Zobrazeno 1 - 10
of 211
pro vyhledávání: '"Rolf, Breinbauer"'
Autor:
Lisa Kofler, Lorenz Grundmann, Magdalena Gerhalter, Michael Prattes, Juliane Merl-Pham, Gertrude Zisser, Irina Grishkovskaya, Victor-Valentin Hodirnau, Martin Vareka, Rolf Breinbauer, Stefanie M. Hauck, David Haselbach, Helmut Bergler
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract The formation of new ribosomes is tightly coordinated with cell growth and proliferation. In eukaryotes, the correct assembly of all ribosomal proteins and RNAs follows an intricate scheme of maturation and rearrangement steps across three c
Externí odkaz:
https://doaj.org/article/fe79ff94017b46469f0c1f775d2e6f81
Publikováno v:
Communications Chemistry, Vol 7, Iss 1, Pp 1-12 (2024)
Abstract Glycosylated derivatives of natural product polyphenols display a spectrum of biological activities, rendering them critical for both nutritional and pharmacological applications. Their enzymatic synthesis by glycosyltransferases is frequent
Externí odkaz:
https://doaj.org/article/8757e95a5aa04497b6a99324b924d712
Autor:
Lisa Pöltl, Maksym Kitsera, Sandra Raffl, Stefan Schild, Amar Cosic, Sabine Kienesberger, Katrin Unterhauser, Georg Raber, Christian Lembacher-Fadum, Rolf Breinbauer, Gregor Gorkiewicz, Carlos Sebastian, Gerald Hoefler, Ellen L. Zechner
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112199- (2023)
Summary: The DNA-alkylating metabolite tilimycin is a microbial genotoxin. Intestinal accumulation of tilimycin in individuals carrying til+ Klebsiella spp. causes apoptotic erosion of the epithelium and colitis. Renewal of the intestinal lining and
Externí odkaz:
https://doaj.org/article/be2aa7e0300d443782126a41699edb73
Autor:
Elien Grajchen, Melanie Loix, Paulien Baeten, Beatriz F. Côrte-Real, Ibrahim Hamad, Sam Vanherle, Mansour Haidar, Jonas Dehairs, Jelle Y. Broos, James M. Ntambi, Robert Zimmermann, Rolf Breinbauer, Piet Stinissen, Niels Hellings, Sanne G. S. Verberk, Gijs Kooij, Martin Giera, Johannes V. Swinnen, Bieke Broux, Markus Kleinewietfeld, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Publikováno v:
Cellular and Molecular Immunology, 20(6), 666-679. Nature Publishing Group
Grajchen, E, Loix, M, Baeten, P, Côrte-Real, B F, Hamad, I, Vanherle, S, Haidar, M, Dehairs, J, Broos, J Y, Ntambi, J M, Zimmermann, R, Breinbauer, R, Stinissen, P, Hellings, N, Verberk, S G S, Kooij, G, Giera, M, Swinnen, J V, Broux, B, Kleinewietfeld, M, Hendriks, J J A & Bogie, J F J 2023, ' Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity ', Cellular and Molecular Immunology, vol. 20, no. 6, pp. 666-679 . https://doi.org/10.1038/s41423-023-01011-2
Grajchen, E, Loix, M, Baeten, P, Côrte-Real, B F, Hamad, I, Vanherle, S, Haidar, M, Dehairs, J, Broos, J Y, Ntambi, J M, Zimmermann, R, Breinbauer, R, Stinissen, P, Hellings, N, Verberk, S G S, Kooij, G, Giera, M, Swinnen, J V, Broux, B, Kleinewietfeld, M, Hendriks, J J A & Bogie, J F J 2023, ' Fatty acid desaturation by stearoyl-CoA desaturase-1 controls regulatory T cell differentiation and autoimmunity ', Cellular and Molecular Immunology, vol. 20, no. 6, pp. 666-679 . https://doi.org/10.1038/s41423-023-01011-2
The imbalance between pathogenic and protective T cell subsets is a cardinal feature of autoimmune disorders such as multiple sclerosis (MS). Emerging evidence indicates that endogenous and dietary-induced changes in fatty acid metabolism have a majo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0453077196c63a160f7fb022361b2740
https://cris.maastrichtuniversity.nl/en/publications/91c2f0c1-489d-4001-92ff-b59bf00eacea
https://cris.maastrichtuniversity.nl/en/publications/91c2f0c1-489d-4001-92ff-b59bf00eacea
Autor:
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 1020-1031 (2019)
Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and
Externí odkaz:
https://doaj.org/article/6811fbb03319497cbbdc699b457cff47
Autor:
Martin Breugst, Jennifer N. Andexer, Sebastian B. Beil, Rolf Breinbauer, Oliver Dumele, Martin Ernst, Urs Gellrich, Philipp Germer, Michael Giese, Tobias A. M. Gulder, Peter Huy, Wolfgang Hüttel, Stephanie Kath‐Schorr, Karsten Körber, Markus Kordes, Christian Kuttruff, Thomas Lindel, Robin Meier, Sebastian Myllek, Norbert Schaschke, Fabian Pfrengle, Jörg Pietruszka, Hanna Sebode, Mathias O. Senge, Golo Storch, Bernd F. Straub, Johannes Teichert, Siegfried R. Waldvogel, Thomas Werner, Christian Winter
Publikováno v:
Nachrichten aus der Chemie. 71:40-66
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c22ebb359da73247b549ae13fd09f339
https://doi.org/10.1002/nadc.20234135542
https://doi.org/10.1002/nadc.20234135542
Autor:
Christoph Grininger, Mario Leypold, Philipp Aschauer, Tea Pavkov-Keller, Lina Riegler-Berket, Rolf Breinbauer, Monika Oberer
Publikováno v:
Biomolecules, Vol 11, Iss 9, p 1299 (2021)
Tuberculosis continues to be a major threat to the human population. Global efforts to eradicate the disease are ongoing but are hampered by the increasing occurrence of multidrug-resistant strains of Mycobacterium tuberculosis. Therefore, the develo
Externí odkaz:
https://doaj.org/article/eeaaa409491e4e64a129545cc656268b
Autor:
Christina Diederich, Mario Leypold, Martin Culka, Hansjörg Weber, Rolf Breinbauer, G. Matthias Ullmann, Wulf Blankenfeldt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Abstract Phenazines are bacterial virulence and survival factors with important roles in infectious disease. PhzF catalyzes a key reaction in their biosynthesis by isomerizing (2 S,3 S)-2,3-dihydro-3-hydroxy anthranilate (DHHA) in two steps, a [1,5]-
Externí odkaz:
https://doaj.org/article/2067ab1830ad4e8891977558d2293393
Autor:
Martina Schweiger, Matthias Romauch, Renate Schreiber, Gernot F. Grabner, Sabrina Hütter, Petra Kotzbeck, Pia Benedikt, Thomas O. Eichmann, Sohsuke Yamada, Oskar Knittelfelder, Clemens Diwoky, Carina Doler, Nicole Mayer, Werner De Cecco, Rolf Breinbauer, Robert Zimmermann, Rudolf Zechner
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-15 (2017)
The enzyme Atgl participates in the breakdown of lipids in adipose tissue. Here the authors show that pharmacological inhibition of Atgl reduces weight gain and improves metabolic health in mice fed a high-fat diet, without causing adverse effects in
Externí odkaz:
https://doaj.org/article/6897b936ca4b4463ba1c491fe09495d6
Autor:
Julia Kriegesmann, Thomas Schlatzer, Kateryna Che, Claudia Altdorf, Susanne Huhmann, Hanspeter Kählig, Dennis Kurzbach, Rolf Breinbauer, Christian F. W. Becker
Publikováno v:
ChemBioChem.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf73d7c12e67ec7ed56e6a8765ff498
https://doi.org/10.1002/cbic.202300098
https://doi.org/10.1002/cbic.202300098