Výsledky vyhledávání - "Roland Sänger"

A vaccine manufacturer’s approach to address medical needs related to seasonal and pandemic influenza viruses

Autor: Benoît Baras, Jeanne-Marie Devaster, Paul Gillard, Nancy Bouveret, Emmanuel Hanon, Roland Sänger, Louis Fries

Publikováno v: Influenza and Other Respiratory Viruses. 2:251-260

Vaccination is considered to be one of the most effective tools to decrease morbidity as well as mortality caused by influenza viruses. For the prevention of seasonal influenza, Fluarix and FluLaval have been marketed since 1987 and 1992, respectivel

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::cc61be4caad49fc7a6de1cc332b4e0e3
https://doi.org/10.1111/j.1750-2659.2008.00054.x

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Safety and reactogenicity profile of an adjuvanted H5N1 pandemic candidate vaccine in adults within a phase III safety trial

Autor: R S Fassakhov, Francisco Abad-Santos, Lars Rombo, Mamadou Dramé, Jan Hendrik Richardus, Romanenko Vv, José-María Bayas, José-Ramón de Juanes, H.C. Rumke, Tino F Schwarz, Frank von Sonnenburg, W. Ripley Ballou, Xavier Duval, Magda Campins, Covadonga Caso, Roland Sänger

Publikováno v: Vaccine. 26:2378-2388

A multicentre, randomized, phase III clinical trial in 5071 healthy adults was conducted to evaluate the safety and reactogenicity of a 15 microg HA dose of a candidate oil-in-water emulsion-based adjuvant system (AS)-adjuvanted split-virion H5N1 (AS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::140b14c2afb3efe56720a21f70162929
https://doi.org/10.1016/j.vaccine.2008.02.068

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Booster immunization with a hexavalent diphtheria, tetanus, acellular pertussis, hepatitis B, inactivated poliovirus vaccine and Haemophilus influenzae type b conjugate combination vaccine in the second year of life: Safety, immunogenicity and persistence of antibody responses

Autor: Lode Schuerman, Jeanne-Marie Jacquet, Ulrich Heininger, Roland Sänger

Publikováno v: Vaccine. 25:1055-1063

The immunogenicity and reactogenicity of booster vaccination with GSK Biologicals' hexavalent DTPa-HBV-IPV/Hib vaccine was assessed in toddlers aged 12-18 months previously primed with the same combination (N=341), or with DTPa-IPV/Hib and HBV admini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0b015f489cbc7dc5481edd0e2ac0bd9
https://doi.org/10.1016/j.vaccine.2006.09.060

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Assessment of nine candidate DTP-vaccines with reduced amount of antigen and/or without adjuvant as a fourth (booster-) dose in the second year of life

Autor: Anne Schuind, Heinz-Josef Schmitt, Jörg Faber, P. Habermehl, Hugues Bogaerts, J.B. du Prel, Hans L. Bock, Markus Knuf, Roland Sänger, Ralf Clemens

Publikováno v: Vaccine. 24:5627-5636

Background The incidence of local reactions to diphtheria-, tetanus and acellular pertussis (DTaP-) vaccines in infants and toddlers increases with each subsequent dose, and entire thigh swellings (ETS) have been reported. Lowering the amount of anti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776e2b1da7d24d59851b08aa3a7806a4
https://doi.org/10.1016/j.vaccine.2006.04.019

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Immunogenicity and Reactogenicity of Four Doses of Diphtheria-Tetanus-Three-Component Acellular Pertussis-Hepatitis B-Inactivated Polio Virus-Haemophilus influenzae Type b Vaccine Coadministered with 7-Valent Pneumococcal Conjugate Vaccine

Autor: Gudrun Maechler, Irmingard Tichmann-Schumann, Hans Mahler, Roland Sänger, Lode Schuerman, Johann Disselhoff, Ulrich Behre, Jeanne-Marie Jacquet, Peter Soemantri

Publikováno v: Pediatric Infectious Disease Journal. 24:70-77

Background The 7-valent pneumococcal (7vPn) conjugate vaccine is licensed for primary and booster vaccination according to the same immunization schedules as routinely recommended diphtheria-tetanus-pertussis-based childhood vaccines and can be coadm

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7795f2f14706517ef6f01179e1aaa5c
https://doi.org/10.1097/01.inf.0000148923.46453.48

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Pandemic preparedness: lessons learnt from H2N2 and H9N2 candidate vaccines

Autor: Roland Sänger, E. Neumeier, N. Hehme, W. Künzel, H. Engelmann

Publikováno v: Medical Microbiology and Immunology. 191:203-208

Vaccination against influenza is considered to be one of the key interventions in case of a pandemic. Unfortunately, shortages in vaccine supplies will occur because of the substantial increase in vaccine demands worldwide and the limited available s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f1f8f5c30e3f63b891f917234d70a98
https://doi.org/10.1007/s00430-002-0147-9

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C4A deficiency and nonresponse to hepatitis B vaccination

Autor: Christian Rittner, Roland Sänger, Roland Starke, Thomas Höhler, Anja Victor, Beate Stradmann-Bellinghausen, Peter M. Schneider

Publikováno v: Journal of Hepatology. 37:387-392

Hepatitis B vaccination failure has been linked to the presence of certain human leukocyte antigen class II alleles. However, the functional background of these associations has remained unclear. Complement component C 4 is encoded within the major h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fefb7a2407b589d0ecee9046aee046c
https://doi.org/10.1016/s0168-8278(02)00205-2

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A new accelerated vaccination schedule for rapid protection against hepatitis A and B

Autor: Hans Dieter Nothdurft, Jens Vollmar, Peter Kern, Jane N. Zuckerman, J Knobloch, M Dietrich, Roland Sänger

Publikováno v: Vaccine. 20:1157-1162

Background: Increasing travel stresses the requirement for rapid protection against infections such as hepatitis A and B.Methods: This randomised, multicentre study investigated an accelerated vaccination schedule using a combined hepatitis A and B v

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https://doi.org/10.1016/s0264-410x(01)00432-7

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Ten Years of Experience with the Trivalent Split-Influenza Vaccine, Fluarix???

Autor: W. Künzel, Roland Sänger, Carmen Raderecht, Christian Van Hoecke, Norbert W. Hehme, Frank Petschke, Gisela Türk

Publikováno v: Clinical Drug Investigation. 22:751-769

The trivalent inactivated split-influenza vaccine, Fluarix™, has been available since 1992. To assess the safety and immunogenicity of the vaccine from studies in healthy adults and the elderly performed from 1992 to 2001 to comply with European Un

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c99234a2a94ec371a99e1f1875b01e74
https://doi.org/10.2165/00044011-200222110-00004

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