Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Rolando E Yanes"'
Autor:
Tereza Moore, Rolando E Yanes, Melissa A Calton, Douglas Vollrath, Gregory M Enns, Tina M Cowan
Publikováno v:
PLoS ONE, Vol 15, Iss 10, p e0240517 (2020)
Mitochondrial diseases are a clinically heterogenous group of disorders caused by respiratory chain dysfunction and associated with progressive, multi-systemic phenotype. There is no effective treatment or cure, and no FDA-approved drug for treating
Externí odkaz:
https://doaj.org/article/743c8b3b1cd748f48faba2d1f592c372
Publikováno v:
Seminars in Hematology. 54:33-38
Immune aging is a multi-faceted process that manifests as reduced competence to fight infections and malignant cells, as well as diminished tissue repair, unprovoked inflammation, and increased autoreactivity. The aging adaptive immune system, with i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239c4e89407ae6123f783a261eaba64a
https://doi.org/10.1053/j.seminhematol.2016.10.003
https://doi.org/10.1053/j.seminhematol.2016.10.003
Autor:
Themistocles L. Assimes, Cornelia M. Weyand, Rolando E. Yanes, Markus Zeisbrich, Jörg J. Goronzy, Jison Hong, Lukas Brosig, Ryu Watanabe, John C. Giacomini, Yinyin Li, Hui Zhang, Barbara B. Wallis
ObjectivesAccelerated atherosclerotic disease typically complicates rheumatoid arthritis (RA), leading to premature cardiovascular death. Inflammatory macrophages are key effector cells in both rheumatoid synovitis and the plaques of coronary artery
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab93a5796d8a5c74c3d2f8ee6b6a0b6
https://europepmc.org/articles/PMC6589337/
https://europepmc.org/articles/PMC6589337/
Autor:
David Moskowitz, William J. Greenleaf, Cornelia M. Weyand, Bin Hu, David W. Zhang, Zhongde Ye, Jason D. Buenrostro, Jörg J. Goronzy, Sabine Le Saux, Rolando E. Yanes
Publikováno v:
Science Immunology. 2
The efficacy of the adaptive immune response declines dramatically with age, but the cell-intrinsic mechanisms driving immune aging in humans remain poorly understood. Immune aging is characterized by a loss of self-renewing naïve cells and the accu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::03d5ccaba618ee1d269ab4efac830fab
https://doi.org/10.1126/sciimmunol.aag0192
https://doi.org/10.1126/sciimmunol.aag0192
Autor:
Courtney R. Thomas, J. Fraser Stoddart, Daniel P. Ferris, Chris M. Gothard, Jeffrey I. Zink, Fuyuhiko Tamanoi, Jie Lu, Rolando E. Yanes, John Carl Olsen
Publikováno v:
Small. 7:1816-1826
Synthetic methodologies integrating hydrophobic drug delivery and biomolecular targeting with mesoporous silica nanoparticles are described. Transferrin and cyclic-RGD peptides are covalently attached to the nanoparticles utilizing different techniqu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7110040fb836cf850d65d00014d7e89
https://doi.org/10.1002/smll.201002300
https://doi.org/10.1002/smll.201002300
Autor:
Rolando E Yanes, Jorg J Goronzy
Publikováno v:
The Journal of Immunology. 196:204.4-204.4
Upon activation, T cells enter a developmental program characterized by clonal expansion and effector cell differentiation followed by contraction and survival of long-lived memory T cells. This program is regulated by interplay of activation-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::397ff06233e56d4fb5f1d57ba95eab30
https://doi.org/10.4049/jimmunol.196.supp.204.4
https://doi.org/10.4049/jimmunol.196.supp.204.4
The glycolytic enzyme PKM2 bridges metabolic and inflammatory dysfunction in coronary artery disease
Autor:
Tsuyoshi Shirai, Rafal R. Nazarewicz, Barbara B. Wallis, Rolando E. Yanes, Ryu Watanabe, Marc Hilhorst, Lu Tian, David G. Harrison, John C. Giacomini, Themistocles L. Assimes, Jörg J. Goronzy, Cornelia M. Weyand
Publikováno v:
The Journal of Cell Biology
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f9b7c3f7782fff8d15a4467b3abcdac
https://doi.org/10.1083/jcb.2126oia43
https://doi.org/10.1083/jcb.2126oia43
Autor:
Angela A. Hwang, Courtney R. Thomas, Jie Lu, Jeffrey I. Zink, April D. Pyle, Daniel P. Ferris, Sean P. Sherman, Fuyuhiko Tamanoi, Derrick Tarn, Rolando E. Yanes
Publikováno v:
Small (Weinheim an der Bergstrasse, Germany). 9(5)
Advances in nanotechnology have resulted in the development of new nanoparticles that have the potential to revolutionize medicine. Many nanomaterials have been engineered that promise to enhance drug delivery efficacy to target tissues, reduce side
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64fa2fa52258143a66132fe77596018
https://pubmed.ncbi.nlm.nih.gov/23152124
https://pubmed.ncbi.nlm.nih.gov/23152124
Autor:
Fuyuhiko Tamanoi, Rolando E. Yanes
Publikováno v:
Therapeutic delivery. 3(3)
The development of delivery vehicles that would carry therapeutic agents selectively to cancer cells has become an important focus in biomedical research. Nanoparticles have received much attention because the advances made in this field have resulte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3566de4e82cf73d4487f30ba40611e8
https://pubmed.ncbi.nlm.nih.gov/22506096
https://pubmed.ncbi.nlm.nih.gov/22506096
Recent advance in the study of cancer genome has led to the realization that small interference RNAs (siRNAs) provide an attractive type of anticancer reagents that can inhibit the expression of genes that are upregulated or whose gene products are o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fd9917278ffa9dca539945c1059db0e
https://doi.org/10.1016/b978-0-12-404741-9.00009-x
https://doi.org/10.1016/b978-0-12-404741-9.00009-x