Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Roleen Sharma"'
Autor:
Paul T. King, Lovisa Dousha, Nadeene Clarke, Jennifer Schaefer, Rosemary Carzino, Roleen Sharma, Ken L. Wan, Aveena Anantharajah, Kim O'Sullivan, Zhong X. Lu, Stephen R. Holdsworth, Sarath Ranganathan, Philip G. Bardin, David S. Armstrong
Publikováno v:
ERJ Open Research, Vol 7, Iss 2 (2021)
Childhood lung infection is often associated with prominent neutrophilic airway inflammation and excess production of proteases such as neutrophil elastase (NE). The mechanisms responsible for this inflammation are not well understood. One potentiall
Externí odkaz:
https://doaj.org/article/117403dc98d74041be104999276d522c
Autor:
Paul T. King, Roleen Sharma
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Haemophilus influenzae is divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (d
Externí odkaz:
https://doaj.org/article/f1b3271e0a0a48a1a163ac792a357521
Autor:
Paul T King, Roleen Sharma, Kim O'Sullivan, Stavros Selemidis, Steven Lim, Naghmeh Radhakrishna, Camden Lo, Jyotika Prasad, Judy Callaghan, Peter McLaughlin, Michael Farmer, Daniel Steinfort, Barton Jennings, James Ngui, Bradley R S Broughton, Belinda Thomas, Ama-Tawiah Essilfie, Michael Hickey, Peter W Holmes, Philip Hansbro, Philip G Bardin, Stephen R Holdsworth
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120371 (2015)
Nontypeable Haemophilus influenzae (NTHi) is a prevalent bacterium found in a variety of chronic respiratory diseases. The role of this bacterium in the pathogenesis of lung inflammation is not well defined. In this study we examined the effect of NT
Externí odkaz:
https://doaj.org/article/2c10d59797b34610a811b91fc9d1f67b
Autor:
Stephen R. Holdsworth, Philip G. Bardin, Nadeene Clarke, Ken L. Wan, Zhong X. Lu, David S. Armstrong, Roleen Sharma, Jennifer Schaefer, Paul T. King, Rosemary Carzino, Sarath Ranganathan, Kim M. O’Sullivan, Aveena Anantharajah, Lovisa Dousha
Publikováno v:
ERJ Open Research
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 2 (2021)
article-version (VoR) Version of Record
ERJ Open Research, Vol 7, Iss 2 (2021)
Childhood lung infection is often associated with prominent neutrophilic airway inflammation and excess production of proteases such as neutrophil elastase (NE). The mechanisms responsible for this inflammation are not well understood. One potentiall
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9f6ecb8c761539ff51c3635e0961ad7
https://doi.org/10.1183/23120541.00883-2020
https://doi.org/10.1183/23120541.00883-2020
Publikováno v:
Journal of visualized experiments : JoVE. (172)
Haemophilus influenzae (Hi) is a prevalent bacterium found in a range of respiratory conditions. A variety of different assays/techniques may be used to assess the respiratory immune/inflammatory response to this bacterium. Flow cytometry and confoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e2e5f929f2a658cf668b6bba1107e13
https://pubmed.ncbi.nlm.nih.gov/34279491
https://pubmed.ncbi.nlm.nih.gov/34279491
Publikováno v:
Journal of Visualized Experiments.
Haemophilus influenzae (Hi) is a prevalent bacterium found in a range of respiratory conditions. A variety of different assays/techniques may be used to assess the respiratory immune/inflammatory response to this bacterium. Flow cytometry and confoca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::944d04212baf0a9a6ec46a33049358cd
https://doi.org/10.3791/62572-v
https://doi.org/10.3791/62572-v
Publikováno v:
Journal of Visualized Experiments.
A primary method used to define the presence of neutrophil extracellular traps (NETs) is confocal microscopy. We have modified established confocal microscopy methods to visualize macrophage extracellular traps (METs). These extracellular traps are d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05231d5debfd634b40225529adf7af74
https://doi.org/10.3791/56459
https://doi.org/10.3791/56459
Autor:
Saleela Ruwanpura, Paul T. King, Kim M. O’Sullivan, Belinda J. Thomas, Lovisa Dousha, Judy M. Callaghan, Stavros Selemidis, Roleen Sharma, Gavin De Carle Brooks, Michael Farmer, Michaela Finsterbusch, Gary P. Anderson, Barton R Jennings, Steven Lim, Philip G. Bardin, Stephen R. Holdsworth
Publikováno v:
Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Our aim was to investigate if deoxyribonuclease (DNase) 1 is a potential therapeutic agent to reduce pathogenic effects of cigarette smoke exposure in the lung. Cigarette smoke causes protease imbalance with excess production of proteases, which is a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4853588de49460d7e8e01050b6da1d4f
https://doi.org/10.1038/s41598-017-12474-5
https://doi.org/10.1038/s41598-017-12474-5
Autor:
Roleen Sharma, Philip G. Bardin, Philip M. Hansbro, Kim M. O’Sullivan, Peter Holmes, Michael Farmer, Stavros Selemidis, Steven Lim, James Ngui, Stephen R. Holdsworth, Michael J. Hickey, Jyotika D Prasad, Peter McLaughlin, Barton R Jennings, Paul T. King, Camden Lo, Ama-Tawiah Essilfie, Daniel P Steinfort, Judith Mary Callaghan, Naghmeh Radhakrishna, Belinda J. Thomas, Bradley Randal Scott Broughton
Publikováno v:
PLoS ONE, Vol 10, Iss 3, p e0120371 (2015)
PLoS ONE
PLoS ONE
© 2015 King et al. Nontypeable Haemophilus influenzae (NTHi) is a prevalent bacterium found in a variety of chronic respiratory diseases. The role of this bacterium in the pathogenesis of lung inflammation is not well defined. In this study we exami
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a5aaf4c08b80513bdf6fe2042d838da
http://europepmc.org/articles/PMC4368769?pdf=render
http://europepmc.org/articles/PMC4368769?pdf=render
Autor:
Roleen Sharma, Paul T. King
Publikováno v:
Journal of Immunology Research, Vol 2015 (2015)
Journal of Immunology Research
Journal of Immunology Research
Haemophilus influenzaeis divided into typeable or nontypeable strains based on the presence or absence of a polysaccharide capsule. The typeable strains (such as type b) are an important cause of systemic infection, whilst the nontypeable strains (de
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5bd2e037841d71e3741205773064b6f
https://doaj.org/article/f1b3271e0a0a48a1a163ac792a357521
https://doaj.org/article/f1b3271e0a0a48a1a163ac792a357521