Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Roland L Knorr"'
Autor:
Katharina Sporbeck, Maximilian L. Haas, Carmen J. Pastor-Maldonado, David S. Schüssele, Catherine Hunter, Zsuzsanna Takacs, Ana L. Diogo de Oliveira, Mirita Franz-Wachtel, Chara Charsou, Simon G. Pfisterer, Andrea Gubas, Patricia K. Haller, Roland L. Knorr, Manuel Kaulich, Boris Macek, Eeva-Liisa Eskelinen, Anne Simonsen, Tassula Proikas-Cezanne
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-23 (2023)
Abstract Human WIPI β-propellers function as PI3P effectors in autophagy, with WIPI4 and WIPI3 being able to link autophagy control by AMPK and TORC1 to the formation of autophagosomes. WIPI1, instead, assists WIPI2 in efficiently recruiting the ATG
Externí odkaz:
https://doaj.org/article/d0288956339a424480d31074800a3152
Autor:
Jan Steinkühler, Roland L. Knorr, Ziliang Zhao, Tripta Bhatia, Solveig M. Bartelt, Seraphine Wegner, Rumiana Dimova, Reinhard Lipowsky
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Membrane fission of a cell into two daughters is a core ability of cell-based life. Here the authors show that in artificial cells division can be controlled by regulating membrane curvature using low protein density.
Externí odkaz:
https://doaj.org/article/4547f2156e224af59c23cf11eea3cc57
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101466- (2020)
Summary: Autophagy is an intracellular degradation process that is mediated by de novo formation of autophagosomes. Autophagosome formation involves dynamic morphological changes; a disk-shaped membrane cisterna grows, bends to become a cup-shaped st
Externí odkaz:
https://doaj.org/article/fd63adf01fb54f95b21259dca5e0e033
Autor:
Yunuen Avalos-Padilla, Roland L. Knorr, Rosario Javier-Reyna, Guillermina García-Rivera, Reinhard Lipowsky, Rumiana Dimova, Esther Orozco
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 8 (2018)
The endosomal sorting complex required for transport (ESCRT) orchestrates cell membrane-remodeling mechanisms in eukaryotes, including endocytosis. However, ESCRT functions in phagocytosis (ingestion of ≥250 nm particles), has been poorly studied.
Externí odkaz:
https://doaj.org/article/722f756516944f0594c2fb68797d5e9f
Autor:
Daisuke Noshiro, Nobuo N. Noda, Yuko Fujioka, Jahangir Md. Alam, Roland L. Knorr, Kuninori Suzuki, Alexander I. May, Yasushi Okada, Yoshinori Ohsumi, Kazunari Mouri, Toshio Ando
Publikováno v:
Nature. 578:301-305
Many biomolecules undergo liquid–liquid phase separation to form liquid-like condensates that mediate diverse cellular functions1,2. Autophagy is able to degrade such condensates using autophagosomes—double-membrane structures that are synthesize
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eacdf4f56ed8ac7c79eeab2d870f0f25
https://doi.org/10.1038/s41586-020-1977-6
https://doi.org/10.1038/s41586-020-1977-6
Autor:
Sebastian W. Schultz, Roland L. Knorr, Simona M. Migliano, Andreas Brech, Jaime Agudo-Canalejo, Alexander I. May, Haruka Chino, Harald Stenmark, Noboru Mizushima, Ikuko Koyama-Honda, Chieko Saito
Publikováno v:
Autophagy. 17:1046-1048
Phase-separated droplets with liquid-like properties can be degraded by macroautophagy/autophagy, but the mechanism underlying this degradation is poorly understood. We have recently derived a physical model to investigate the interaction between aut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1dc4b2d04a71d7e5704dcdf33c7ecd20
https://doi.org/10.1080/15548627.2021.1887548
https://doi.org/10.1080/15548627.2021.1887548
Autor:
Roland L Knorr, Hitoshi Nakatogawa, Yoshinori Ohsumi, Reinhard Lipowsky, Tobias Baumgart, Rumiana Dimova
Publikováno v:
PLoS ONE, Vol 9, Iss 12, p e115357 (2014)
Autophagy is a cellular degradation pathway involving the shape transformation of lipid bilayers. During the onset of autophagy, the water-soluble protein Atg8 binds covalently to phosphatdylethanolamines (PEs) in the membrane in an ubiquitin-like re
Externí odkaz:
https://doaj.org/article/56023a747b34454c927bfe3fae808c8b
Publikováno v:
Journal of cell biology, 2021, Vol.220(10), pp.e202103175 [Peer Reviewed Journal]
Protein-rich droplets, such as stress granules, P-bodies, and the nucleolus, perform diverse and specialized cellular functions. Recent evidence has shown the droplets, which are also known as biomolecular condensates or membrane-less compartments, f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8daa5347da051447d8d15be9fe6d602
https://pubmed.ncbi.nlm.nih.gov/34427635
https://pubmed.ncbi.nlm.nih.gov/34427635
Autor:
Ziliang Zhao, Solveig Mareike Bartelt, Rumiana Dimova, Reinhard Lipowsky, Jan Steinkühler, Roland L. Knorr, Tripta Bhatia, Seraphine V. Wegner
Publikováno v:
Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
The proliferation of life on earth is based on the ability of single cells to divide into two daughter cells. During cell division, the plasma membrane undergoes a series of morphological transformations which ultimately lead to membrane fission. Her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c4271d8eb36ac5fd580231cbbfb6591
https://hdl.handle.net/21.11116/0000-0005-B1C9-021.11116/0000-0005-B1CB-E
https://hdl.handle.net/21.11116/0000-0005-B1C9-021.11116/0000-0005-B1CB-E
Publikováno v:
iScience, Vol 23, Iss 9, Pp 101466-(2020)
iScience
iScience
Summary Autophagy is an intracellular degradation process that is mediated by de novo formation of autophagosomes. Autophagosome formation involves dynamic morphological changes; a disk-shaped membrane cisterna grows, bends to become a cup-shaped str
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e28bf73ee0df6fed286882b8fd4dcca