Zobrazeno 1 - 10
of 204
pro vyhledávání: '"Rolf E Brenner"'
Autor:
Jana Riegger, Rolf E Brenner
Publikováno v:
eLife, Vol 12 (2023)
Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilagehomeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis(OA). However, the underlying mechanisms of phenotypical alteratio
Externí odkaz:
https://doaj.org/article/0a01d1ef837042f5a3d0fce7af5d945b
Autor:
Lena Huber, David Gvaramia, Johann Kern, Yvonne Jakob, Frank G Zoellner, Daniela Hirsch, Roman Breiter, Rolf E Brenner, Nicole Rotter
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Nasal septum defects can currently only be reconstructed using autologous cartilage grafts. In this study, we examine the reconstruction of septal cartilage defects in a rabbit model using porcine decellularized nasal septal cartilage (DNSC) function
Externí odkaz:
https://doaj.org/article/4a8fc47ffff9419b87b1c18355b5d13a
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0116772 (2015)
Multipotent mesenchymal stromal cells (MSC) exert immune-modulatory effects and support tissue regeneration in various local trauma models. In case of a polytrauma, high amounts of danger-associated molecular patterns are released, leading to a syste
Externí odkaz:
https://doaj.org/article/1b135acd4a2c4f94aff2317a863d5496
Autor:
Annika Kasten, Tamara Naser, Kristina Brüllhoff, Jörg Fiedler, Petra Müller, Martin Möller, Joachim Rychly, Jürgen Groll, Rolf E Brenner
Publikováno v:
PLoS ONE, Vol 9, Iss 10, p e109411 (2014)
Designing of implant surfaces using a suitable ligand for cell adhesion to stimulate specific biological responses of stem cells will boost the application of regenerative implants. For example, materials that facilitate rapid and guided migration of
Externí odkaz:
https://doaj.org/article/111d8ed648ab4e55ae7f8a5cdfd6446a
Autor:
Julia V Wölfle, Jörg Fiedler, Lutz Dürselen, Judith Reichert, Dieter Scharnweber, Anne Förster, Bernd Schwenzer, Heiko Reichel, Anita Ignatius, Rolf E Brenner
Publikováno v:
PLoS ONE, Vol 9, Iss 1, p e86151 (2014)
The aim of the present study was to test the biocompatibility and functionality of orthopaedic bone implants with immobilized oligonucleotides serving as anchor stands for rhBMP-2 and rhVEGF-A conjugated with complementary oligonucleotides in an oste
Externí odkaz:
https://doaj.org/article/78cbdc2a471146c6aa2380e214105f73
Autor:
Amelie Kuhn, Markus Huber-Lang, Sebastian Weckbach, Jana Riegger, Graciosa Q. Teixeira, Volker Rasche, Jörg Fiedler, Cornelia Neidlinger-Wilke, Rolf E. Brenner
Publikováno v:
Biomedicines, Vol 12, Iss 8, p 1692 (2024)
Previous studies indicate an implication of the terminal complement complex (TCC) in disc degeneration (DD). To investigate the functional role of TCC in trauma-induced DD in vivo, the model of endplate (EP) drilling was first applied in rabbits usin
Externí odkaz:
https://doaj.org/article/d75f8a054d524407b6710a36f5300518
Autor:
Daniel Tews, Rolf E. Brenner, Reiner Siebert, Klaus-Michael Debatin, Pamela Fischer-Posovszky, Martin Wabitsch
Publikováno v:
International Journal of Obesity. 46:1939-1947
20 years ago, we described a human cell strain derived from subcutaneous adipose tissue of an infant supposed to have Simpson-Golabi-Behmel Syndrome (SGBS), thus called “SGBS cells”. Since then, these cells have emerged as the most commonly used
Autor:
Jana Riegger, Rolf E. Brenner
Accumulation of dysfunctional chondrocytes has detrimental consequences on the cartilage homeostasis and is thus thought to play a crucial role during the pathogenesis of osteoarthritis (OA). However, the underlying mechanisms of phenotypical alterat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::022a4e86189723f2752388c12bd40461
https://doi.org/10.1101/2023.05.08.539821
https://doi.org/10.1101/2023.05.08.539821
Autor:
Amelie Kuhn, Jana Riegger, Graciosa Q. Teixeira, Markus Huber-Lang, John D. Lambris, Cornelia Neidlinger-Wilke, Rolf E. Brenner
Publikováno v:
Cells; Volume 12; Issue 6; Pages: 887
Terminal complement complex (TCC) deposition was identified in human degenerated discs. To clarify the role of terminal complement activation in disc degeneration (DD), we investigated respective activating mechanisms and cellular effects in annulus
Autor:
Jana Riegger, Helga Joos, Valentin Möhler, Frank Leucht, Katrin Rading, Christian Kubisch, Anita Ignatius, Markus Huber-Lang, Rolf E. Brenner
Publikováno v:
Biomolecules
Volume 13
Issue 2
Pages: 216
Volume 13
Issue 2
Pages: 216
The terminal complement complex (TCC) has been described as a potential driver in the pathogenesis of posttraumatic osteoarthritis (PTOA). However, sublytic TCC deposition might also play a crucial role in bone development and regeneration. Therefore