in which fluorophore labels repeatedly switch On and Off ("blink"). Their ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::5f62d1a71194f0ab86fd4d005f192950
https://pubmed.ncbi.nlm.nih.gov/34331279
https://pubmed.ncbi.nlm.nih.gov/34331279
Autor:
Rolf Harkes, Olga Kukk, Sravasti Mukherjee, Jeffrey Klarenbeek, Bram van den Broek, Kees Jalink
Fluorescence Lifetime Imaging (FLIM) is an intrinsically quantitative method to screen for protein-protein interactions and frequently used to record the outcome of signal transduction events. With new highly sensitive and photon efficient FLIM instr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa6d83b90aac3ad29da6238f59324607
https://doi.org/10.1101/2021.05.23.445328
https://doi.org/10.1101/2021.05.23.445328
Autor:
Leila Nahidiazar, Rolf Harkes
Publikováno v:
Methods in Molecular Biology ISBN: 9781071615928
Super Resolution (SR) microscopy has become a powerful tool to study cellular architecture at the nanometer scale. Single molecule localization microscopy (SMLM) is a method in which fluorophore labels repeatedly switch On and Off ("blink"). Their ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6f18e5a770b4a607aa1764563a2dc8e7
https://doi.org/10.1007/978-1-0716-1593-5_5
https://doi.org/10.1007/978-1-0716-1593-5_5