Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Rolf Boot"'
Autor:
Or Cabasso, Aparna Kuppuramalingam, Lindsey Lelieveld, Martijn Van der Lienden, Rolf Boot, Johannes M. Aerts, Mia Horowitz
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 22, p 16035 (2023)
In Gaucher disease (GD), a relatively common sphingolipidosis, the mutant lysosomal enzyme acid β-glucocerebrosidase (GCase), encoded by the GBA1 gene, fails to properly hydrolyze the sphingolipid glucosylceramide (GlcCer) in lysosomes, particularly
Externí odkaz:
https://doaj.org/article/a40a9c1486d74af0b5d3a6715e7fdbcb
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 1, p 66 (2018)
Several diseases are caused by inherited defects in lysosomes, the so-called lysosomal storage disorders (LSDs). In some of these LSDs, tissue macrophages transform into prominent storage cells, as is the case in Gaucher disease. Here, macrophages be
Externí odkaz:
https://doaj.org/article/295757102a1941749e1906f208dfbdbe
Autor:
Kah-Yee Li, Wouter Kallemeijn, Jianbing Jiang, Marthe Walvoort, Lianne Willems, Thomas Beenakker, Hans van den Elst, Gijs van der Marel, Jeroen Codée, Hans Aerts, Bogdan Florea, Rolf Boot, Martin Witte, Herman Overkleeft
Publikováno v:
Concepts and Case Studies in Chemical Biology
Concepts and Case Studies in Chemical Biology, 9783527336111, 191-206
Concepts and Case Studies in Chemical Biology, 9783527336111, 191-206
Activity-based probes (ABPs) have been developed for numerous serine hydrolases, cysteine proteases, and threonine hydrolases, but less frequently for other enzyme families. This chapter details the successful development and application of a number
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b305bb468de782c2b1c86dd49b881d1
https://doi.org/10.1002/9783527687503.ch13
https://doi.org/10.1002/9783527687503.ch13
Publikováno v:
Philosophical Transactions of the Royal Society B: Biological Sciences; May2003, Vol. 358 Issue 1433, p905-914, 10p
Conference
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.