Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Rolando Berlinguer Palmini"'
Autor:
Pankaj Singla, Thomas Broughton, Mark V. Sullivan, Saweta Garg, Rolando Berlinguer‐Palmini, Priyanka Gupta, Katie J Smith, Ben Gardner, Francesco Canfarotta, Nicholas W. Turner, Eirini Velliou, Shoba Amarnath, Marloes Peeters
Publikováno v:
Advanced Science, Vol 11, Iss 36, Pp n/a-n/a (2024)
Abstract Efficient and site‐specific delivery of therapeutics drugs remains a critical challenge in cancer treatment. Traditional drug nanocarriers such as antibody‐drug conjugates are not generally accessible due to their high cost and can lead
Externí odkaz:
https://doaj.org/article/41c450292aa14f44b006620b744b2c09
Autor:
Na Dong, Emily Johnson, Rolando Berlinguer-Palmini, Hongze Zhong, Fahimeh Dehkhoda, Ahmed Soltan, Konstantin Nikolic, Nir Grossman, Johannes Gausden, Richard Bailey, Anthony O'Neill, Andrew Jackson, Andrew Trevelyan, Patrick Degenaar, Xiaohan Sun
Publikováno v:
IEEE Access, Vol 12, Pp 129160-129172 (2024)
Optogenetic-based neuroprosthetic therapies are increasingly being considered for human trials. However, the optoelectronic design of clinical-grade optogenetic-based neuroprosthetic probes still requires some thought. Design constraints include ligh
Externí odkaz:
https://doaj.org/article/ac91f84e144444fa93c3a856acdf0c11
Autor:
Annachiara Scalzone, Clara Sanjurjo-Rodríguez, Rolando Berlinguer-Palmini, Anne M. Dickinson, Elena Jones, Xiao-Nong Wang, Rachel E. Crossland
Publikováno v:
Bioengineering, Vol 11, Iss 4, p 388 (2024)
Osteoarthritis (OA) is a degenerative joint disease, causing impaired mobility. There are currently no effective therapies other than palliative treatment. Mesenchymal stromal cells (MSCs) and their secreted extracellular vesicles (MSC-EVs) have show
Externí odkaz:
https://doaj.org/article/3eba0926a7004ac5b7f560d2a41b1917
Autor:
Xuefei Yu, Catherine Arden, Rolando Berlinguer-Palmini, Chun Chen, Carla Bradshaw, Anna LM Smith, Julia Whitehall, Michael White, Scott Anderson, Nicole Kattner, James Shaw, Doug Turnbull, Laura C Greaves, Mark Walker
Publikováno v:
Molecular Metabolism, Vol 60, Iss , Pp 101489- (2022)
Objective: There is strong evidence that mitochondrial DNA mutations and mitochondrial dysfunction play a role in diabetes pathogenesis. The homozygous knock-in mtDNA mutator mouse is a model of premature aging due to the accumulation of mitochondria
Externí odkaz:
https://doaj.org/article/7ed661841b25429ebf527135df0d42bd
Autor:
Lisa Prendergast, Urszula L. McClurg, Rossitsa Hristova, Rolando Berlinguer-Palmini, Sarah Greener, Katie Veitch, Inmaculada Hernandez, Philippe Pasero, Daniel Rico, Jonathan M. G. Higgins, Anastas Gospodinov, Manolis Papamichos-Chronakis
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-18 (2020)
In mammalian cells, during transcription and replication, RNA:DNA hybrid structures known as R-loops can arise, posing as obstacles to replication fork progression. Here the authors reveal that the ATP-dependent chromatin remodelling INO80 complex pr
Externí odkaz:
https://doaj.org/article/dcd1345330a848728d9de1a0310ef7f0
Autor:
Elisa Landucci, Rolando Berlinguer-Palmini, Gilda Baccini, Francesca Boscia, Elisabetta Gerace, Guido Mannaioni, Domenico E. Pellegrini-Giampietro
Publikováno v:
Cells, Vol 11, Iss 19, p 3015 (2022)
In this study, we investigated the cross-talk between mGlu1 and CB1 receptors in modulating GABA hippocampal output in whole-cell voltage clamp recordings in rat hippocampal acute slices, in organotypic hippocampal slices exposed to oxygen and glucos
Externí odkaz:
https://doaj.org/article/e9adff1f19ec4cd3893bef3576d26761
Autor:
Bassier Zadran, Praveen Dhondurao Sudhindar, Daniel Wainwright, Yvonne Bury, Saimir Luli, Rachel Howarth, Misti Vanette McCain, Robyn Watson, Hannah Huet, Fanni Palinkas, Rolando Berlinguer-Palmini, John Casement, Derek A. Mann, Fiona Oakley, John Lunec, Helen Reeves, Geoffrey J. Faulkner, Ruchi Shukla
Publikováno v:
British Journal of Cancer. 128:1236-1248
Background Molecular characterisation of hepatocellular carcinoma (HCC) is central to the development of novel therapeutic strategies for the disease. We have previously demonstrated mutagenic consequences of Long-Interspersed Nuclear Element-1 (LINE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c90dab2a8ed53492f5015164c5a984f3
https://doi.org/10.1038/s41416-023-02154-9
https://doi.org/10.1038/s41416-023-02154-9
Autor:
Christin A. Albus, Rolando Berlinguer-Palmini, Caroline Hewison, Fiona McFarlane, Elisabeta-Ana Savu, Robert N. Lightowlers, Zofia M. Chrzanowska-Lightowlers, Matthew Zorkau
Publikováno v:
Biology, Vol 10, Iss 10, p 1050 (2021)
Human mitochondria are highly dynamic organelles, fusing and budding to maintain reticular networks throughout many cell types. Although extending to the extremities of the cell, the majority of the network is concentrated around the nucleus in most
Externí odkaz:
https://doaj.org/article/a6c7c81087924629a84155d1cc1c4235
Autor:
Hyungju Park, Kyung-Seok Han, Jinsoo Seo, Jaekwang Lee, Shashank M. Dravid, Junsung Woo, Heejung Chun, Sukhee Cho, Jin Young Bae, Heeyoung An, Woohyun Koh, Bo-Eun Yoon, Rolando Berlinguer-Palmini, Guido Mannaioni, Stephen F. Traynelis, Yong Chul Bae, Se-Young Choi, C. Justin Lee
Publikováno v:
Molecular Brain, Vol 14, Iss 1, Pp 1-1 (2021)
Externí odkaz:
https://doaj.org/article/244da3947f774b08a6f188c2e50e5bf9
Autor:
Lucy M.V. Gee, Ben Barron-Millar, Jack Leslie, Claire Richardson, Marco Y.W. Zaki, Saimir Luli, Rachel A. Burgoyne, Rainie I.T. Cameron, Graham R. Smith, John G. Brain, Barbara Innes, Laura Jopson, Jessica K. Dyson, Katherine R.C. McKay, Alexandros Pechlivanis, Elaine Holmes, Rolando Berlinguer-Palmini, Stella Victorelli, George F. Mells, Richard N. Sandford, Jeremy Palmer, John A. Kirby, Christos Kiourtis, Joao Mokochinski, Zoe Hall, Thomas G. Bird, Lee A. Borthwick, Christopher M. Morris, Peter S. Hanson, Diana Jurk, Elizabeth A. Stoll, Fiona E.N. LeBeau, David E.J. Jones, Fiona Oakley
Publikováno v:
Gee, L M V, Barron-Millar, B, Leslie, J, Richardson, C, Zaki, M Y W, Luli, S, Burgoyne, R, Cameron, R I T, Smith, G R, Brain, J G, Innes, B, Jopson, L, Dyson, J K, McKay, K R C, Pechlivanis, A, Holmes, E, Berlinguer-Palmini, R, Victorelli, S, Mells, G F, Sandford, R N, Palmer, J, Kirby, J, Kiourtis, C, Mokochinski, J, Hall, Z, Bird, T G, Borthwick, L A, Morris, C, Hanson, P, Jurk, D, Stoll, E, LeBeau, F, Jones, D & Oakley, F 2022, ' Anti-Cholestatic therapy with Obeticholic Acid improves short term memory in bile duct ligated mice ', The American Journal of Pathology . https://doi.org/10.1016/j.ajpath.2022.09.005
Patients with cholestatic liver disease, including those with primary biliary cholangitis, can experience symptoms of impaired cognition or brain fog. This phenomenon remains unexplained and is currently untreatable. Bile duct ligation (BDL) is an es
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a70d70f37cc3ec34fd9fc440f82313fc
