Výsledky vyhledávání - "Rolande Berthier"

Cryptic O2–-generating NADPH oxidase in dendritic cells

Autor: Sylvie Elsen, Anne Papaioannou, Patrice N. Marche, Rolande Berthier, Pierre V. Vignais, Jacques Doussiere, Mathias Faure, Nathalie Grandvaux, Christian L. Villiers

Publikováno v: Journal of Cell Science. 117:2215-2226

All the components of the O(2)(-)-generating NADPH oxidase typically found in neutrophils, namely a membrane-bound low potential flavocytochrome b and oxidase activation factors of cytosolic origin, are immunodetectable in murine dendritic cells (DCs

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3df5a165f361124c93f15d257c81926
https://doi.org/10.1242/jcs.01085

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T Lymphocytes Potentiate Murine Dendritic Cells to Produce IL-12

Autor: Serge M. Candéias, Patrice N. Marche, Rolande Berthier, Véronique Collin, Alexandra Rizzitelli

Publikováno v: Journal of Immunology
Journal of Immunology, Publisher : Baltimore : Williams & Wilkins, c1950-. Latest Publisher : Bethesda, MD : American Association of Immunologists, 2002, 169 (8), pp.4237-45
Journal of Immunology, 2002, 169 (8), pp.4237-45

International audience; IL-12 is mainly produced by CD8alpha(+) dendritic cells (DCs) and induces Th1 polarization of the immune response. We investigated the influence of lymphocytes on splenic DC (SDC) and thymic DC (TDC) development and on their I

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::927b218ec5886b21d0d734f75de5e976
https://doi.org/10.4049/jimmunol.169.8.4237

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The cytoplasmic domain of Mpl receptor transduces exclusive signals in embryonic and fetal hematopoietic cells

Autor: Isabelle Dusanter-Fourt, Georges Uzan, Laurence Cocault, Michèle Souyri, C Challier, Nadine Binart, Rolande Berthier

Publikováno v: Blood. 100:2063-2070

The Mpl receptor plays an important role at the level of adult hematopoietic stem cells, but little is known of its function in embryonic and fetal hematopoiesis. We investigated the signals sent by the MPL cytoplasmic domain in fetal liver hematopoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9807959b3b29b8d8b76a3f0ab5ef8df5
https://doi.org/10.1182/blood.v100.6.2063

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Murine Dendritic Cells Derived from Myeloid Progenitors of the Thymus Are Unable to Produce Bioactive IL-12p70

Autor: Catherine Martinon-Ego, Rolande Berthier, Anne-Marie Laharie, Véronique Collin, François Cretin, Patrice N. Marche

Publikováno v: The Journal of Immunology. 166:5008-5017

Dendritic cells (DC) are present at low density in the thymus where they mediate negative selection of self-reactive thymocytes. Previous reports suggest that thymic DC (TDC) are a single population of lymphoid-related DC. In this study, we documente

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfbe32438555e5b0e4523322e18119e3
https://doi.org/10.4049/jimmunol.166.8.5008

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A two-step culture method starting with early growth factors permits enhanced production of functional dendritic cells from murine splenocytes

Autor: Anne Marie Laharie, Patrice N. Marche, Rolande Berthier, Catherine Martinon-Ego

Publikováno v: Journal of Immunological Methods. 239:95-107

Dendritic cells (DC) are professional antigen presenting cells (APC) able to activate naive T cells and initiate the immune response. They are present in most tissues at very low concentrations and are difficult to isolate. DC can be obtained in larg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fccaf69b603d0fb4323536fd45c772b
https://doi.org/10.1016/s0022-1759(00)00186-1

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Expression and function of receptors for extracellular matrix molecules in the differentiation of human megakaryocytesin vitro

Autor: Annie Schweitzer, Pascal Mossuz, Rolande Berthier, Annie Molla

Publikováno v: British Journal of Haematology. 98:819-827

The role of adhesive interactions with the extracellular matrix components of the bone marrow (BM) stroma has been widely studied in the differentiation of erythroid and myelomonocytic cells, but not in the megakaryocytic lineage. The development of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0359f1a7c3469549d93d99569f06abc2
https://doi.org/10.1046/j.1365-2141.1997.3013118.x

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Early events in erythroid differentiation: accumulation of the acidic peroxidoxin (PRP/TSA/NKEF-B)

Autor: Rolande Berthier, M Vinçon, G Goubin, Thierry Rabilloud, J J Lawrence, D Ferbus

Publikováno v: Biochemical Journal. 312:699-705

The acidic peroxidoxin [also named thiol-specific antioxidant protein (TSA) or protector protein (PRP)], which plays a role in the response against oxidative stress, is one of the major proteins of red blood cells. In this work, we show that this pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::055a2a178c4315fd7467ffb562974905
https://doi.org/10.1042/bj3120699

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Evidence for a selective inhibitory effect of thrombin on megakaryocyte progenitor growth mediated by the thrombin receptor

Autor: Jean-Luc Plantier, Rolande Berthier, Marie-Josèphe Rabiet, Annie Schweitzer, Yves Rival

Publikováno v: British Journal of Haematology. 87:755-762

Summary. An efficient method for the culture of human megakaryocyte precursors in serum-free medium has been developed facilitating study of the effect of regulators of megakaryocyte growth and maturation without interference by serum-derived factors

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddcdbfb26364fdc0b9748c6dc0189b0
https://doi.org/10.1111/j.1365-2141.1994.tb06735.x

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Serum‐free medium allows the optimal growth of human megakaryocyte progenitors compared with human plasma supplemented cultures: Role of TGF β

Autor: Odile Valiron, Annie Schweitzer, Gérard Marguerie, Rolande Berthier

Publikováno v: STEM CELLS. 11:120-129

The growth of human megakaryocyte progenitors from human bone marrow (BM) cells was compared using a methylcellulose semisolid assay supplemented either by normal human plasma or by a serum-free medium. Far better growth of megakaryocyte colonies fro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70d291bcf0915862ff76ca8c8d28787b
https://doi.org/10.1002/stem.5530110207

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Granulocyte-dendritic cell unbalance in the non-obese diabetic mice

Autor: Joëlle Morin, Christian Boitard, Amélie Chimènes, Rolande Berthier, Sarah Boudaly

Publikováno v: Cellular Immunology
Cellular Immunology, Elsevier, 2003, 223 (1), pp.13-25. ⟨10.1016/S0008-8749(03)00154-0⟩

Several investigators, including ourselves, have reported lower yield of GM-CSF bone marrow-derived dendritic cells (DC) with altered MHC class II and co-stimulatory molecules expression in the non-obese diabetic (NOD) mice. However, whether this def

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb623a81b128ee229a31781864bf5e22
https://hal.archives-ouvertes.fr/hal-02517340

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