Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Rolf G. Werner"'
Autor:
Surasak Jittavisutthikul, Watee Seesuay, Jeeraphong Thanongsaksrkul, Kanyarat Thueng-in, Potjanee Srimanote, Rolf G. Werner, Wanpen Chaicumpa
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
A safe and effective direct acting anti-hepatitis C virus (HCV) agent is still needed. In this study, human single-chain variable fragments of antibody (scFvs) that bound to HCV NS3/4A protein were produced by phage display technology. The engineered
Externí odkaz:
https://doaj.org/article/705c98ce9a65459596001a1dba42a066
Autor:
Rolf G. Werner
Publikováno v:
CHIMIA, Vol 48, Iss 10 (1994)
The development of biotechnical processes is a very complex operation. It involves the creation and verification of a strong expression system, selection and characterization of an appropriate host cell, optimization of a fermentation media, design o
Externí odkaz:
https://doaj.org/article/27d3100e92424cc49630fbb55de62efe
Publikováno v:
International Journal of Medical Microbiology. 304:63-71
The Staphylococcus epidermidis derived epidermin was the first lantibiotic that has been shown to be ribosomally synthesized and posttranslationally modified. Together with gallidermin, produced by Staphylococcus gallinarum, they belong to the large
Autor:
Jiradej Manosroi, Worapaka Manosroi, T. Tangjai, Friedrich Götz, Rolf G. Werner, Aranya Manosroi
Publikováno v:
Drug Research. 63:351-356
Trans-activator of transcription (Tat) is a cell penetrating peptide which can translocate and carry macromolecular cargoes through cell membranes. This study investigated the hypoglycemic activity of orally delivered insulin - Tat mixture in alloxan
Autor:
Jiradej Manosroi, Rolf G. Werner, Aranya Manosroi, Friedrich Götz, Narinthorn Khositsuntiwong, Worapaka Manosroi
Publikováno v:
Drug Delivery. 20:10-18
Enhancement of transdermal absorption through rat skin and stability of the human tyrosinase plasmid (P) using Tat (T) and an entrapment in elastic cationic niosomes (E) were described. E (Tween61:cholesterol:DDAB at 1:1:0.5 molar ratio) were prepare
Autor:
Jiradej Manosroi, Aranya Manosroi, Narinthorn Khositsuntiwong, Friedrich Götz, Rolf G. Werner, Worapaka Manosroi
Publikováno v:
Chemical Biology & Drug Design. 80:953-960
Potent melanin production enhancement of human tyrosinase plasmid (pAH7/Tyr, P) in mouse melanoma cells (B16F10) by Tat peptide (T) and an entrapment in elastic cationic niosomes (E) was described. The E composed of Tween 61/cholesterol/dodecyl dimet
Autor:
Kanyarat Thueng-in, Potjanee Srimanote, Surasak Jittavisutthikul, Wanpen Chaicumpa, Rolf G. Werner, Jeeraphong Thanongsaksrikul, Watee Seesuay
Publikováno v:
Frontiers in Immunology, Vol 7 (2016)
Frontiers in Immunology
Frontiers in Immunology
A safe and effective direct acting anti-hepatitis C virus (HCV) agent is still needed. In this study, human single chain variable fragments of antibody (scFvs) that bound to HCV NS3/4A protein were produced by phage display technology. The engineered
Autor:
Jiradej Manosroi, Worapaka Manosroi, Mathukorn Sainakham, Theeraphong Tangjai, Aranya Manosroi, Friedrich Götz, Chanutchamon Sutthiwanjampa, Rolf G. Werner
Publikováno v:
Drug delivery. 23(8)
This study aimed to investigate the synergistic effect of trans-activator of transcription (Tat) and niosomes for the improvement of hypoglycemic activity of orally delivered human insulin. The elastic anionic niosomes composing of Tween 61/cholester
Autor:
Rolf G. Werner, Narinthorn Khositsuntiwong, Jiradej Manosroi, Friedrich Götz, Aranya Manosroi, Worapaka Manosroi
Publikováno v:
Journal of Pharmacy and Pharmacology. 64:1376-1385
Objectives Disturbance in the synthesis of tyrosinase might be one of the major causes of vitiligo. The enhancement of tyrosinase gene expression and melanin production by loading the plasmid in elastic cationic niosomes was investigated in tyrosinas
Autor:
Jürgen Beer, Rolf G. Werner, Klaus Bergemann, Aranya Manosroi, Jiradey Manosroi, Chatchai Tayapiwatana
Publikováno v:
Arzneimittelforschung. 52:60-66
Fermentation studies of batch-mode cultivation in 4-L fermenters were carried out to obtain an active recombinant DNA-derived tissue plasminogen activator (t-PA) deletion mutant, lekteplase, secreted and correctly folded from Escherichia coli. The Om