Zobrazeno 1 - 10
of 462
pro vyhledávání: '"Rolf, Larsson"'
Autor:
Tove Selvin, Malin Berglund, Anders Åkerström, Marco Zia, Jakob Rudfeldt, Malin Jarvius, Rolf Larsson, Claes R Andersson, Mårten Fryknäs
Publikováno v:
SLAS Technology, Vol 29, Iss 6, Pp 100232- (2024)
To facilitate the translation of immunotherapies from bench to bedside, predictive preclinical models are essential. We developed the in vivo immuno-oncology Hollow Fiber Assay (HFA) to bridge the gap between simpler cell-based in vitro assays and mo
Externí odkaz:
https://doaj.org/article/d2e6640e28ad4e36aa4dfe94b2089f19
Autor:
Gebrenegus Ghilagaber, Rolf Larsson
Publikováno v:
Stats, Vol 6, Iss 4, Pp 1179-1197 (2023)
We address an inference issue where the value of a covariate is measured at the date of the survey but is used to explain behavior that has occurred long before the survey. This causes bias because the value of the covariate does not follow the tempo
Externí odkaz:
https://doaj.org/article/828845f44bdf404b895ac0de1baf22a9
Autor:
Tove Selvin, Malin Berglund, Lena Lenhammar, Malin Jarvius, Peter Nygren, Mårten Fryknäs, Rolf Larsson, Claes R Andersson
Publikováno v:
BMC Cancer, Vol 23, Iss 1, Pp 1-10 (2023)
Abstract Background High-throughput screening (HTS) of small molecule drug libraries has greatly facilitated the discovery of new cancer drugs. However, most phenotypic screening platforms used in the field of oncology are based solely on cancer cell
Externí odkaz:
https://doaj.org/article/6a001318eb47461bbdbb33b4e9a1a25b
Autor:
Rolf Larsson, Antti Belinskij, Bjørn Kløve, Diana Meilutyte-Lukauskiene, Elve Lode, Eva Skarbøvik, Vytautas Akstinas
Publikováno v:
Hydrology Research, Vol 53, Iss 9, Pp 1166-1185 (2022)
The European Union (EU) Water Framework Directive is of paramount importance for water management. According to the legal text, coordination with other directives like the Floods Directive is imperative and motivated by potential synergy effects. In
Externí odkaz:
https://doaj.org/article/bcfe0949886c4bf5b28f0f4566ddfbca
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Understanding the immunological effects of chemotherapy is of great importance, especially now that we have entered an era where ever-increasing pre-clinical and clinical efforts are put into combining chemotherapy and immunotherapy to comba
Externí odkaz:
https://doaj.org/article/6dcaee7294064a91aaf98e56ddd64e38
Autor:
Frida Ek, Kristin Blom, Tove Selvin, Jakob Rudfeldt, Claes Andersson, Wojciech Senkowski, Christian Brechot, Peter Nygren, Rolf Larsson, Malin Jarvius, Mårten Fryknäs
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Quiescent cancer cells in malignant tumors can withstand cell-cycle active treatment and cause cancer spread and recurrence. Three-dimensional (3D) cancer cell models have led to the identification of oxidative phosphorylation (OXPHOS) as a
Externí odkaz:
https://doaj.org/article/cec5dfaf28ed4348a1f75ca8afb092cf
Autor:
Xi Lu, Naga Prathyusha Maturi, Malin Jarvius, Irem Yildirim, Yonglong Dang, Linxuan Zhao, Yuan Xie, E-Jean Tan, Pengwei Xing, Rolf Larsson, Mårten Fryknäs, Lene Uhrbom, Xingqi Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The epigenetic regulation of glioblastoma stem cell (GSC) function remains poorly understood. Here, the authors compare the chromatin accessibility landscape of GSC cultures from mice and patients and suggest that the epigenome of GSCs is cell lineag
Externí odkaz:
https://doaj.org/article/54f5b29285c34347a7324d03fb75af42
Autor:
Julia Steinmetz, Wojciech Senkowski, Johan Lengqvist, Jenny Rubin, Elena Ossipova, Stephanie Herman, Rolf Larsson, Per-Johan Jakobsson, Mårten Fryknäs, Kim Kultima
Publikováno v:
ACS Omega, Vol 5, Iss 28, Pp 17242-17254 (2020)
Externí odkaz:
https://doaj.org/article/2948cc8342e74ebebaf02b979d03e116
Autor:
Konstantin Byrgazov, Thomas Lind, Annica J. Rasmusson, Claes Andersson, Ana Slipicevic, Fredrik Lehmann, Joachim Gullbo, Håkan Melhus, Rolf Larsson, Mårten Fryknäs
Publikováno v:
Bone Reports, Vol 15, Iss , Pp 101098- (2021)
Myeloma bone disease is a major complication in multiple myeloma affecting quality of life and survival. It is characterized by increased activity of osteoclasts, bone resorbing cells. Myeloma microenvironment promotes excessive osteoclastogenesis, a
Externí odkaz:
https://doaj.org/article/cd014e14ebe249af86995086ee1a9c0e
Autor:
Kristin Blom, Jenny Rubin, Malin Berglund, Malin Jarvius, Lena Lenhammar, Vendela Parrow, Claes Andersson, Angelica Loskog, Mårten Fryknäs, Peter Nygren, Rolf Larsson
Publikováno v:
BMC Research Notes, Vol 12, Iss 1, Pp 1-7 (2019)
Abstract Objective We recently showed that the anti-helminthic compound mebendazole (MBZ) has immunomodulating activity by inducing a M2 to M1 phenotype switch in monocyte/macrophage models. In the present study we investigated the potential role of
Externí odkaz:
https://doaj.org/article/0315674a9bed4c85a44bce844792df11