Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Roland Renetseder"'
Publikováno v:
Journal of Molecular Biology, 168(1), 163-179. Academic Press
The previously published three-dimensional structure of porcine pancreatic prophospholipase A 2 at 3resolution was found to be incompatible with the structures of bovine phospholipase A 2 and bovine prophospholipase A 2 . This was unexpected because
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9f1e10567a812396915b50c074b6a5a
https://doi.org/10.1016/s0022-2836(83)80328-3
https://doi.org/10.1016/s0022-2836(83)80328-3
Publikováno v:
Acta Crystallographica Section B Structural Science. 42:602-605
Data collection has always been a time-consuming operation in protein X-ray crystallography. This situation drastically changed with the introduction of two-dimensional area detectors. In this article the first successful refinement of a protein stru
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6085221ea5722158798ad4f043bd4382
https://doi.org/10.1107/s0108768186097677
https://doi.org/10.1107/s0108768186097677
Publikováno v:
Journal of Biological Chemistry. 260:11627-11634
The refined high resolution crystal structure of the bovine phospholipase A2 was compared with its counterpart from the venom of Crotalus atrox, the western diamondbacked rattlesnake. The strong similarity in their backbone conformations forms the ba
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4f3f83336b64b7e251e472abb419b742
https://doi.org/10.1016/s0021-9258(17)39077-4
https://doi.org/10.1016/s0021-9258(17)39077-4
Publikováno v:
Journal of Molecular Biology, 200(1). Academic Press
Bovine pancreatic phospholipase A2 covalently inhibited by p-bromo-phenacyl-bromide was crystallized from 50% (v/v) 2-methyl-2,4-pentanediol. The space group was P3(1)21 with cell dimensions a = b = 46.73 A and c = 102.5 A (1 A = 0.1 nm). Diffraction
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b764007b67d6766b14bd0c695bca2ac
https://research.rug.nl/en/publications/d8da6158-94ca-4ad1-a2f0-d8653f68b66c
https://research.rug.nl/en/publications/d8da6158-94ca-4ad1-a2f0-d8653f68b66c
Publikováno v:
IUPHAR 9th International Congress of Pharmacology ISBN: 9780333371350
Inhibition of enzymes is usually brought about by reagents which attack essential functional groups in the active site or by blocking the entrance to the active site. If one for example reacts the essential His 48 in phospholipase A2 with an acylatin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::77435063c54b2de7b3be9c30292ec765
https://doi.org/10.1007/978-1-349-86029-6_5
https://doi.org/10.1007/978-1-349-86029-6_5