Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Roland R. Rueckert"'
Autor:
Roland R Rueckert, V. Holoubek
Publikováno v:
Biochemical and biophysical research communications. 15(2)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5cbcc8d51fc39e6f4b2b0257aef7c44
https://pubmed.ncbi.nlm.nih.gov/26410911
https://pubmed.ncbi.nlm.nih.gov/26410911
Autor:
Michael G. Rossmann, Edward Arnold, John W. Erickson, Elizabeth A. Frankenberger, James P. Griffith, Hans-Jürgen Hecht, John E. Johnson, Greg Kamer, Ming Luo, Anne G. Mosser, Roland R. Rueckert, Barbara Sherry, Gerrit Vriend
Publikováno v:
Selected Papers of Michael G Rossmann with Commentaries ISBN: 9789814513340
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ed46cc8da3c12a64631d02886f20dde
https://doi.org/10.1142/9789814513357_0021
https://doi.org/10.1142/9789814513357_0021
Publikováno v:
Journal of Virology. 72:1210-1218
Three drug-dependent mutants of human rhinovirus 16 (HRV16) were characterized by sequence analyses of spontaneous mutant isolates and were genetically reconstructed from a parental cDNA plasmid. These mutants formed plaques in the presence but not i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::497a25a4a6e92d99cb63cca297a2d72e
https://doi.org/10.1128/jvi.72.2.1210-1218.1998
https://doi.org/10.1128/jvi.72.2.1210-1218.1998
Publikováno v:
Acta Crystallographica Section D Biological Crystallography. 51:490-495
Capsid-binding drugs that inhibit the first stage of picornaviral uncoating were used to select drug-resistant mutants of the Sabin strain of poliovirus type 3. Such mutants provide information about parts of the capsid that are important for functio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::945ddfb0c2f2ff4c7dc0a61e4e87673e
https://doi.org/10.1107/s0907444994013491
https://doi.org/10.1107/s0907444994013491
Publikováno v:
Journal of Virology. 68:8193-8201
We have previously described the use of an uncoating inhibitor, WIN 51711, to select drug-resistant mutants of the Sabin strain of poliovirus type 3. Two-thirds of the mutants proved to be dependent on the drug for plaque formation because of extreme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::739a415487754426339c75e451a80483
https://doi.org/10.1128/jvi.68.12.8193-8201.1994
https://doi.org/10.1128/jvi.68.12.8193-8201.1994
Autor:
William J. Ray, Anette Schneemann, Ranjit Dasgupta, Vijay S. Reddy, Roland R. Rueckert, Adam Zlotnick, John E. Johnson
Publikováno v:
Journal of Biological Chemistry. 269:13680-13684
Maturation of noninfectious nodavirus provirions occurs by autoproteolytic cleavage of most of the 180 copies of the alpha-protein that make up the icosahedral capsid. This maturation, which is much slower than viral assembly, produces an infectious
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::522de92d56717f329f126e5ddc14a9e5
https://doi.org/10.1016/s0021-9258(17)36883-7
https://doi.org/10.1016/s0021-9258(17)36883-7
Autor:
Marcos A. Oliveira, Michael G. Rossmann, Mark A. McKinlay, Daniel C. Pevear, Guy D. Diana, Iwona Minor, Roland R. Rueckert, Wai-Ming Lee, Marcia J. Kremer, Frank J. Dutko, Rui Zhao
Publikováno v:
Structure. 1:51-68
Background : Rhinoviruses and the homologous polioviruses have hydrophobic pockets below their receptor-binding sites, which often contain unidentified electron density (‘pocket factors'). Certain antiviral compounds also bind in the pocket, displa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bda697cd30c5510f7353de29bb070bf4
https://doi.org/10.1016/0969-2126(93)90008-5
https://doi.org/10.1016/0969-2126(93)90008-5
Publikováno v:
Journal of Virology. 67:2110-2122
Maturation of picornaviruses involves assembly of a "provirion," which undergoes an autocatalytic cleavage of VP0 to VP2 plus VP4. RNA transcripts from a cDNA clone of human rhinovirus 14 mutated at asparagine 68, one of the residues in the maturatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::881d6a8dc7868be4ca0c4ee886ccf9e7
https://doi.org/10.1128/jvi.67.4.2110-2122.1993
https://doi.org/10.1128/jvi.67.4.2110-2122.1993
Publikováno v:
Journal of Virology. 67:2245-2254
WIN compounds inhibit attachment of human rhinovirus 14 by binding to a hydrophobic pocket within the capsid and inducing conformational changes in the canyon floor, the region that binds the cellular receptor. To study the basis of drug resistance,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d94a73070283c2abba9478fdd5c3839
https://doi.org/10.1128/jvi.67.4.2245-2254.1993
https://doi.org/10.1128/jvi.67.4.2245-2254.1993
Publikováno v:
Proceedings of the National Academy of Sciences. 89:11146-11150
Flock house virus is an insect virus belonging to the family Nodaviridae; members of this family are characterized by a small bipartite positive-stranded RNA genome. The larger genomic segment, RNA1, encodes viral replication proteins, whereas the sm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e996947ef482771563cb9d07132f78c
https://doi.org/10.1073/pnas.89.23.11146
https://doi.org/10.1073/pnas.89.23.11146