Zobrazeno 1 - 10
of 145
pro vyhledávání: '"Roland R, Regoes"'
Autor:
Bernardo Antunes, Caroline Zanchi, Paul R Johnston, Bar Maron, Christopher Witzany, Roland R Regoes, Zvi Hayouka, Jens Rolff
Publikováno v:
PLoS Biology, Vol 22, Iss 7, p e3002692 (2024)
The prevalence of antibiotic-resistant pathogens has become a major threat to public health, requiring swift initiatives for discovering new strategies to control bacterial infections. Hence, antibiotic stewardship and rapid diagnostics, but also the
Externí odkaz:
https://doaj.org/article/ad2c8ebf23dd443cb17b6e234349bd7e
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
The relationship between virulence and pathogen clearance is not well understood. Here, using bacterial infections in Drosophila melanogaster as a model system, the authors demonstrate an approach to disentangle the drivers of virulence and assess th
Externí odkaz:
https://doaj.org/article/e92b90880db9492a8e422f952d7a4ca2
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The recalcitrance of biofilms to antimicrobials is a multi-factorial phenomenon, including genetic, physical, and physiological changes. Individually, they often cannot account for biofilm recalcitrance. However, their combination can increase the mi
Externí odkaz:
https://doaj.org/article/ec5e51282a1e484082d2401fb41a08df
Publikováno v:
PLoS Computational Biology, Vol 18, Iss 7, p e1010329 (2022)
Bacteria have adaptive immunity against viruses (phages) in the form of CRISPR-Cas immune systems. Currently, 6 types of CRISPR-Cas systems are known and the molecular study of three of these has revealed important molecular differences. It is unknow
Externí odkaz:
https://doaj.org/article/c633973789b34cd39e1a34a419fd2358
Autor:
Judith A. Bouman, Sarah Kadelka, Silvia Stringhini, Francesco Pennacchio, Benjamin Meyer, Sabine Yerly, Laurent Kaiser, Idris Guessous, Andrew S. Azman, Sebastian Bonhoeffer, Roland R. Regoes
Publikováno v:
Epidemics, Vol 39, Iss , Pp 100572- (2022)
Serosurveys are an important tool to estimate the true extent of the current SARS-CoV-2 pandemic. So far, most serosurvey data have been analyzed with cutoff-based methods, which dichotomize individual measurements into sero-positives or negatives ba
Externí odkaz:
https://doaj.org/article/af6999fbf9024b53b8183c3bfaadde19
Publikováno v:
PLoS Pathogens, Vol 17, Iss 3, p e1009443 (2021)
Antimicrobial peptides (AMPs) are key components of innate immune defenses. Because of the antibiotic crisis, AMPs have also come into focus as new drugs. Here, we explore whether prior exposure to sub-lethal doses of AMPs increases bacterial surviva
Externí odkaz:
https://doaj.org/article/8dcca1faaa0746a9b81429b94b039cc5
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 2, p e1008728 (2021)
Large-scale serological testing in the population is essential to determine the true extent of the current SARS-CoV-2 pandemic. Serological tests measure antibody responses against pathogens and use predefined cutoff levels that dichotomize the quant
Externí odkaz:
https://doaj.org/article/f1f00d5d3c5545e4a1806ed40d25f4fa
Publikováno v:
PLoS Biology, Vol 18, Iss 12, p e3001010 (2020)
An often-returning question for not only HIV-1, but also other organisms, is how predictable evolutionary paths are. The environment, mutational history, and random processes can all impact the exact evolutionary paths, but to which extent these fact
Externí odkaz:
https://doaj.org/article/d83ee067ecc64c489e7516994a3109ae
Autor:
Peter Ashcroft, Jana S. Huisman, Sonja Lehtinen, Judith A. Bouman, Christian L. Althaus, Roland R. Regoes, Sebastian Bonhoeffer
Publikováno v:
Swiss Medical Weekly, Vol 150, Iss 3132 (2020)
Externí odkaz:
https://doaj.org/article/7c1a456fad82474299134412a4ccc197
Publikováno v:
Trends in Microbiology. 30:841-852
Biofilms are communities of bacteria forming high-density sessile colonies. Such a lifestyle comes associated with costs and benefits: while the growth rate of biofilms is often lower than that of their free-living counterparts, this cost is readily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0139cc3ffe6506f2a1f5d86469b5bc42
https://doi.org/10.1016/j.tim.2022.02.005
https://doi.org/10.1016/j.tim.2022.02.005