Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Rolf Dargel"'
Autor:
Dietmar Plonné, Hans-Peter Schulze, Ulla Kahlert, Kerstin Meltke, Holger Seidolt, Andrew J. Bennett, Ian J. Cartwright, Joan A. Higgins, Uwe Till, Rolf Dargel
Publikováno v:
Journal of Lipid Research, Vol 42, Iss 11, Pp 1865-1878 (2001)
In this study, we explored the paradox that in suckling rats the serum concentration of LDL is high although the liver secretes only minimal quantities of VLDL, the presumed precursor of LDL. Freshly isolated hepatocytes and hepatocytes in primary cu
Externí odkaz:
https://doaj.org/article/139758f8efab4a4fb2b79859c8cf2af0
Publikováno v:
Liver. 10:94-105
— During human and experimental liver fibrogenesis, the pattern of glycosaminoglycans in fibrotic liver matrix is greatly changed by severalfold increases of hyaluronic acid, chondroitin sulfate, and dermatan sulfate, respectively. The present stud
Publikováno v:
Experimental and Toxicologic Pathology. 50:315-322
The aim of this study was to follow semiquantitatively by immunohistochemical means the alterations of the expression of the hepatic glycoproteins tenascin, fibronectin, and laminin in two different models of chronic liver injury, i.e. thioacetamide-
Publikováno v:
Journal of Hepatology. 28:461-470
Background/Aims: Reactive oxygen species play an essential role in necro-inflammatory processes. Therefore, the aim of the present studies was to investigate the effect of exogenous and endogenously produced H 2 O 2 on the phagocytic capacity and glu
Publikováno v:
Experimental and Toxicologic Pathology. 49:281-288
The aim of the present investigation was to assess in a correlated biochemical and morphological study the dynamics of fibrogenesis after bile duct ligation and to compare the time course of alterations with those occurring in thioacetamide induced l
Publikováno v:
Journal of Hepatology. 26:1093-1103
Background/Aims: Liver macrophages play an essential role in necro-inflammatory liver damage which leads to fibrosis and cirrhosis. The aim of the present study was to compare the mediator release and the DNA synthesis of macrophages at an early and
Publikováno v:
FEBS Letters. 391:57-60
The increase of hepatic apolipoprotein B (apoB) mRNA editing during rat development was not affected by hypothyroidism. Furthermore, the addition of 3,3′,5-triiodothyronine (T3) to cultured hepatocytes taken from fetal, neonatal and adult rats had
Autor:
Wolfgang Klinger, Michael Rost, Horst Rein, Rolf Dargel, E. Karge, Christine Reinemann, M. Kretzschmar, Hans-Peter Schulze
Publikováno v:
Experimental and Toxicologic Pathology. 48:447-460
For the investigation of luminol (LM)-and lucigenin (LC)-amplified chemiluminescence (CL) in rat liver microsomes using both a liquid-scintillation counter (LKB/Wallac 1219 Rackbeta) and a Berthold luminometer (AutoLumat LB 953) optimal incubation mi
Publikováno v:
Journal of Hepatology. 24:468-477
Background/Aims: The aim of the study presented here was to evaluate the basal and stimulated phagocytic activities and the metabolite production of isolated perfused livers, and also the phagocytic capacity of cultured Kupffer cells from rats with m
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1299:54-66
Explants of visceral rat yolk sacs from gestational days 16, 18 and 22 were used for studying developmental changes of secretion and density distribution of lipoproteins, particularly of those containing apoB. Moreover, the influence of fatty acid su