Výsledky vyhledávání - "Rolando Paez"

Screening for stability and compatibility conditions of recombinant human epidermal growth factor for parenteral formulation: Effect of pH, buffers, and excipients

Autor: Jesús Noda, Yaima González, Héctor Santana, Rosangela Itri, Alejandro Beldarraín, Odalys Amarantes, Rolando Paez, Patricia T. Campana

Publikováno v: Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

A successful parenteral formulation can be developed by studying stability and compatibility of biopharmaceuticals as a function of solution composition. Here, we evaluate the influence of pH, buffers, ionic strength, protein concentration and presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6462f8ac945a2d0ccf7c0d5243d9d567
https://doi.org/10.1016/j.ijpharm.2013.04.054

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How does growth hormone releasing hexapeptide self-assemble in nanotubes?

Autor: Viviana Falcon, Leandro R.S. Barbosa, César Ávila, Rolando Paez, Nora Ventosa, Jaume Veciana, Rosangela Itri, Adalberto Pessoa, Héctor Santana, Ingrid Cabrera

Publikováno v: CONICET Digital (CONICET)
Consejo Nacional de Investigaciones Científicas y Técnicas
instacron:CONICET
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP

Growth hormone releasing peptide, GHRP-6, a hexapeptide (His-(D-Trp)-Ala-Trp-(D-Phe)-Lys-NH2, MW = 872.44 Da) that belongs to a class of synthetic growth hormone secretagogues, can stimulate growth hormone secretion from somatotrophs in several speci

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::639046fb2ab5bc1674f24a3f6ea6012e
http://pubs.rsc.org/en/Content/ArticleLanding/2014/SM/C4SM01693A#!divAbstract

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An integral approach towards a practical application for a plant-made monoclonal antibody in vaccine purification

Publikováno v: Vaccine. 23(15)

The use of transgenic plants for the production of pharmaceutical compounds has received increasing attention in the last few years. However, many technological and regulatory issues regarding the practical exploitation of this alternative system of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a459efba868be327cef729aa732b094
https://pubmed.ncbi.nlm.nih.gov/15734051

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Akademický článek

Interferon-lambda 3 and 4 Polymorphisms Increase Sustained Virological Responses and Regulate Innate Immunity in Antiviral Therapy With Pegylated Interferon-Alpha

Publikováno v: Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)

Sustained virologic response (SVR) in chronic hepatitis C (CHC) treatment denotes that the host genetics controls the immune response and unequivocally contribute to viral clearance or disease severity. In this context, single nucleotide polymorphism

Externí odkaz: https://doaj.org/article/7f83e57550ec48399e31a3e594db5543

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Expression and characterization of an anti-(hepatitis B surface antigen) glycosylated mouse antibody in transgenic tobacco (Nicotiana tabacum) plants and its use in the immunopurification of its target antigen

Autor: Marlene Pérez, Rodolfo Valdés, Guillermo Selman-Housein, Yasser Hevia, Nadia Ramírez, A. B. Martinez, Rolando Paez, M. Rodríguez, Marta Ayala, Marbelis Linares, Jorge V. Gavilondo, José A. Cremata

Publikováno v: Biotechnology and Applied Biochemistry. 38:223

Transgenic plants expressing recombinant immunoglobulins have arisen as an alternative technology for the large-scale production of antibodies useful in therapeutics and in industrial processes. In the present paper we report the expression in transg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6a2cc330dcc4929fac7ddcb834578b2
https://doi.org/10.1042/ba20030028

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Akademický článek

Pharmacokinetics comparison of two pegylated interferon alfa formulations in healthy volunteers

Autor: Marisa Boff Costa, Paulo Dornelles Picon, Guilherme Becker Sander, Hugo Nodarse Cuni, Carmen Valenzuela Silva, Rolando Páez Meireles, Ana Carolina Magalhães Andrade Góes, Nadia Maria Batoreu, Maria de Lourdes de Sousa Maia, Elizabeth Maciel Albuquerque, Denise Cristina de Souza Matos, Pedro Lopez Saura

Publikováno v: BMC Pharmacology and Toxicology, Vol 19, Iss 1, Pp 1-8 (2018)

Abstract Background Several countries have used pegylation technology to improve the pharmacokinetic properties of essential drugs. Recently, a novel interferon alfa-2b protein conjugated to four-branched 12 kDa polyethylene glycol molecules was deve

Externí odkaz: https://doaj.org/article/ada7798ae8e14c05b74b5ec1fb74647d

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Akademický článek

Increased bioavailability of IFN α 2b modified by chemical conjugation to a two-branched polyethyleneglycol molecule

Publikováno v: Biotecnología Aplicada, Vol 32, Iss 3, Pp 3521-3523 (2015)

Externí odkaz: https://doaj.org/article/cf6467f285794d27a05747f98bc47aeb

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Akademický článek

Acalasia, experiencia de 6 años. Hospital 'Dr. Rafael Ángel Calderón Guardia' (2001-2007)

Autor: Viviana Hernández-de Mezerville, Edgar Izquierdo-Sandí, Gerardo Avendaño-Alvarado, Ricardo Barahona-García, Alessia Ávalos-Giugliarelli, Rolando Páez-Sáenz, Rigoberto Salas-Aguilar

Publikováno v: Acta Médica Costarricense, Vol 51, Iss 2, Pp 98-102 (2009)

Objetivos: Caracterizar la población de pacientes vistos con esta entidad en el Hospital "Dr. Rafael Angel Calderón Guardia" durante los últimos 6 años y determinar su presentación clínica, método(s) de diagnóstico utilizado (s), tratamiento

Externí odkaz: https://doaj.org/article/aa3b4994ae8e48059262744087b9c1b1

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