Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Roland N. Wagner"'
Autor:
Thomas Kocher, Roland N. Wagner, Alfred Klausegger, Christina Guttmann-Gruber, Stefan Hainzl, Johann W. Bauer, Julia Reichelt, Ulrich Koller
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 18, Iss , Pp 496-507 (2019)
Current gene-editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin disease, suffer from low efficiencies and safety concerns that complicate implementation in clinical sett
Externí odkaz:
https://doaj.org/article/bec181537d374084adb000f27699b760
Autor:
Laura De Rosa, Roland N. Wagner, Barbara Kofler, Verena Wally, Josefina Piñón Hofbauer, Johann W. Bauer, Matthias Schmuth, Michele De Luca
Publikováno v:
Experimental Dermatology
Continuous exposure of the skin to environmental, mechanical and chemical stress necessitates constant self‐renewal of the epidermis to maintain its barrier function. This self‐renewal ability is attributed to epidermal stem cells (EPSCs), which
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72a9688c9d3aa33c5f8ee01531189129
https://doi.org/10.1111/exd.14305
https://doi.org/10.1111/exd.14305
Autor:
Roland N. Wagner, Michael Wießner, Andreas Friedrich, Johanna Zandanell, Hannelore Breitenbach-Koller, Johann W. Bauer
Publikováno v:
International Journal of Molecular Sciences. 24:6101
Nonsense mutations trigger premature translation termination and often give rise to prevalent and rare genetic diseases. Consequently, the pharmacological suppression of an unscheduled stop codon represents an attractive treatment option and is of hi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b64bc04b92dd8a5b2bbaec0999902693
https://doi.org/10.3390/ijms24076101
https://doi.org/10.3390/ijms24076101
Autor:
Johann W. Bauer, Thomas Kocher, Alfred Klausegger, Julia Reichelt, Roland N. Wagner, Stefan Hainzl, Christina Guttmann-Gruber, Ulrich Koller
Publikováno v:
Molecular Therapy. Nucleic Acids
Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 496-507 (2019)
Molecular Therapy: Nucleic Acids, Vol 18, Iss, Pp 496-507 (2019)
Current gene-editing approaches for treatment of recessive dystrophic epidermolysis bullosa (RDEB), an inherited, severe form of blistering skin disease, suffer from low efficiencies and safety concerns that complicate implementation in clinical sett
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb5b8cdd45cb9e79fa286106e69c561
http://europepmc.org/articles/PMC6838546
http://europepmc.org/articles/PMC6838546
Autor:
Andrea D'Osualdo, Christian X Weichenberger, Roland N Wagner, Adam Godzik, John Wooley, John C Reed
Publikováno v:
PLoS ONE, Vol 6, Iss 11, p e27396 (2011)
The "Function to Find Domain" (FIIND)-containing proteins CARD8 (Cardinal; Tucan) and NLRP1 (NALP1; NAC) are well known components of inflammasomes, multiprotein complexes responsible for activation of caspase-1, a regulator of inflammation and innat
Externí odkaz:
https://doaj.org/article/58570e84f44541c89c521a4dd5f68504
Publikováno v:
Retrovirology
Background HIV-1 protease (PR) is essential for viral infectivity as it cleaves Gag and Gag-Pol polyprotein precursors during viral maturation. Recent evidence suggests that cellular proteins can also be cleaved by PR, perhaps representing an importa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17fca5f5c76b08fb2e1ea517e368efc9
https://doi.org/10.1186/s12977-015-0200-6
https://doi.org/10.1186/s12977-015-0200-6
Publikováno v:
Innate immunity. 18(1)
Nucleotide-binding oligomerization domain-containing protein (NOD)1 and NOD2 are intracellular pattern recognition receptors (PRRs) of the nucleotide-binding domain and leucine-rich repeat containing (NLR) gene family involved in innate immune respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::734f408ff4387cc5e844548e4bc41ae1
https://pubmed.ncbi.nlm.nih.gov/21310790
https://pubmed.ncbi.nlm.nih.gov/21310790
Autor:
Adam Godzik, Andrea D'Osualdo, John C. Reed, John Wooley, Christian X. Weichenberger, Roland N. Wagner
Publikováno v:
PloS one, vol 6, iss 11
PLoS ONE, Vol 6, Iss 11, p e27396 (2011)
PLoS ONE
PLoS ONE, Vol 6, Iss 11, p e27396 (2011)
PLoS ONE
The "Function to Find Domain" (FIIND)-containing proteins CARD8 (Cardinal; Tucan) and NLRP1 (NALP1; NAC) are well known components of inflammasomes, multiprotein complexes responsible for activation of caspase-1, a regulator of inflammation and innat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6daabb3eca9f6dd479d5fd004edecb82
https://escholarship.org/uc/item/7pc4z99c
https://escholarship.org/uc/item/7pc4z99c
Autor:
Alfred Klausegger, E. Nischler, Helmut Hintner, Roland N. Wagner, F. Pletschacher, Johann W. Bauer
Publikováno v:
Archives of dermatological research. 303(5)
Darier's disease (DD, OMIM 124200) is an autosomal dominant inherited genodermatosis characterized by warty papules and plaques in seborrheic areas, and loss of adhesion between suprabasal epidermal keratinocytes (acantholysis) and abnormal keratinis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2c62c00b085bfdc5508bc8c3ef787be
https://pubmed.ncbi.nlm.nih.gov/21519848
https://pubmed.ncbi.nlm.nih.gov/21519848
Publikováno v:
PLoS ONE
PLoS ONE, Vol 4, Iss 4, p e4931 (2009)
PLoS ONE, Vol 4, Iss 4, p e4931 (2009)
Members of the Nod-like receptor (NLR) family recognize intracellular pathogens and recruit a variety of effector molecules, including pro-caspases and kinases, which in turn are implicated in cytokine processing and NF-κB activation. In order to el
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c41b5e78f70915e3250cc77d77a257b5
https://pubmed.ncbi.nlm.nih.gov/19337385
https://pubmed.ncbi.nlm.nih.gov/19337385