Zobrazeno 1 - 10
of 106
pro vyhledávání: '"Rolf Fendel"'
Autor:
Carlos Lamsfus Calle, Frieder Schaumburg, Thorsten Rieck, Anne Marie Nkoma Mouima, Pablo Martinez de Salazar, Saskia Breil, Johannes Behringer, Peter G. Kremsner, Benjamin Mordmüller, Rolf Fendel
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 10 (2024)
ABSTRACT Malaria rapid diagnostic tests (RDTs), which detect Plasmodium falciparum (Pf)-specific histidine-rich protein-2 (HRP2), have increasing importance for the diagnosis and control of malaria, especially also in regions where routine diagnosis
Externí odkaz:
https://doaj.org/article/3d1f53ac76db43dc855dae582fba5f08
Autor:
Anneth Tumbo, Freia-Raphaella Lorenz, Annie S.P. Yang, Stephanie Sefried, Tobias Schindler, Maximilian Mpina, Jean-Pierre Dangy, Florence A. Milando, Mohammed A. Rashid, Gloria Nyaulingo, Kamaka Ramadhani, Said Jongo, Philip L. Felgner, Yonas Abebe, B. Kim Lee Sim, L.W. Preston Church, Thomas L. Richie, Peter F. Billingsley, Tooba Murshedkar, Stephen L. Hoffman, Salim Abdulla, Peter G. Kremsner, Benjamin Mordmüller, Claudia Daubenberger, Rolf Fendel
Publikováno v:
EBioMedicine, Vol 108, Iss , Pp 105364- (2024)
Summary: Background: PfSPZ Vaccine, a promising pre-erythrocytic stage malaria vaccine candidate based on whole, radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ), has proven safe and effective in mediating sterile protection from mal
Externí odkaz:
https://doaj.org/article/608a577a935848f082781131f68893d7
Autor:
Jacqueline Wistuba-Hamprecht, Bernhard Reuter, Rolf Fendel, Stephen L Hoffman, Joseph J Campo, Philip L Felgner, Peter G Kremsner, Benjamin Mordmüller, Nico Pfeifer
Publikováno v:
PLoS Computational Biology, Vol 20, Iss 6, p e1012131 (2024)
Immunization through repeated direct venous inoculation of Plasmodium falciparum (Pf) sporozoites (PfSPZ) under chloroquine chemoprophylaxis, using the PfSPZ Chemoprophylaxis Vaccine (PfSPZ-CVac), induces high-level protection against controlled huma
Externí odkaz:
https://doaj.org/article/c9858644c23843c88d0cea21da81dfcf
Autor:
Freisnel H. Mouzinga, Constanze Heinzel, Abel Lissom, Andrea Kreidenweiss, Armel L. Batchi‐Bouyou, Jacques D. Mbama Ntabi, Jean C. Djontu, Etienne Ngumbi, Peter G. Kremsner, Rolf Fendel, Francine Ntoumi
Publikováno v:
Immunity, Inflammation and Disease, Vol 11, Iss 12, Pp n/a-n/a (2023)
Abstract Background The efficacy of immunization against an airborne pathogen depends in part on its ability to induce antibodies at the major entry site of the virus, the mucosa. Recent studies have revealed that mucosal immunity is poorly activated
Externí odkaz:
https://doaj.org/article/75c2ceb95ac147daa5942a83bbbd756f
Autor:
Mohammed H. Cherkaoui‐Rbati, Nicole Andenmatten, Lydia Burgert, Oluwaseun F. Egbelowo, Rolf Fendel, Chiara Fornari, Michael Gabel, John Ward, Jörg J. Möhrle, Nathalie Gobeau
Publikováno v:
CPT: Pharmacometrics & Systems Pharmacology, Vol 12, Iss 1, Pp 50-61 (2023)
Abstract Chemoprophylactics are a vital tool in the fight against malaria. They can be used to protect populations at risk, such as children younger than the age of 5 in areas of seasonal malaria transmission or pregnant women. Currently approved che
Externí odkaz:
https://doaj.org/article/91245b38753741cfa2057e092803c40e
Autor:
Jule Rüter, Srinivas Reddy Pallerla, Christian G. Meyer, Nicolas Casadei, Michael Sonnabend, Silke Peter, Dennis Nurjadi, Le Thi Kieu Linh, Rolf Fendel, Siri Göpel, Olaf Riess, Peter G. Kremsner, Thirumalaisamy P. Velavan
Publikováno v:
International Journal of Infectious Diseases, Vol 122, Iss , Pp 427-436 (2022)
Objectives: Host genetic factors contribute to the variable severity of COVID-19. We examined genetic variants from genome-wide association studies and candidate gene association studies in a cohort of patients with COVID-19 and investigated the role
Externí odkaz:
https://doaj.org/article/acba52db8c344a23bceab088813d6163
Autor:
Mikhael D. Manurung, Sanne E. de Jong, Yvonne Kruize, Yoanne D. Mouwenda, Madeleine Eunice Betouke Ongwe, Yabo Josiane Honkpehedji, Jeannot Frézus Zinsou, Jean Claude Dejon-Agobe, Stephen L. Hoffman, Peter G. Kremsner, Ayola Akim Adegnika, Rolf Fendel, Benjamin Mordmüller, Meta Roestenberg, Bertrand Lell, Maria Yazdanbakhsh
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Controlled human malaria infection (CHMI) using cryopreserved non-attenuated Plasmodium falciparum sporozoites (PfSPZ) offers a unique opportunity to investigate naturally acquired immunity (NAI). By analyzing blood samples from 5 malaria-na
Externí odkaz:
https://doaj.org/article/c27d927e1b5843dab870f4f32ed86aa9
Autor:
Benjamin Mordmüller, Zita Sulyok, Mihály Sulyok, Zsofia Molnar, Albert Lalremruata, Carlos Lamsfus Calle, Patricia Granados Bayon, Meral Esen, Markus Gmeiner, Jana Held, Henri-Lynn Heimann, Tamirat Gebru Woldearegai, Javier Ibáñez, Judith Flügge, Rolf Fendel, Andrea Kreidenweiss, Natasha KC, Tooba Murshedkar, Sumana Chakravarty, Pouria Riyahi, Peter F. Billingsley, L. W. Preston Church, Thomas L. Richie, B. Kim Lee Sim, Stephen L. Hoffman, Peter G. Kremsner
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Immunization with radiation-attenuated Plasmodium falciparum (Pf) sporozoites (SPZ) in PfSPZ Vaccine, has provided better vaccine efficacy (VE) against controlled human malaria infection (CHMI) with the same parasites as in the vaccine (homo
Externí odkaz:
https://doaj.org/article/14917a5ef92d4531811eec64c343ca82
Autor:
Odilon Nouatin, Javier Ibáñez, Rolf Fendel, Ulysse A. Ngoa, Freia-Raphaella Lorenz, Jean-Claude Dejon-Agobé, Jean Ronald Edoa, Judith Flügge, Sina Brückner, Meral Esen, Michael Theisen, Stephen L. Hoffman, Kabirou Moutairou, Adrian J. F. Luty, Bertrand Lell, Peter G. Kremsner, Ayola A. Adegnika, Benjamin Mordmüller
Publikováno v:
Malaria Journal, Vol 21, Iss 1, Pp 1-16 (2022)
Abstract Background Antibody and cellular memory responses following vaccination are important measures of immunogenicity. These immune markers were quantified in the framework of a vaccine trial investigating the malaria vaccine candidate GMZ2. Meth
Externí odkaz:
https://doaj.org/article/978d148c1f4c454e841b756ef9fb6d02
Autor:
Javier Ibanez, Rolf Fendel, Freia-Raphaella Lorenz, Patricia Granados-Bayon, Sina Brückner, Meral Esen, Mihály Sulyok, Zita Sulyok, Steffen Borrmann, Petra Bacher, Alexander Scheffold, Stephen L. Hoffman, Peter G. Kremsner, Benjamin Mordmüller
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-11 (2022)
Abstract Repeated direct venous inoculation of Plasmodium falciparum sporozoites (PfSPZ) together with antimalarial chemoprophylaxis (PfSPZ–CVac) is the most potent way to induce sterile immunity against P. falciparum infection in malaria-naive vol
Externí odkaz:
https://doaj.org/article/557ad6c72b20435e92085c01ea4d8799