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Amorphous nanoparticles by self-assembly: processing for controlled release of hydrophobic molecules
Autor:
Jie, Feng, Yingyue, Zhang, Simon A, McManus, Rolane, Qian, Kurt D, Ristroph, Hanu, Ramachandruni, Kai, Gong, Claire E, White, Aditya, Rawal, Robert K, Prud'homme
Publikováno v:
Soft matter. 15(11)
More than 40% of newly developed drug molecules are highly hydrophobic and, thus, suffer from low bioavailability. Kinetically trapping the drug as a nanoparticle in an amorphous state enhances solubility. However, enhanced solubility can be compromi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::643cf15b03e9dfe68f4d07d3d7128bb5
https://pubmed.ncbi.nlm.nih.gov/30776040
https://pubmed.ncbi.nlm.nih.gov/30776040
