Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Roland Rabl"'
Autor:
Shirin Sharghi, Stefanie Flunkert, Magdalena Daurer, Roland Rabl, Boris Philippe Chagnaud, Marcello Leopoldo, Enza Lacivita, Birgit Hutter-Paier, Manuela Prokesch
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionAutism spectrum disorder (ASD) is a persistent neurodevelopmental condition characterized by two core behavioral symptoms: impaired social communication and interaction, as well as stereotypic, repetitive behavior. No distinct cause of AS
Externí odkaz:
https://doaj.org/article/bf00381a84fc4ffaa83f71f23204e7fe
Autor:
Agnes Molnar-Kasza, Barbara Hinteregger, Joerg Neddens, Roland Rabl, Stefanie Flunkert, Birgit Hutter-Paier
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Amyotrophic lateral sclerosis (ALS) still depicts an incurable and devastating disease. Drug development efforts are mostly based on superoxide dismutase 1 gene (SOD1)-G93A mice that present a very strong and early phenotype, allowing only a short ti
Externí odkaz:
https://doaj.org/article/6cfbeb8bdd8e4c9fa1a428a29d137ea9
Autor:
Gernot F. Grabner, Nermeen Fawzy, Maria A. Pribasnig, Markus Trieb, Ulrike Taschler, Michael Holzer, Martina Schweiger, Heimo Wolinski, Dagmar Kolb, Angela Horvath, Rolf Breinbauer, Thomas Rülicke, Roland Rabl, Achim Lass, Vanessa Stadlbauer, Birgit Hutter-Paier, Rudolf E. Stauber, Peter Fickert, Rudolf Zechner, Gunther Marsche, Thomas O. Eichmann, Robert Zimmermann
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 5, Pp 1020-1031 (2019)
Bis(monoacylglycerol)phosphate (BMP) is a phospholipid that is crucial for lipid degradation and sorting in acidic organelles. Genetic and drug-induced lysosomal storage disorders (LSDs) are associated with increased BMP concentrations in tissues and
Externí odkaz:
https://doaj.org/article/6811fbb03319497cbbdc699b457cff47
Autor:
Estibaliz Santiago-Mujica, Stefanie Flunkert, Roland Rabl, Joerg Neddens, Tina Loeffler, Birgit Hutter-Paier
Publikováno v:
Heliyon, Vol 5, Iss 3, Pp e01293- (2019)
Niemann-Pick type C disease (NPC) is a fatal autosomal recessive disorder characterized by a defect in the intracellular transport of lipoproteins leading to the accumulation of lipids in diverse tissues. A visceral and neuronal phenotype mimicking h
Externí odkaz:
https://doaj.org/article/fb3ad7c087c74498bf11829d5c6ef972
Autor:
Barbara Scherz, Roland Rabl, Stefanie Flunkert, Siegfried Rohler, Joerg Neddens, Nicole Taub, Magdalena Temmel, Ute Panzenboeck, Vera Niederkofler, Robert Zimmermann, Birgit Hutter-Paier
Publikováno v:
PLoS ONE, Vol 13, Iss 5, p e0197674 (2018)
Transgenic mouse models are indispensable tools to mimic human diseases and analyze the effectiveness of related new drugs. For a long time amyotrophic lateral sclerosis (ALS) research depended on only a few mouse models that exhibit a very strong an
Externí odkaz:
https://doaj.org/article/47f096b395ef46148adcfa7f08e8eb0d
Autor:
Janine Kutzsche, Sarah Schemmert, Markus Tusche, Jörg Neddens, Roland Rabl, Dagmar Jürgens, Oleksandr Brener, Antje Willuweit, Birgit Hutter-Paier, Dieter Willbold
Publikováno v:
Molecules, Vol 22, Iss 10, p 1693 (2017)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that is associated with the aggregation of the amyloid β protein (Aβ). Aβ oligomers are currently thought to be the major neurotoxic agent responsible for disease development a
Externí odkaz:
https://doaj.org/article/be862b0b46e04a7ab5f28f2feca41958
Autor:
Joshua Adekunle Babalola, Tina Loeffler, Irene Schilcher, Livia Breznik, Roland Rabl, Spyridon Sideromenos, Stefanie Flunkert, Manuela Prokesch, Gerald Hoefler, Birgit Hutter‐Paier
Publikováno v:
Alzheimer's & Dementia. 18
Autor:
Livia Breznik, Spyridon Sideromenos, Agnes Molnar-Kasza, Roland Rabl, Stefanie Flunkert, Manuela Prokesch, Birgit Hutter-Paier
Publikováno v:
Molecular Genetics and Metabolism. 135:S25-S26
Autor:
Roland Rabl, Joerg Neddens, Barbara Hinteregger, Agnes Molnar-Kasza, Stefanie Flunkert, Birgit Hutter-Paier
Publikováno v:
Frontiers in Molecular Neuroscience
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Amyotrophic lateral sclerosis (ALS) still depicts an incurable and devastating disease. Drug development efforts are mostly based on superoxide dismutase 1 gene (SOD1)-G93A mice that present a very strong and early phenotype, allowing only a short ti
Autor:
Estibaliz Santiago-Mugica, Stefanie Flunkert, Iera Hernandez, Birgit Hutter-Paier, Stephan Kurat, Roland Rabl
Publikováno v:
Alzheimer's & Dementia. 14