Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Roland Zini"'
Autor:
Bijan Ghaleh, Mourad Chenoune, Renaud Tissier, Lys Darbera, Fanny Lidouren, Sandrine Pons, Roland Zini, Didier Morin, Alain Berdeaux
Publikováno v:
Resuscitation
Resuscitation, Elsevier, 2013, 84 (2), pp.249-55. ⟨10.1016/j.resuscitation.2012.06.030⟩
Resuscitation, Elsevier, 2013, 84 (2), pp.249-55. ⟨10.1016/j.resuscitation.2012.06.030⟩
Background Mitochondrial dysfunction is critical following ischemic disorders. Our goal was to determine whether mild hypothermia could limit this dysfunction through per-ischemic inhibition of reactive oxygen species (ROS) generation. Methods First,
Autor:
Renaud Tissier, N. Couvreur, M. Gervais, Roland Zini, Bijan Ghaleh, X. Waintraub, B. Enriquez, Alain Berdeaux, Chantal Mandet, Patrick Bruneval
Publikováno v:
Journal of Molecular and Cellular Cardiology. 42:79-87
Estrogens are known to activate the phosphatidyl-inosityl 3-kinase (PI3K)/Akt pathway, which is central in the cardioprotection afforded by ischemic postconditioning. Therefore, our goal was to investigate whether a phytoestrogen, genistein, could in
Autor:
Bijan Ghaleh, Xavier Monnet, Alain Berdeaux, Laurence Lucats, Roland Zini, Patrice Colin, Luc Hittinger
Publikováno v:
Cardiovascular Research. 70:391-398
Objectives Although the signalling pathways of late preconditioning have been extensively investigated, its consequence for myocardial metabolism remains unknown. Thus, myocardial oxygen consumption (MVO2) was evaluated before and under late precondi
Autor:
Nathalie Laurent, Sophie de Boüard, Jean-Sébastien Guillamo, Christo Christov, Roland Zini, Hélène Jouault, Patrice Andre, Vincent Lotteau, Marc Peschanski
Publikováno v:
Molecular Cancer Therapeutics. 3:129-136
Glioblastoma is a therapeutic challenge as a highly infiltrative, proliferative, and resistant tumor. Among novel therapeutic approaches, proteasome inhibition is very promising in controlling cell cycle and inducing apoptosis. This study investigate
Publikováno v:
Biochemical and Biophysical Research Communications
Biochemical and Biophysical Research Communications, Elsevier, 2003, 307 (3), pp.477-482. ⟨10.1016/S0006-291X(03)01203-8⟩
Biochemical and Biophysical Research Communications, Elsevier, 2003, 307 (3), pp.477-482. ⟨10.1016/S0006-291X(03)01203-8⟩
Rat brain mitochondria were successively submitted to anoxia and reoxygenation. The main mitochondrial functions were assessed at different reoxygenation times. Although the respiratory control ratio decreased, the activity for each one of the enzyme
Publikováno v:
Neuropharmacology
Neuropharmacology, Elsevier, 2003, 44 (5), pp.642-652. ⟨10.1016/S0028-3908(03)00041-8⟩
Neuropharmacology, Elsevier, 2003, 44 (5), pp.642-652. ⟨10.1016/S0028-3908(03)00041-8⟩
Epidemiological studies have reported that cigarette smoking may protect from neurodegenerative diseases such as Parkinson's disease. These protective effects are thought to be mediated by nicotine. Recent data showed that nicotine significantly decr
Publikováno v:
Life Sciences
Life Sciences, Elsevier, 2002, 71 (26), pp.3091-3108. ⟨10.1016/S0024-3205(02)02161-6⟩
Life Sciences, Elsevier, 2002, 71 (26), pp.3091-3108. ⟨10.1016/S0024-3205(02)02161-6⟩
Resveratrol protection on the main functions of purified rat brain mitochondria submitted to anoxia-reoxygenation was investigated. Resveratrol (
Publikováno v:
Pharmacological Research. 37:365-373
Inhibition of binding of the labelled antagonist (-)[3H]CGP 12177 by the full agonist (-)isoproterenol results in shallow competition curves, characteristic of the presence of both high- and low-affinity states of beta-adrenoceptors (betaAR). When in
Characterization of β-adrenergic receptors of freshly isolated astrocytes and neurons from rat brain
Publikováno v:
Life Sciences. 60:315-324
The binding and characteristics of rat brain beta-adrenergic receptors (beta-AR) isolated from astrocytes and neurons were investigated. Equilibrium binding experiments demonstrated that beta-AR were more concentrated on astrocytes than on neurons is
Autor:
Roland Zini, Markus Born, Françoise Brée, Bernard Testa, Jean-Paul Tillement, Kurt Hostettmann, Pierre-Alain Carrupt
Publikováno v:
Helvetica Chimica Acta, Vol. 79, No 4 (1996) pp. 1147-1158
A number of natural polyphenols (chlorogenic acid (9), cordigol (11), cordigone (12), danthrone (1), 1,5-dihydroxy-3-methoxyxanthone (2), eriosematin (7), flemichin D (8), frutinone A (6), mangiferin (4), quercetin (5), 1,3,6,7-tetrahydroxyxanthone (